Detailed information NTG0133441

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DE10444_RS07230
• Genome accession: NZ_CP012392
• Coordinates: 1398639..1400930 (+)
• Length: 763 a.a.
• NCBI ID: WP_002223891.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain DE10444
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1393639..1405930

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DE10444_RS07200 (DE10444_1339)	-	1394832..1395548 (-)	717	WP_065824978.1	hypothetical protein	-
DE10444_RS07205 (DE10444_1340)	yjgA	1395595..1396107 (-)	513	WP_002226469.1	ribosome biogenesis factor YjgA	-
DE10444_RS07210 (DE10444_1341)	pmbA	1396261..1397592 (+)	1332	WP_002229293.1	metalloprotease PmbA	-
DE10444_RS07215	-	1397604..1397795 (+)	192	WP_019273772.1	hypothetical protein	-
DE10444_RS07220 (DE10444_1342)	-	1397889..1398092 (-)	204	WP_002217533.1	cold-shock protein	-
DE10444_RS07225 (DE10444_1343)	clpS	1398335..1398637 (+)	303	WP_002221161.1	ATP-dependent Clp protease adapter ClpS	-
DE10444_RS07230 (DE10444_1344)	clpC	1398639..1400930 (+)	2292	WP_002223891.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
DE10444_RS07235 (DE10444_1345)	-	1400970..1404068 (-)	3099	WP_002229287.1	type I restriction endonuclease subunit R	-
DE10444_RS07240 (DE10444_1346)	-	1404147..1404515 (-)	369	WP_002259877.1	restriction endonuclease subunit S	-
DE10444_RS07245 (DE10444_1347)	-	1404540..1405217 (+)	678	WP_002215827.1	IS1595-like element ISNme3 family transposase	-

Sequence

Protein

• Length: 763 a.a.
• Molecular weight: 84245.10 Da
• Isoelectric Point: 6.8224

>NTDB_id=133441 DE10444_RS07230 WP_002223891.1 1398639..1400930(+) (clpC) [Neisseria meningitidis strain DE10444]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNVLKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVET
RPTLGFQRVMQRAMVHTQSAGKAAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDEDEDDGNYSSDGMD
DDNENRTKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALAEGLAHQIVNGG
IPDALKDAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAKGS
LRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERFLP
DKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVARIPEKTVSHDDKQVLQFLGRDLKNMVYGQENAIDALVAAVK
MSRSGLALPDKPIGSFLFSGPTGVGKTEAAKQLAYSLGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAVNK
QPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKRERGDEMQAINKL
FTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHQLLDKKVEAEFTSALHKYLAEKGFDPQMGARPMHRLIQEKIRKP
LADELLFGKLSDGGFVRIDWDAAKEEAVLKFKKSKVKIKTASA

Nucleotide

• Length: 2292 bp

>NTDB_id=133441 DE10444_RS07230 WP_002223891.1 1398639..1400930(+) (clpC) [Neisseria meningitidis strain DE10444]
ATGCTTGCACCCGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCTCCGTGCCGAACGTCTTAAAACTCTGCGGCGCGGATTTGAAAG
TGGTGTCCGAACAGCTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGAACACCTTTTAGACACGGTCGAAACC
CGGCCCACGCTCGGCTTCCAACGCGTGATGCAACGGGCGATGGTGCATACCCAGTCTGCCGGAAAAGCCGCAGTCGAACC
GTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACACCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGACGATGGCAACTATTCTTCAGACGGCATGGAC
GACGATAATGAAAACCGCACCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGTCAAAGC
CGGCCGTATCGACCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTATGCCGCCGCCGCAAAAACA
ATCCGCTTTTGGTCGGCGAAGCGGGCGTGGGCAAAACCGCGCTGGCGGAAGGTTTGGCACATCAAATCGTCAACGGCGGC
ATTCCAGACGCGCTCAAAGATGCCGAAGTGTACGCGCTGGATATGGGCTCGCTGTTGGCGGGCACGAAATACCGCGGCGA
CTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTGTTTATCGACGAAATCCACA
CCATCATCGGCGCAGGCAGCACCAGCGGCGGCACCATGGACGCGTCCAACCTGCTCAAACCCGCGCTGGCAAAAGGTTCG
CTGCGCTGCATCGGCGCGACCACTTACGACGAATACCGCACCATTTTCGACAAAGACCACGCCTTAAGCCGCCGCTTCCA
AAAAATCGACGTGGTCGAACCCACCGTTTCCGAAACCGTACAAATCCTGCGCGGCTTGAAGCCGATGTTTGAAGCCTTCC
ACCAAGTCCGCTATACGCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCACGCTACATCAACGAGCGTTTCCTGCCC
GACAAAGCCATCGACGTGATGGACGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGTCATCGG
CAAAGCACAAATTGAAACCGTCATCGCCAAAGTTGCGCGGATTCCCGAAAAAACCGTGTCGCACGACGACAAACAAGTGC
TGCAATTCCTCGGTCGCGATTTGAAAAACATGGTTTACGGTCAAGAAAACGCCATCGACGCGCTGGTTGCCGCCGTCAAA
ATGTCGCGTTCCGGCCTTGCCCTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCGACCGGCGTGGGCAAAAC
CGAAGCCGCCAAACAGCTTGCCTACTCGCTGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAACGCCATG
CCGTATCGCGCCTCATCGGCGCGCCACCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTCAACAAA
CAGCCGCATTGCGTATTGCTCTTGGACGAAATCGAAAAAGCCCACCCCGACATTTTCAACGTCCTCCTGCAAGTCATGGA
CGCAGGCAAACTGACCGACAACAACGGCAAGAGTGCCGATTTCCGCAACGTCATCCTGATTATGACCACCAACGCAGGCG
CGGAAAGCCTCAGCCGCCCCAGCCTCGGCTTTACCGCCAAGCGCGAACGCGGCGACGAAATGCAGGCAATCAACAAGCTC
TTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATTATCCCGTTTGCACCCTTGTCCGAACCCATCATCGTCAAAGTCGT
GGACAAATTCCTGCTCCAGCTCGAACACCAGCTCCTCGACAAAAAAGTCGAAGCCGAATTCACGTCGGCATTGCACAAAT
ATCTGGCGGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGCAAACCG
CTCGCCGACGAACTCCTGTTCGGCAAACTATCCGACGGCGGCTTCGTGCGGATAGACTGGGATGCGGCAAAAGAAGAAGC
CGTGTTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCTCCGCATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (491-652)

• AAA lid domain (AAA_lid_9) (356-453)

• ATPase family associated with various cellular activities (AAA) (AAA) (216-348)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (658-738)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-61)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.65	100	0.413
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.725	94.233	0.393
clpC	Bacillus subtilis subsp. subtilis str. 168	37.221	100	0.393