Detailed information NTG0133419

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DE10444_RS04080
• Genome accession: NZ_CP012392
• Coordinates: 794549..797128 (-)
• Length: 859 a.a.
• NCBI ID: WP_002230685.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain DE10444
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 789549..802128

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DE10444_RS04060 (DE10444_0738)	-	790477..791742 (+)	1266	WP_002230693.1	Glu/Leu/Phe/Val family dehydrogenase	-
DE10444_RS04065 (DE10444_0739)	-	791800..792606 (-)	807	WP_002212946.1	DUF4198 domain-containing protein	-
DE10444_RS04070 (DE10444_0740)	-	792951..793160 (+)	210	WP_002212949.1	tautomerase family protein	-
DE10444_RS04075 (DE10444_0741)	-	793249..794463 (+)	1215	WP_002229658.1	pyridoxal phosphate-dependent aminotransferase	-
DE10444_RS04080 (DE10444_0742)	clpC	794549..797128 (-)	2580	WP_002230685.1	ATP-dependent chaperone ClpB	Regulator
DE10444_RS04085 (DE10444_0743)	trpS	797389..798399 (+)	1011	WP_002226234.1	tryptophan--tRNA ligase	-
DE10444_RS04090 (DE10444_0744)	-	798405..798746 (+)	342	WP_002220616.1	hypothetical protein	-
DE10444_RS04095 (DE10444_0745)	-	799068..799391 (+)	324	WP_002212957.1	Ag473 family lipoprotein	-
DE10444_RS04100 (DE10444_0746)	ppx	799600..801108 (-)	1509	WP_002237181.1	exopolyphosphatase	-
DE10444_RS04110 (DE10444_0747)	-	801224..801956 (-)	733	Protein_742	surface lipoprotein assembly modifier	-

Sequence

Protein

• Length: 859 a.a.
• Molecular weight: 95093.52 Da
• Isoelectric Point: 5.3090

>NTDB_id=133419 DE10444_RS04080 WP_002230685.1 794549..797128(-) (clpC) [Neisseria meningitidis strain DE10444]
MRYDKLTAKFQQALAEAQSLALAADGSYLEAGFVLKALLDDQNSGAAALLAHAGVNVPQVKQRLQQHLNSLPKVSGQGGD
ILPSRELQAVLNLMDKAATKRGDAYIASELFLLALVQQNDAAGKILKEAGATEQNINAAIDAVRGGQNVNDANAEDQRDA
LKKYTLDLTQRARDGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLRNKRLLVL
DLAALIAGAKYRGEFEERLKGVLNDLAKDDGNTLIFIDEIHTLVGAGKTDGAMDAGNMLKPALARGELHCIGATTLDEYR
QYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQERYEIHHGIDITDPAIVAAAELSDRYITDRFLPDKAIDLIDEAASR
VKMEKETKPEAMDKIDRRLIQLRMEKAHVEKEKDDASKKRLELIDEEINGLQKEYADLDEIWKAEKAISDGAANIKKQID
EVKIKIEQAKRQGDLALASKLMYEDLEHLEKQRAAAERADTDSTKPANKLLRNNVGAEEIAEVVSRMTGIPVSKMMEGER
DKLLKMEEVLHRRVVGQDEAVRAVSDAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKALAGFLFDSEDHLIRIDMSE
YMEKHAVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFKNTVIVM
TSNIGSQHIQQMGIQDYEAVKEVVMEDVKEHFRPEMINRIDEVVVFHGLDQANIRSIAKIQLKGLEKRLEKQNLRLTVSD
AALDIIAKAGFDPIYGARPLKRAIQSEIENPLAKALLAGNYAPESEIRVEADGDRLKFA

Nucleotide

• Length: 2580 bp

>NTDB_id=133419 DE10444_RS04080 WP_002230685.1 794549..797128(-) (clpC) [Neisseria meningitidis strain DE10444]
ATGCGATACGACAAATTAACCGCCAAATTCCAACAGGCCCTTGCAGAAGCTCAGAGTTTGGCGTTGGCTGCGGACGGCAG
CTATCTGGAAGCGGGCTTTGTGCTGAAAGCCCTGCTTGACGACCAAAACAGCGGTGCTGCCGCGCTCTTGGCTCATGCGG
GCGTGAACGTGCCGCAGGTGAAACAGCGTTTGCAGCAGCATTTGAACAGCCTGCCGAAAGTGTCCGGCCAGGGCGGCGAC
ATTCTGCCCAGCCGCGAATTGCAGGCGGTGTTGAACCTGATGGACAAAGCCGCAACCAAACGCGGCGATGCCTATATCGC
CAGTGAACTTTTCCTGCTTGCCTTGGTGCAGCAGAACGATGCGGCCGGCAAAATTTTGAAAGAAGCCGGCGCGACCGAAC
AAAACATCAATGCCGCGATTGACGCGGTACGAGGAGGACAAAACGTGAACGATGCCAATGCCGAAGACCAACGCGATGCT
TTGAAAAAATATACGCTCGATCTGACCCAACGCGCCCGAGACGGTAAGCTCGACCCCGTTATCGGCCGTGACGACGAAAT
CCGCCGTGCGATTCAGGTATTGCAACGCCGTACCAAAAACAACCCTGTGCTGATTGGCGAACCGGGCGTGGGTAAAACCG
CCATCGTCGAAGGTTTGGCACAACGCATCGTCAACGGCGAAGTACCCGAATCCCTGCGCAACAAACGCCTACTGGTTTTG
GACTTGGCGGCATTGATTGCCGGCGCGAAATACCGCGGCGAATTTGAAGAACGCTTGAAAGGCGTGTTGAACGACTTGGC
GAAAGACGACGGCAACACTCTGATTTTCATCGACGAAATCCATACTTTGGTCGGCGCAGGCAAAACCGACGGTGCGATGG
ATGCGGGCAATATGCTGAAACCGGCTTTGGCACGTGGCGAATTGCACTGTATCGGCGCGACCACCTTGGACGAATACCGC
CAATACATCGAAAAAGACGCGGCACTCGAACGCCGCTTCCAAAAAGTATTGGTTGGCGAGCCAAGTGTAGAAGACACCAT
CGCTATCTTGCGCGGTTTACAGGAGCGTTATGAAATCCACCACGGTATCGATATTACCGACCCTGCTATCGTTGCCGCAG
CGGAGTTGAGCGACCGCTACATTACCGACCGCTTCCTGCCTGATAAAGCGATTGATTTGATTGACGAAGCCGCCAGCCGT
GTCAAGATGGAAAAAGAAACCAAGCCGGAAGCAATGGACAAAATCGACCGCCGTCTAATTCAGCTTCGGATGGAAAAGGC
GCACGTTGAAAAAGAAAAAGACGATGCCAGCAAAAAACGTTTGGAACTGATAGACGAGGAAATCAACGGTCTGCAAAAAG
AATACGCCGATTTAGACGAAATCTGGAAAGCCGAAAAAGCAATTTCAGACGGTGCTGCTAATATTAAGAAACAAATTGAC
GAAGTCAAAATTAAAATCGAACAGGCAAAACGGCAAGGCGATTTGGCACTGGCTTCAAAATTGATGTATGAAGATTTGGA
GCATTTGGAAAAACAGCGTGCAGCCGCCGAACGGGCAGATACGGACAGCACAAAACCGGCAAACAAACTCTTGCGTAATA
ATGTCGGCGCAGAGGAAATCGCAGAGGTGGTTTCCCGTATGACCGGCATTCCCGTATCCAAAATGATGGAAGGCGAACGC
GACAAACTGCTGAAAATGGAAGAAGTATTGCACCGCCGCGTGGTCGGACAGGACGAAGCCGTGCGTGCCGTGTCCGACGC
TATCCGCCGCAGCCGCTCCGGTCTTGCCGATCCGAACAAGCCTTACGGCAGCTTCCTGTTCTTGGGCCCGACCGGCGTGG
GTAAAACCGAGTTGTGTAAAGCCCTGGCAGGCTTTCTGTTCGACAGCGAAGATCATCTGATTCGCATCGATATGTCCGAA
TATATGGAAAAACACGCCGTTGCACGCCTGATCGGTGCGCCTCCGGGCTATGTCGGCTACGAAGAAGGCGGCTACCTGAC
CGAACAAGTGCGCCGCAAACCGTACAGCGTGATTCTGCTGGACGAAGTGGAAAAAGCCCATCCCGATGTGTTCAACATCC
TGCTGCAAGTATTGGATGACGGTCGTTTGACCGACGGGCAAGGCAGGACGGTAGATTTTAAAAATACCGTGATTGTGATG
ACTTCCAACATCGGCAGCCAGCACATCCAACAAATGGGCATTCAGGATTACGAAGCGGTAAAAGAAGTTGTGATGGAGGA
TGTGAAAGAACATTTCCGTCCTGAAATGATCAACCGCATCGACGAAGTGGTCGTGTTCCACGGTTTGGATCAGGCAAACA
TCCGCAGCATTGCGAAAATCCAGCTCAAAGGTTTGGAAAAACGTTTGGAAAAACAAAACCTGCGCCTGACTGTTTCCGAT
GCCGCACTGGACATCATCGCCAAAGCCGGTTTCGACCCGATTTACGGCGCACGTCCGCTCAAACGCGCCATCCAGTCGGA
AATCGAAAACCCGCTGGCAAAAGCCCTGCTTGCCGGAAACTATGCGCCCGAAAGCGAAATCAGGGTAGAAGCCGACGGCG
ACAGACTGAAATTTGCCTGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (769-849)

• AAA domain (Cdc48 subfamily) (AAA_2) (601-763)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• AAA lid domain (AAA_lid_9) (342-442)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	43.902	100	0.44
clpC	Streptococcus pneumoniae TIGR4	39.203	100	0.412
clpC	Streptococcus pneumoniae Rx1	39.203	100	0.412
clpC	Streptococcus pneumoniae D39	39.203	100	0.412
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.504	100	0.402
clpC	Lactococcus lactis subsp. cremoris KW2	47.118	80.792	0.381
clpE	Streptococcus pneumoniae TIGR4	47.206	79.162	0.374