Detailed information NTG0133331

Bioinformatically predicted

Overview

• Name: kpsS
• Type: Regulator
• Locus tag: DE8669_RS00475
• Genome accession: NZ_CP012391
• Coordinates: 92438..93697 (+)
• Length: 419 a.a.
• NCBI ID: WP_002223278.1
• Uniprot ID: Q05014
• Organism: Neisseria meningitidis strain DE8669
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 87438..98697

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DE8669_RS00460 (DE8669_0085)	rfbA	88622..89497 (+)	876	WP_002218521.1	glucose-1-phosphate thymidylyltransferase RfbA	-
DE8669_RS00465 (DE8669_0086)	rfbC	89552..90091 (+)	540	WP_002218523.1	dTDP-4-dehydrorhamnose 3,5-epimerase	-
DE8669_RS00470 (DE8669_0087)	-	90253..92301 (+)	2049	WP_002223276.1	capsular polysaccharide biosynthesis protein	-
DE8669_RS00475 (DE8669_0088)	kpsS	92438..93697 (+)	1260	WP_002223278.1	capsule biosynthesis protein	Regulator
DE8669_RS00480 (DE8669_0089)	-	94064..95470 (+)	1407	WP_002223279.1	SEL1-like repeat protein	-
DE8669_RS00485 (DE8669_0090)	gltS	95688..96902 (+)	1215	WP_002216198.1	sodium/glutamate symporter	-
DE8669_RS00490 (DE8669_0091)	-	97001..98017 (+)	1017	WP_002223280.1	lysozyme inhibitor LprI family protein	-
DE8669_RS00495 (DE8669_0092)	-	98028..98225 (+)	198	WP_002218528.1	hypothetical protein	-
DE8669_RS13450	-	98243..98392 (+)	150	WP_014575095.1	hypothetical protein	-

Sequence

Protein

• Length: 419 a.a.
• Molecular weight: 48701.63 Da
• Isoelectric Point: 9.0748

>NTDB_id=133331 DE8669_RS00475 WP_002223278.1 92438..93697(+) (kpsS) [Neisseria meningitidis strain DE8669]
MKQTVLKNNLQNLLESAENILLLQGPVGDFFLRLADWLTANGKTVHKFNFNAGDDYFYPPTQAHTVVFNDNYDAFPEFLQ
EYITQHHIQAVVCFGDTRPYHVIAKRIANENQASFWAFEEGYFRPYYITLEKDGVNAFSPLPRRADFFLEQFPKLAQQEY
KAPTPVHGGFTPMAKNAIRYYIELFRNPRKYPDYIHHRAPNAGHYLKPWSLSILKRLNYYIEDIQIAKRVEAGKYGKFFI
VPLQVFNDSQVRIHCDFPSVRSFLLHVLSSFAEHAPADTNIIIKHHPMDRGFIDYWRDIKRFIKEHPELKGRVIYVHDVP
LPVFLRHGLGMVTINSTSGLSGLIHNMPVKVLGRAYYDIPGITDQNTLAEFWNHPTPPDKELFHAYRMYHLNVTQINGNF
YSQVFFPNKKTSNSSTPVI

Nucleotide

• Length: 1260 bp

>NTDB_id=133331 DE8669_RS00475 WP_002223278.1 92438..93697(+) (kpsS) [Neisseria meningitidis strain DE8669]
ATGAAACAGACCGTCCTCAAAAATAACCTGCAAAACCTGCTTGAAAGCGCAGAAAATATCCTGCTGCTTCAAGGCCCTGT
CGGCGATTTTTTTCTGCGCCTTGCCGACTGGCTGACTGCAAACGGCAAAACCGTACATAAATTCAACTTTAATGCAGGCG
ACGACTATTTTTATCCGCCCACTCAAGCGCATACCGTTGTTTTTAACGACAACTACGATGCCTTTCCTGAGTTTTTGCAA
GAATACATCACTCAACATCACATCCAGGCCGTTGTCTGCTTTGGCGACACACGCCCTTATCACGTCATTGCAAAACGCAT
TGCAAACGAAAACCAAGCCAGTTTCTGGGCGTTTGAAGAAGGCTATTTCCGCCCCTACTACATCACCTTAGAAAAAGACG
GCGTCAACGCATTTTCCCCGTTGCCGCGCCGTGCCGACTTTTTTCTTGAACAATTCCCTAAGCTTGCCCAGCAAGAATAT
AAAGCGCCAACGCCGGTACACGGCGGTTTTACGCCCATGGCAAAAAACGCTATCCGTTACTATATCGAGTTGTTCCGCAA
TCCACGCAAATACCCCGACTACATCCACCACCGCGCACCCAATGCCGGCCATTACCTCAAACCGTGGTCGCTCTCCATCC
TCAAGCGTTTGAACTACTATATTGAAGACATCCAAATCGCCAAACGTGTGGAAGCAGGCAAATACGGCAAGTTTTTTATT
GTTCCCTTACAGGTATTCAACGACAGCCAAGTCCGTATCCATTGCGACTTTCCCAGCGTCCGCAGCTTCCTGCTCCATGT
TTTGAGTTCATTTGCCGAGCACGCGCCTGCCGATACCAACATCATCATCAAGCATCATCCGATGGACCGCGGTTTTATCG
ACTACTGGCGCGACATTAAACGCTTTATCAAAGAACACCCCGAACTCAAAGGCCGCGTGATTTATGTCCATGATGTCCCC
CTGCCCGTTTTCCTGCGCCACGGTCTCGGCATGGTCACCATCAACAGCACCAGCGGCCTGTCCGGACTGATTCACAATAT
GCCAGTTAAGGTTCTCGGCCGTGCCTATTATGATATTCCCGGCATTACTGACCAAAATACCTTGGCAGAATTTTGGAATC
ATCCGACACCGCCTGACAAAGAGCTGTTCCATGCCTACCGAATGTACCACCTCAACGTGACCCAAATTAACGGCAACTTC
TACAGTCAGGTGTTTTTCCCCAACAAAAAAACCTCCAACTCTTCCACACCAGTAATCTGA

Domains

Predicted by InterProScan.

• Capsule polysaccharide biosynthesis protein (Capsule_synth) (89-401)

3D structure

• AlphaFold DB: Q05014

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
kpsS	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	38.579	94.033	0.363