Detailed information NTG0132896

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SSAL8618_RS03170
• Genome accession: NZ_CP009913
• Coordinates: 640032..642281 (-)
• Length: 749 a.a.
• NCBI ID: WP_038675577.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain NCTC 8618
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 635032..647281

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSAL8618_RS03140 (SSAL8618_03140)	-	635392..636012 (+)	621	WP_002890373.1	DUF3862 domain-containing protein	-
SSAL8618_RS03145 (SSAL8618_03145)	-	636095..636778 (+)	684	WP_002890375.1	TVP38/TMEM64 family protein	-
SSAL8618_RS03150 (SSAL8618_03150)	-	636756..637991 (+)	1236	WP_038675570.1	aminoacyltransferase	-
SSAL8618_RS03155 (SSAL8618_03155)	-	638089..639051 (+)	963	WP_038675572.1	Gfo/Idh/MocA family protein	-
SSAL8618_RS03160 (SSAL8618_03160)	-	639097..639399 (-)	303	WP_002885967.1	DUF1827 family protein	-
SSAL8618_RS03165 (SSAL8618_03165)	-	639409..639867 (-)	459	WP_038675574.1	NUDIX hydrolase	-
SSAL8618_RS03170 (SSAL8618_03170)	clpE	640032..642281 (-)	2250	WP_038675577.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SSAL8618_RS03175 (SSAL8618_03175)	argF	642524..643504 (+)	981	WP_038675579.1	ornithine carbamoyltransferase	-
SSAL8618_RS03180 (SSAL8618_03180)	-	643573..643803 (+)	231	WP_002885970.1	DUF1797 family protein	-
SSAL8618_RS03185 (SSAL8618_03185)	-	644117..644797 (+)	681	WP_002886081.1	amino acid ABC transporter permease	-
SSAL8618_RS03190 (SSAL8618_03190)	-	644797..645531 (+)	735	WP_002886191.1	amino acid ABC transporter ATP-binding protein	-
SSAL8618_RS03195 (SSAL8618_03195)	-	645703..646179 (+)	477	WP_037599232.1	ferrous iron transport protein A	-

Sequence

Protein

• Length: 749 a.a.
• Molecular weight: 83262.28 Da
• Isoelectric Point: 5.1477

>NTDB_id=132896 SSAL8618_RS03170 WP_038675577.1 640032..642281(-) (clpE) [Streptococcus salivarius strain NCTC 8618]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQNCYKIMKSDPENPLNQFNQTGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGNTQGPGRPGGPRQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGSVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAI
TAAAELSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
KQTIKDQDMPVITEKHIEAIVEQKTNIPVGDLKEKEQSQLLSLADDLKSHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEV
EKAHPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVLNQLGDFFSPEFMNRFD
GIIEFSALSKENLLTIVDLMLDNVNQRLANNGIHLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPN
EKDLKAVMTSKGHITIKSAKKSRKNCSES

Nucleotide

• Length: 2250 bp

>NTDB_id=132896 SSAL8618_RS03170 WP_038675577.1 640032..642281(-) (clpE) [Streptococcus salivarius strain NCTC 8618]
ATGCTCTGTCAAAACTGTAACCTTAATGAAGCTAGTATTCATTTGTATACCAATGTAAACGGTAATCAGCAACAAGTTGA
CCTCTGTCAAAATTGTTATAAAATCATGAAATCTGACCCAGAGAACCCCCTCAATCAATTCAATCAAACAGGAGGTTCAA
ACTTCTTCGATGATTTCTTCAGCGACCTAAATAACTTCCGTTCTTCTAACGGCGATCTTCCCAATACACCTCCAACACAA
GAAGGTGGTAACCGAGGAAACGGTGGCAATACACAAGGGCCAGGCCGTCCAGGAGGACCACGCCAACAAGCTCCTCAACA
GCCACAAGGTCTTCTTGAAGAGTTCGGCATTAACATCACTGACATCGCTCGTCGTGGAGACATTGATCCTGTTATTGGTC
GTGACGAGGAAATCATTCGTGTCATCGAAATTCTTAACCGCCGTACCAAGAACAACCCCGTCCTCATCGGTGAACCCGGT
GTCGGTAAGACTGCTGTTGTTGAAGGCCTAGCTCAAAAAATCGTTGACGGTAGCGTGCCACAAAAACTCCAAGGCAAACA
AGTCATCCGTCTTGATGTGGTCAGCCTGGTTCAAGGGACTGGTATTCGTGGCCAATTTGAAGAACGCATGCAAAAACTCA
TGGAAGAAATTCGTCAACGTCAGGATGTTATCCTATTTATTGATGAAATCCATGAAATCGTAGGAGCTGGTAATGCTGGT
GATGGCAATATGGATGCTGGAAACATCCTAAAACCTGCTCTTGCTCGTGGAGAACTTCAACTGGTCGGAGCAACAACACT
CAACGAATACCGCATCATCGAAAAAGATGCCGCCCTAGAGCGTCGTATGCAACCAGTTAAGGTTGACGAACCAACGGTTG
AGGAAACCATCACTATTTTGCGTGGTATTCAACCTAAATATCAGGACTACCACCACGTCAAATATACAGACGAAGCGATT
ACTGCAGCTGCAGAATTGTCCAACCGCTACATTCAAGACCGCTTCTTGCCAGACAAGGCCATCGACCTCCTCGATGAAGC
TGGTTCGAAGATGAATTTGACCCTCAATTTTGTTGATCCTAAAGATATCGACAAACGTTTGATTGAGGCTGAAAACCTCA
AGGCTCAAGCTACTCGTGACGAAGACTTTGAAAAAGCTGCCTATTTCCGTGATCAAATTGCCAAATACAAGGAAATGCAA
AAACAAACCATCAAAGACCAAGATATGCCTGTCATCACAGAAAAACATATCGAAGCCATTGTGGAACAAAAAACCAATAT
TCCTGTCGGTGATTTGAAAGAAAAAGAACAATCACAACTTCTTAGTCTTGCTGATGATCTTAAATCACATGTTATTGGAC
AAGATGCCGCAGTTGATAAGATTGCCAAAGCCATCCGCCGTAATCGTGTTGGATTGGGTGCACCAAATCGCCCAATTGGT
AGCTTCCTCTTCGTAGGTCCTACAGGAGTCGGTAAAACTGAACTCTCTAAACAATTGGCGATTGAACTCTTTGGTTCAGC
TGACAGTATGATTCGTTTCGACATGTCAGAATACATGGAAAAACACGCCGTTGCCAAATTAGTCGGTGCCCCTCCAGGAT
ATGTCGGTTACGACGAAGCTGGTCAGTTAACTGAAAAAGTCCGCCGTAATCCTTATTCACTCATTCTTCTGGATGAGGTT
GAAAAAGCTCACCCAGATGTTCTTCACATGTTCCTCCAAGTACTTGACGATGGTCGTTTGACTGATGGTCAAGGACGCAC
TGTAAGTTTCAAAGATACCATTATCATCATGACATCAAATGCTGGTACCGGTAAAGTTGAAGCTAGCGTCGGCTTTGGAG
CTGCCCGTGAAAATCGTACCAATTCTGTTCTTAACCAGCTTGGAGATTTCTTCAGCCCTGAATTTATGAACCGCTTTGAC
GGTATTATCGAATTCTCTGCCCTTAGCAAGGAAAATCTCCTTACTATCGTGGACCTCATGCTTGACAATGTCAACCAACG
CTTGGCTAACAACGGTATCCACCTCAGTGTAACCGATAAGGTTAAGGAGAAATTGGTTGACCTTGGTTATGATCCTAAGA
TGGGGGCTCGACCACTACGTCGTACCATCCAAGATCATATTGAAGATGCTATCACTGACTTCTACCTTGAAAATCCAAAC
GAAAAAGATCTCAAGGCAGTCATGACTTCAAAAGGTCACATCACCATTAAGTCTGCTAAAAAAAGCCGAAAAAACTGCTC
AGAAAGCTGA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (292-390)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (648-721)

• ATPase family associated with various cellular activities (AAA) (AAA) (154-274)

• AAA domain (Cdc48 subfamily) (AAA_2) (477-640)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	86.327	99.599	0.86
clpE	Streptococcus pneumoniae Rx1	83.489	100	0.837
clpE	Streptococcus pneumoniae D39	83.489	100	0.837
clpE	Streptococcus pneumoniae R6	83.489	100	0.837
clpE	Streptococcus pneumoniae TIGR4	83.489	100	0.837
clpC	Lactococcus lactis subsp. cremoris KW2	78.854	97.864	0.772
clpC	Bacillus subtilis subsp. subtilis str. 168	51.926	86.649	0.45
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.095	87.183	0.402
clpC	Streptococcus pneumoniae Rx1	47.36	83.445	0.395
clpC	Streptococcus pneumoniae D39	47.36	83.445	0.395
clpC	Streptococcus pneumoniae TIGR4	47.2	83.445	0.394
clpC	Streptococcus thermophilus LMD-9	47.04	83.445	0.393
clpC	Streptococcus thermophilus LMG 18311	46.72	83.445	0.39
clpC	Streptococcus mutans UA159	46.486	83.578	0.389