Detailed information NTG0131409

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: BF89_RS20440
• Genome accession: NZ_CP009700
• Coordinates: 3580993..3581787 (+)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis strain BA1035
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 3575993..3586787

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BF89_RS20425 (BF89_3823)	argR	3576832..3577281 (+)	450	WP_001032581.1	arginine repressor ArgR	-
BF89_RS20430 (BF89_3824)	recN	3577549..3579288 (+)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
BF89_RS20435 (BF89_3825)	spoIVB	3579407..3580705 (+)	1299	WP_003172258.1	SpoIVB peptidase	-
BF89_RS20440 (BF89_3826)	spo0A	3580993..3581787 (+)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
BF89_RS20445 (BF89_3827)	-	3582085..3583611 (+)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
BF89_RS20450 (BF89_3828)	-	3583779..3583925 (-)	147	WP_001247671.1	YycC family protein	-
BF89_RS20455 (BF89_3829)	-	3583976..3584704 (+)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
BF89_RS20460 (BF89_3830)	-	3584753..3584986 (-)	234	WP_001190187.1	DUF2627 domain-containing protein	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=131409 BF89_RS20440 WP_003161566.1 3580993..3581787(+) (spo0A) [Bacillus anthracis strain BA1035]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=131409 BF89_RS20440 WP_003161566.1 3580993..3581787(+) (spo0A) [Bacillus anthracis strain BA1035]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818