Detailed information NTG0131179

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ADJ80_RS01530
• Genome accession: NZ_CP012067
• Coordinates: 309004..311574 (+)
• Length: 856 a.a.
• NCBI ID: WP_050692667.1
• Uniprot ID: -
• Organism: Aggregatibacter aphrophilus strain W10433
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 304004..316574

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ADJ80_RS01500 (ADJ80_01505)	tusA	304104..304343 (+)	240	WP_050692662.1	sulfurtransferase TusA	-
ADJ80_RS01505 (ADJ80_01510)	ubiK	304372..304620 (+)	249	WP_005702113.1	ubiquinone biosynthesis accessory factor UbiK	-
ADJ80_RS01510 (ADJ80_01515)	nadR	304705..305976 (+)	1272	WP_050692663.1	multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR	-
ADJ80_RS01515 (ADJ80_01520)	-	305993..306676 (+)	684	WP_050692664.1	metallophosphoesterase family protein	-
ADJ80_RS01520 (ADJ80_01525)	-	306780..308009 (+)	1230	WP_050692665.1	aromatic amino acid transporter	-
ADJ80_RS01525 (ADJ80_01530)	-	308102..308758 (-)	657	WP_050692666.1	helix-hairpin-helix domain-containing protein	-
ADJ80_RS01530 (ADJ80_01535)	clpC	309004..311574 (+)	2571	WP_050692667.1	ATP-dependent chaperone ClpB	Regulator
ADJ80_RS01535 (ADJ80_01540)	-	311672..312169 (-)	498	WP_050692668.1	surface-adhesin E family protein	-
ADJ80_RS01540 (ADJ80_01545)	purM	312352..313392 (+)	1041	WP_050694154.1	phosphoribosylformylglycinamidine cyclo-ligase	-
ADJ80_RS01545 (ADJ80_01550)	purN	313392..314030 (+)	639	WP_050692669.1	phosphoribosylglycinamide formyltransferase	-
ADJ80_RS01550 (ADJ80_01555)	-	314071..314886 (-)	816	WP_050692670.1	Cof-type HAD-IIB family hydrolase	-
ADJ80_RS01555 (ADJ80_01560)	-	315043..315729 (+)	687	WP_050692671.1	DNA utilization protein GntX	-
ADJ80_RS01560 (ADJ80_01565)	nfuA	315842..316426 (+)	585	WP_050694155.1	Fe-S biogenesis protein NfuA	-

Sequence

Protein

• Length: 856 a.a.
• Molecular weight: 95650.16 Da
• Isoelectric Point: 5.2020

>NTDB_id=131179 ADJ80_RS01530 WP_050692667.1 309004..311574(+) (clpC) [Aggregatibacter aphrophilus strain W10433]
MNIEKFTTKFQQAIAEAQSLAIGKDNQFIEPVHLLSALLNQQDGSVAPILTASGVNVAVLRNELNNELAKLPQVSGNGGD
VQLSRQLLNILNLCDKLAQQRQDKFISSELFLLAALEEKGAVSEILKKCGAKKEQILQAIDHIRGGQNVNDQNAEESRQA
LEKYTIDLTARAESGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSL
DMGALIAGAKYRGEFEERLKAVLKELAQEEGRVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVGEPSVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASS
IRMEIDSKPQPLDCLDRRIIQLKLEQQALQKEDDDASRKRLEMLEKELAEKEREYAELEEVWKSEKAALSGTQHIKAELE
NARTQMEQARRAGDLSKMSELQYGKIPELEKQLAAAEGAEGKEMSLLRYRVTDEEIAEVLSRATGIPVSKMMEGEKEKLL
RMEEELHKRVIGQNEAVDAVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLAKFLFDSEDAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHHDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQGNQEESYDDMKALVMSVVSQHFRPEFINRIDETVVFHPLNKDNIRAIAEIQLKRLINRMESRGYVLHFTDTTLN
FISEIGYDPIYGARPLKRAIQQEIENPLAQQILSGSLLPEKPISVDYVDGKIVAKQ

Nucleotide

• Length: 2571 bp

>NTDB_id=131179 ADJ80_RS01530 WP_050692667.1 309004..311574(+) (clpC) [Aggregatibacter aphrophilus strain W10433]
ATGAATATTGAAAAATTTACTACCAAATTCCAACAAGCCATTGCTGAAGCGCAATCTTTGGCGATTGGCAAAGATAATCA
ATTTATTGAACCGGTACATTTATTGAGCGCGTTGTTAAATCAACAAGACGGCTCCGTGGCGCCGATTTTAACCGCAAGCG
GCGTGAACGTTGCCGTGTTGCGCAATGAACTCAACAACGAACTTGCCAAACTTCCGCAAGTGTCCGGCAATGGCGGTGAT
GTACAACTTTCCCGTCAGTTGCTTAACATATTGAATTTATGCGACAAATTGGCACAACAACGGCAGGATAAATTTATTTC
CTCCGAACTCTTTTTACTTGCCGCCTTAGAAGAAAAAGGCGCCGTCAGTGAGATACTGAAAAAGTGCGGTGCGAAAAAAG
AACAAATTTTACAAGCCATCGATCATATTCGTGGAGGACAAAACGTGAATGATCAAAACGCGGAAGAAAGCCGCCAAGCC
TTAGAAAAATATACTATCGACTTAACCGCCCGTGCGGAAAGTGGCAAATTGGATCCGGTGATTGGGCGTGATGAAGAAAT
TCGCCGCACCATTCAAGTATTGCAACGCCGCACCAAAAACAATCCGGTGCTTATCGGTGAACCGGGCGTGGGTAAAACCG
CCATTGTGGAAGGGTTGGCACAGCGTATTGTGAATGGCGAAGTGCCGGAAGGTTTGAAAAATAAACGCGTGCTTTCACTT
GATATGGGGGCGTTAATCGCCGGGGCAAAATATCGCGGTGAATTTGAAGAACGCCTGAAAGCCGTCTTGAAAGAATTAGC
GCAGGAAGAAGGCCGCGTCATTTTATTCATTGATGAAATTCACACCATGGTGGGTGCGGGTAAAACCGATGGCGCCATGG
ATGCGGGCAACTTGTTAAAACCAAGTTTGGCACGCGGTGAATTGCATTGTGTGGGCGCGACCACATTAGACGAATACCGC
CAATACATTGAGAAAGATGCGGCACTTGAACGTCGTTTCCAAAAAGTGTTTGTGGGTGAACCGAGTGTGGAAGACACCAT
CGCCATTTTGCGCGGCTTAAAAGAACGTTATGAAATCCATCACCACGTGCAAATTACCGACCCGGCTATCGTGGCAGCGG
CAACATTGTCTCATCGTTACATTTCCGATCGCCAGTTACCGGATAAAGCCATCGACTTGATCGACGAAGCCGCATCCAGC
ATTCGGATGGAAATCGACTCCAAACCACAGCCGTTGGATTGCTTGGATCGCCGTATTATCCAACTCAAATTGGAACAACA
GGCGTTACAAAAAGAAGATGACGATGCCAGCCGCAAACGCTTGGAGATGTTAGAAAAAGAATTAGCGGAAAAAGAACGGG
AATACGCTGAATTAGAAGAAGTTTGGAAATCCGAAAAAGCCGCGCTTTCGGGCACCCAACACATTAAAGCTGAATTGGAA
AACGCCCGTACCCAAATGGAACAAGCCCGTCGTGCCGGTGATTTGAGCAAAATGTCCGAATTGCAATACGGTAAAATTCC
GGAATTGGAAAAACAATTAGCGGCAGCAGAAGGTGCGGAAGGCAAAGAAATGAGCCTATTACGCTATCGTGTTACCGACG
AGGAAATTGCTGAAGTGCTTTCCCGTGCCACCGGCATTCCGGTCTCCAAAATGATGGAAGGCGAAAAAGAAAAACTCTTG
CGCATGGAAGAAGAATTGCACAAACGGGTTATCGGGCAAAACGAAGCCGTGGATGCTGTGGCGAATGCCATTCGTCGTAG
CCGTGCCGGTCTTTCTGATCCGAATCGCCCGATTGGTTCCTTCTTGTTCTTAGGACCAACCGGTGTGGGTAAAACCGAAT
TGTGCAAAACCTTGGCGAAATTCTTGTTTGATAGCGAAGATGCCATGGTGCGTATCGACATGTCCGAATTCATGGAAAAA
CACAGCGTGTCCCGCTTGGTCGGTGCACCTCCGGGCTATGTGGGCTATGAAGAAGGTGGTTATTTAACCGAGGCTGTGCG
TCGTCGTCCGTATTCCGTGATTTTGCTCGACGAAGTGGAAAAAGCGCACCACGATGTATTCAACATCTTGTTGCAAGTGT
TGGATGATGGCCGTTTAACCGACGGACAAGGCAGAACCGTGGATTTCCGCAATACGGTGGTGATCATGACGTCTAACTTG
GGTTCCGATTTGATTCAAGGCAACCAAGAAGAAAGCTACGACGACATGAAAGCGTTAGTGATGTCTGTGGTGAGCCAACA
TTTCCGTCCGGAATTTATTAACCGAATTGACGAAACCGTGGTGTTCCATCCGTTGAATAAAGACAACATTCGCGCCATTG
CGGAAATTCAGTTAAAACGCTTAATCAACCGCATGGAAAGCCGTGGCTATGTGTTGCACTTTACTGATACCACCCTCAAT
TTCATTAGCGAAATCGGCTATGACCCGATTTACGGCGCGCGCCCATTAAAACGTGCAATTCAGCAAGAAATTGAGAACCC
GTTAGCGCAACAAATCCTTTCCGGCAGTTTGTTACCGGAAAAACCGATTAGCGTGGATTATGTTGACGGCAAAATTGTGG
CAAAACAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (765-843)

• AAA lid domain (AAA_lid_9) (342-443)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-336)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.835	100	0.475
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.2	100	0.442
clpE	Streptococcus mutans UA159	49.269	79.907	0.394
clpE	Streptococcus pneumoniae TIGR4	48.971	79.439	0.389
clpE	Streptococcus pneumoniae D39	48.827	79.673	0.389
clpE	Streptococcus pneumoniae Rx1	48.827	79.673	0.389
clpE	Streptococcus pneumoniae R6	48.827	79.673	0.389
clpC	Lactococcus lactis subsp. cremoris KW2	46.089	83.645	0.386