Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   NG74_RS14575 Genome accession   NZ_CP009679
Coordinates   3036883..3037527 (-) Length   214 a.a.
NCBI ID   WP_014418762.1    Uniprot ID   A0A2Z4EIP2
Organism   Bacillus velezensis strain JS25R     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3031883..3042527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NG74_RS14540 (NG74_03018) - 3033068..3033499 (+) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -
  NG74_RS14545 (NG74_03019) - 3033499..3033840 (+) 342 WP_022553706.1 Na(+)/H(+) antiporter subunit C -
  NG74_RS14550 (NG74_03020) - 3033833..3035314 (+) 1482 WP_022553707.1 Na+/H+ antiporter subunit D -
  NG74_RS14555 (NG74_03021) - 3035320..3035796 (+) 477 WP_022553708.1 Na+/H+ antiporter subunit E -
  NG74_RS14560 (NG74_03022) - 3035796..3036080 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  NG74_RS14565 (NG74_03023) mnhG 3036064..3036438 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  NG74_RS14570 (NG74_03024) - 3036478..3036861 (-) 384 WP_014418761.1 hotdog fold thioesterase -
  NG74_RS14575 (NG74_03025) comA 3036883..3037527 (-) 645 WP_014418762.1 response regulator transcription factor Regulator
  NG74_RS14580 (NG74_03026) comP 3037608..3039899 (-) 2292 WP_022553709.1 histidine kinase Regulator
  NG74_RS14585 (NG74_03027) comX 3039911..3040075 (-) 165 WP_007613432.1 competence pheromone ComX -
  NG74_RS14590 (NG74_03028) - 3040075..3040986 (-) 912 WP_022553710.1 polyprenyl synthetase family protein -
  NG74_RS14595 (NG74_03029) degQ 3041138..3041278 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  NG74_RS14600 (NG74_03030) - 3041744..3042085 (+) 342 WP_014418765.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24302.70 Da        Isoelectric Point: 4.9953

>NTDB_id=131098 NG74_RS14575 WP_014418762.1 3036883..3037527(-) (comA) [Bacillus velezensis strain JS25R]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTQRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=131098 NG74_RS14575 WP_014418762.1 3036883..3037527(-) (comA) [Bacillus velezensis strain JS25R]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTTCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACACAGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z4EIP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

85.981

100

0.86

Multiple sequence alignment