Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EP23_RS18125 Genome accession   NZ_CP009623
Coordinates   1184293..1185015 (+) Length   240 a.a.
NCBI ID   WP_060551492.1    Uniprot ID   -
Organism   Staphylococcus agnetis strain 908     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1179293..1190015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EP23_RS24670 - 1179472..1180635 (-) 1164 WP_060551487.1 hypothetical protein -
  EP23_RS18105 (EP23_05985) - 1180806..1181603 (+) 798 WP_060551488.1 carbon-nitrogen family hydrolase -
  EP23_RS18110 (EP23_05990) - 1182251..1182814 (+) 564 WP_060551489.1 accessory gene regulator AgrB -
  EP23_RS18115 (EP23_12525) agrD 1182817..1182951 (+) 135 WP_060551490.1 cyclic lactone autoinducer peptide AgrD -
  EP23_RS18120 (EP23_05995) agrC 1182981..1184279 (+) 1299 WP_060551491.1 quorum-sensing sensor histidine kinase AgrC -
  EP23_RS18125 (EP23_06000) agrA 1184293..1185015 (+) 723 WP_060551492.1 quorum-sensing response regulator AgrA Regulator
  EP23_RS18130 (EP23_06005) - 1185082..1186572 (-) 1491 WP_060551493.1 sucrose-6-phosphate hydrolase -
  EP23_RS18135 (EP23_06010) - 1186925..1187152 (-) 228 WP_060551494.1 sulfurtransferase TusA family protein -
  EP23_RS18140 (EP23_06015) - 1187175..1188260 (-) 1086 WP_060551495.1 YeeE/YedE family protein -
  EP23_RS18145 (EP23_06020) - 1188443..1189078 (-) 636 WP_037567012.1 redox-sensing transcriptional repressor Rex -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28238.40 Da        Isoelectric Point: 5.2269

>NTDB_id=130835 EP23_RS18125 WP_060551492.1 1184293..1185015(+) (agrA) [Staphylococcus agnetis strain 908]
MKILICEDDPKQRERMESIIQNYIMIEEKPMEIEISTSDPYALLEASKNMTDIGCYFLDIQLESDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKLAAMDFIFKDDIDELRTRIIDCLETALKRLDLLTKDNTVETMELKQGSNSVYVNYDDVM
FFESSPKSHRLIAHLDNRQIEFYGNLRELAQIDGRFFRCHNSFVLNRYNITHVDAKERIVYFKNDEFCYVSVRNIKKIKK

Nucleotide


Download         Length: 723 bp        

>NTDB_id=130835 EP23_RS18125 WP_060551492.1 1184293..1185015(+) (agrA) [Staphylococcus agnetis strain 908]
TTGAAAATTTTAATTTGTGAGGATGACCCTAAACAAAGAGAACGAATGGAATCCATCATTCAGAATTACATTATGATTGA
AGAAAAGCCTATGGAAATTGAAATTTCTACTAGTGACCCCTATGCGTTACTTGAGGCATCCAAAAATATGACTGATATTG
GTTGTTATTTTTTAGACATCCAATTGGAATCAGATATTAATGGTATTAAGCTTGGTAGCGAAATTCGAAAACATGATCCT
GTAGGTAATATTATTTTTGTAACCAGTCATAGTGAATTAACCTATTTAACTTTCGTGTATAAACTTGCAGCAATGGATTT
TATTTTTAAAGATGACATTGATGAGTTACGTACGAGAATTATTGATTGTCTCGAAACAGCACTTAAGCGGTTAGATTTAT
TAACAAAAGATAACACAGTAGAAACAATGGAATTAAAACAAGGCAGTAATTCTGTCTATGTTAACTATGATGATGTTATG
TTTTTTGAATCTTCACCTAAATCACATCGTTTGATTGCACATTTAGATAATCGGCAAATTGAATTTTATGGTAATTTAAG
AGAGCTCGCACAAATTGATGGTCGTTTTTTTAGATGTCATAATAGTTTTGTGTTAAATCGATATAACATTACGCATGTTG
ATGCTAAAGAGCGCATTGTTTATTTTAAAAATGATGAATTTTGCTATGTGTCTGTAAGAAATATAAAAAAAATCAAAAAA
TAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

81.513

99.167

0.808

Multiple sequence alignment