Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   NF38_RS03890 Genome accession   NZ_CP009610
Coordinates   761506..762198 (+) Length   230 a.a.
NCBI ID   WP_038440789.1    Uniprot ID   A0AAJ8WR53
Organism   Haemophilus influenzae strain Hi375     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 756506..767198
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NF38_RS03870 (NF38_03870) ampD 757778..758338 (-) 561 WP_011271974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  NF38_RS03875 (NF38_03875) pilA 758453..758902 (+) 450 WP_011271973.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  NF38_RS03880 (NF38_03880) pilB 758899..760296 (+) 1398 WP_038440787.1 GspE/PulE family protein Machinery gene
  NF38_RS03885 (NF38_03885) pilC 760289..761509 (+) 1221 WP_011271971.1 type II secretion system F family protein Machinery gene
  NF38_RS03890 (NF38_03890) pilD 761506..762198 (+) 693 WP_038440789.1 A24 family peptidase Machinery gene
  NF38_RS03895 (NF38_03895) rho 762252..763514 (-) 1263 WP_005629550.1 transcription termination factor Rho -
  NF38_RS03900 (NF38_03900) metJ 763762..764079 (+) 318 WP_038440791.1 met regulon transcriptional regulator MetJ -
  NF38_RS03905 (NF38_03905) cueR 764093..764479 (-) 387 WP_005663006.1 Cu(I)-responsive transcriptional regulator -
  NF38_RS03910 (NF38_03910) - 764556..764762 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  NF38_RS03915 (NF38_03915) - 764837..765043 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  NF38_RS03920 (NF38_03920) - 765118..765324 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  NF38_RS03925 (NF38_03925) - 765398..765604 (+) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26786.77 Da        Isoelectric Point: 8.6895

>NTDB_id=130699 NF38_RS03890 WP_038440789.1 761506..762198(+) (pilD) [Haemophilus influenzae strain Hi375]
MIYFTMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNSSPFQPHFASIQQKKCGHILRYFFSIGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGTDNNFSLLTLSESIKSAAIFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHRKKKEFLPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=130699 NF38_RS03890 WP_038440789.1 761506..762198(+) (pilD) [Haemophilus influenzae strain Hi375]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACAGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTTAGTATTGGGGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGCACAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTATTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAGAAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

97.391

100

0.974
  pilD Haemophilus influenzae Rd KW20

95.652

100

0.957

Multiple sequence alignment