Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   lpt_RS02385 Genome accession   NZ_CP012019
Coordinates   528474..531329 (+) Length   951 a.a.
NCBI ID   WP_042754756.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila strain Toronto-20052     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 523474..536329
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  lpt_RS02360 (lpt_02345) - 524275..525729 (-) 1455 WP_010946128.1 RimK family protein -
  lpt_RS02365 (lpt_02350) - 525733..526446 (-) 714 WP_011213037.1 C39 family peptidase -
  lpt_RS02370 (lpt_02355) - 526641..527114 (-) 474 WP_010946130.1 PaaI family thioesterase -
  lpt_RS02375 (lpt_02360) - 527111..527662 (-) 552 WP_042754758.1 BON domain-containing protein -
  lpt_RS02380 (lpt_02365) - 527921..528379 (-) 459 WP_042754757.1 hypothetical protein -
  lpt_RS02385 (lpt_02370) uvrA 528474..531329 (+) 2856 WP_042754756.1 excinuclease ABC subunit UvrA Machinery gene
  lpt_RS02390 (lpt_02375) - 531512..532093 (+) 582 WP_010946134.1 LemA family protein -
  lpt_RS02395 (lpt_02380) htpX 532104..533123 (+) 1020 WP_011213042.1 zinc metalloprotease HtpX -
  lpt_RS02400 (lpt_02385) - 533150..533923 (-) 774 WP_010946136.1 ABC transporter permease -
  lpt_RS02405 (lpt_02390) - 533913..534827 (-) 915 WP_042754755.1 ABC transporter ATP-binding protein -
  lpt_RS02410 (lpt_02395) vipA 535058..536116 (-) 1059 WP_027219148.1 Dot/Icm T4SS effector VipA -

Sequence

Protein


Download         Length: 951 a.a.        Molecular weight: 105498.23 Da        Isoelectric Point: 6.8834

>NTDB_id=130696 lpt_RS02385 WP_042754756.1 528474..531329(+) (uvrA) [Legionella pneumophila subsp. pneumophila strain Toronto-20052]
MHTITIRGARTHNLKNLDLELPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSMMEKPDVDSIEGLS
PAISIEQKATSHNPRSTVGTITEIYDYLRLLYARVGEPRCPTHHTSLHAQTISQMVDQVLALPEDSKVMILAPVIRERKG
EHVQFLQQLQAQGYVRARIDGELYELDSPPKLGLRTKHTIEVVIDRFKVRPDLAQRLSESFENALNLADGLAIVSSMDGH
FKELLFSSRFACSECGYSLSELEPRLFSFNNPVGACSSCDGLGVDQFFDPSRVVHDATASLAEGAIRGWDRKTTYYFSML
ESLARHYGFDTSTPFCDLSEAMQQIVLYGSGREIIEFQYHRPHGGYMVKRHSFEGIIPNMQRRYRESDSGMIREELAKYL
SSRPCQSCQGARLREEARHVFIDNKNLPEITSYSIEQAYQFFKELKLSGYRGEIAAKINKEIVERLGFLVNVGLDYLSLA
RSAETLSGGEAQRIRLASQIGSGLVGVMYILDEPSIGLHQRDNDRLLSTLMHLRNQGNTVIVVEHDEDAIRSADFVLDIG
PGAGVHGGEVVASGSPEEVMKNPASLTGQYLSGKKEIEIPKNRIPVNHDRMIHLKGVSCNNLQNVDVSIPLGLLTCITGV
SGSGKSSLINDTLYPIAANALNRASLMTIGEVKDISGLHLCDKVIDIDQSPIGRTPRSNPATYTGLFTHIRDLFSGTPES
RARGYQPGRFSFNVKGGRCEACQGDGLIKVEMHFLPDIYVSCDVCQGKRYNRETLEIHYKGKNIHEVLDMTVEDACAFFA
AIPVIARKCQTLMDVGLSYIKLGQSATTLSGGEAQRIKLARELSKRDTGNTLYILDEPTTGLHFHDTKQLLTVLTRLREQ
GNTIVIIEHNLDVIKTADWIVDLGPEGGSKGGKIIATGTPEMVAENSRSFTGQFLKQILSKSNELLLQKCK

Nucleotide


Download         Length: 2856 bp        

>NTDB_id=130696 lpt_RS02385 WP_042754756.1 528474..531329(+) (uvrA) [Legionella pneumophila subsp. pneumophila strain Toronto-20052]
ATGCATACCATCACCATTCGTGGCGCAAGAACCCATAATCTCAAGAACTTGGACCTGGAGCTTCCTCGAGATAAATTAAT
CGTAATAACCGGATTGTCTGGTTCTGGGAAGTCGTCTTTAGCTTTTGATACTCTCTATGCCGAAGGCCAGCGCCGTTACG
TGGAATCTTTGTCTGCTTATGCTCGACAATTTTTGTCCATGATGGAAAAACCTGATGTTGATTCGATAGAGGGGCTATCC
CCGGCGATTTCTATAGAACAAAAGGCTACCTCTCATAATCCCCGATCTACGGTAGGCACCATTACCGAAATTTATGACTA
TTTGCGCTTGCTTTATGCCCGAGTCGGAGAGCCAAGGTGTCCTACCCACCACACCAGCTTGCATGCTCAGACCATTAGCC
AAATGGTTGACCAGGTATTGGCTTTACCAGAAGACAGTAAAGTGATGATTCTGGCGCCTGTTATTCGTGAACGGAAGGGA
GAGCATGTCCAGTTTTTGCAACAATTGCAAGCGCAGGGGTATGTACGTGCACGCATTGATGGAGAGCTTTATGAACTGGA
TTCTCCCCCTAAATTAGGATTGCGCACCAAGCACACTATTGAAGTAGTTATTGATCGTTTTAAAGTGCGCCCTGATTTGG
CTCAACGTTTGAGTGAATCTTTTGAAAATGCGCTCAATCTGGCAGATGGCCTTGCCATCGTTTCTTCAATGGATGGCCAT
TTCAAGGAACTTTTATTTTCTTCCAGGTTTGCATGCTCTGAATGCGGTTACAGTTTAAGTGAACTTGAGCCAAGGCTTTT
TTCATTTAACAATCCTGTCGGTGCGTGTTCCTCATGTGATGGGCTTGGAGTGGATCAGTTTTTTGATCCGTCAAGAGTAG
TCCACGATGCAACCGCTAGTTTGGCAGAAGGGGCAATCAGGGGATGGGATAGGAAAACCACGTATTATTTCAGCATGCTT
GAGTCGCTTGCGAGGCACTATGGTTTTGATACCAGTACGCCTTTTTGTGATTTAAGTGAAGCAATGCAACAAATCGTTTT
GTATGGTAGTGGTCGTGAAATAATCGAGTTTCAGTATCATAGGCCGCATGGAGGATACATGGTGAAGCGGCATAGTTTTG
AGGGAATAATTCCTAACATGCAACGCCGCTATCGTGAATCAGATTCTGGTATGATAAGGGAGGAACTTGCCAAATACCTA
TCCTCACGCCCTTGCCAATCTTGTCAGGGAGCGAGATTACGTGAAGAAGCTCGACATGTATTTATTGATAATAAAAATCT
ACCAGAAATCACCAGCTATTCTATTGAGCAAGCCTATCAGTTTTTTAAAGAGCTGAAGTTATCGGGATATAGGGGTGAAA
TTGCAGCAAAAATCAATAAGGAAATTGTCGAGCGGCTGGGGTTTCTGGTGAATGTCGGGCTGGATTATTTGTCTTTGGCT
CGAAGCGCGGAGACTCTATCTGGCGGAGAAGCTCAACGTATTCGCCTGGCTAGTCAAATAGGTTCAGGGCTTGTAGGGGT
GATGTATATTTTGGATGAGCCTTCAATAGGGCTGCACCAACGTGACAACGACCGATTATTGAGTACTTTAATGCATTTAC
GCAACCAGGGGAATACTGTAATCGTTGTGGAACATGATGAAGATGCTATCCGAAGCGCTGATTTTGTTCTTGATATAGGG
CCTGGGGCTGGAGTGCATGGTGGGGAAGTAGTTGCCAGCGGTTCTCCTGAAGAGGTAATGAAAAACCCCGCATCTCTCAC
CGGCCAATATTTGTCTGGGAAAAAGGAAATAGAAATTCCCAAGAATCGAATTCCGGTTAACCATGATCGGATGATTCATT
TAAAAGGCGTGTCTTGCAATAATTTACAAAATGTTGATGTCAGTATTCCTTTAGGTTTGTTGACTTGTATTACAGGTGTT
TCTGGTTCAGGTAAATCCAGTTTAATTAATGATACTTTATATCCTATTGCTGCCAATGCACTAAACAGAGCCAGCTTAAT
GACTATAGGTGAGGTTAAGGACATTTCTGGACTGCATCTTTGTGACAAGGTTATTGACATCGATCAGAGCCCAATTGGCA
GAACTCCGCGTTCCAATCCGGCAACTTATACTGGTTTATTTACTCATATCAGAGATTTATTCTCAGGGACTCCGGAATCA
AGAGCACGAGGGTATCAACCTGGGCGCTTTAGTTTCAATGTAAAAGGTGGCCGGTGCGAAGCTTGTCAAGGTGATGGTCT
TATCAAGGTTGAAATGCATTTTTTACCTGATATATACGTTTCTTGCGATGTATGCCAAGGCAAAAGATACAATAGGGAAA
CTTTGGAAATTCACTACAAAGGCAAAAATATTCATGAAGTGTTGGACATGACTGTCGAAGATGCGTGCGCTTTTTTTGCT
GCCATTCCTGTTATTGCCAGAAAATGCCAAACATTAATGGATGTCGGTTTGTCTTATATAAAGCTTGGACAAAGTGCAAC
TACTCTCTCTGGAGGAGAAGCTCAAAGGATCAAGTTGGCCAGAGAATTATCAAAAAGGGATACCGGAAATACACTGTATA
TTCTTGATGAGCCCACAACAGGATTACACTTTCATGACACGAAACAGTTATTAACTGTGTTGACTCGCTTACGAGAGCAA
GGAAATACCATTGTCATTATTGAACATAATTTGGATGTGATAAAAACGGCTGATTGGATCGTTGATCTTGGCCCTGAAGG
AGGCAGTAAAGGAGGAAAGATTATTGCAACAGGAACCCCCGAAATGGTTGCTGAAAACTCTCGTTCTTTTACAGGTCAGT
TTTTAAAACAAATTTTATCAAAATCAAATGAGCTTCTATTGCAGAAATGCAAATAG

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(289-398)

UvrA interaction domain (UvrA_inter)

(130-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

58.698

98.528

0.578
  uvrA Streptococcus pneumoniae TIGR4

58.698

98.528

0.578
  uvrA Streptococcus pneumoniae D39

58.698

98.528

0.578

Multiple sequence alignment