Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   NF38_RS00265 Genome accession   NZ_CP009610
Coordinates   55873..56556 (-) Length   227 a.a.
NCBI ID   WP_011272301.1    Uniprot ID   Q4QLW8
Organism   Haemophilus influenzae strain Hi375     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 50873..61556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NF38_RS00250 (NF38_00250) nrdR 51678..52127 (-) 450 WP_005648026.1 transcriptional regulator NrdR -
  NF38_RS00255 (NF38_00255) recC 52182..55547 (-) 3366 WP_011272303.1 exodeoxyribonuclease V subunit gamma -
  NF38_RS00260 (NF38_00260) comQ 55593..55880 (-) 288 WP_021034778.1 DUF5374 domain-containing protein Machinery gene
  NF38_RS00265 (NF38_00265) comP 55873..56556 (-) 684 WP_011272301.1 DUF2572 family protein Machinery gene
  NF38_RS00270 (NF38_00270) comO 56553..57272 (-) 720 WP_011272300.1 type II secretion system protein J Machinery gene
  NF38_RS00275 (NF38_00275) comN 57272..57784 (-) 513 WP_011272299.1 type II secretion system protein Machinery gene
  NF38_RS00280 (NF38_00280) suhB 57984..58796 (+) 813 WP_011272298.1 inositol-1-monophosphatase -
  NF38_RS00285 (NF38_00285) nrfE 58905..60812 (+) 1908 WP_038440290.1 heme lyase NrfEFG subunit NrfE -
  NF38_RS00290 (NF38_00290) - 60812..61342 (+) 531 WP_005688388.1 DsbE family thiol:disulfide interchange protein -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 25371.21 Da        Isoelectric Point: 9.5157

>NTDB_id=130675 NF38_RS00265 WP_011272301.1 55873..56556(-) (comP) [Haemophilus influenzae strain Hi375]
MTIQKGIITLTILIFISGLLSVILLLDDSNLSFFRAQQNQRKLYVERTLQLQRITALKKQTACLDLSLNNDESVKQISIT
LDGATDSIQYFLWCERMSLFKKSPKKGDNQGALKDFVSGEKLAYFRPHFSSPPRILNANKTPKLYWFSDSQAEVEINGTV
SAVLIAEGDLKLTGKGRISGAVITNGNLTLDGVTLAYGKKTVVALVQQYSQWKLAEKSWSDFNVQDE

Nucleotide


Download         Length: 684 bp        

>NTDB_id=130675 NF38_RS00265 WP_011272301.1 55873..56556(-) (comP) [Haemophilus influenzae strain Hi375]
ATGACAATACAAAAAGGTATTATTACGCTGACTATTCTGATTTTTATTTCAGGCTTATTAAGCGTAATCTTATTGTTAGA
TGATAGCAATTTAAGTTTTTTTCGGGCGCAACAAAATCAACGAAAACTGTATGTGGAAAGAACATTACAATTACAAAGAA
TAACAGCCTTGAAAAAACAAACTGCCTGCCTTGATTTATCATTAAATAATGATGAAAGTGTAAAGCAAATCAGCATTACG
CTTGATGGTGCCACAGATTCAATTCAATATTTTCTTTGGTGTGAAAGAATGAGCCTATTTAAAAAATCGCCTAAAAAGGG
AGATAATCAAGGCGCATTGAAAGATTTTGTGAGTGGCGAAAAACTTGCCTATTTTCGACCGCACTTTTCTTCTCCGCCCA
GAATTTTAAACGCGAATAAAACGCCTAAACTTTATTGGTTTTCAGATTCACAAGCAGAGGTTGAAATTAATGGCACGGTG
TCTGCCGTATTAATTGCAGAGGGCGATTTAAAATTGACTGGCAAAGGGAGGATTAGTGGCGCAGTGATTACCAACGGGAA
TTTAACTTTAGATGGCGTAACTTTAGCTTATGGGAAAAAGACGGTGGTCGCTTTAGTGCAACAATATAGTCAGTGGAAGT
TAGCAGAAAAAAGTTGGAGTGATTTTAATGTTCAGGATGAATAA

Domains

Predicted by InterproScan.

Protein of unknown function (DUF2572) (DUF2572)

(5-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Haemophilus influenzae Rd KW20

91.63

100

0.916

Multiple sequence alignment