Detailed information NTG0130607

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: BF33_RS01390
• Genome accession: NZ_CP009605
• Coordinates: 161110..161904 (+)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus cereus strain S2-8
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 156110..166904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BF33_RS01370 (BF33_190)	argR	156949..157398 (+)	450	WP_001032581.1	arginine repressor ArgR	-
BF33_RS01375 (BF33_191)	recN	157666..159405 (+)	1740	WP_000947757.1	DNA repair protein RecN	Machinery gene
BF33_RS01380 (BF33_192)	spoIVB	159524..160822 (+)	1299	WP_002037056.1	SpoIVB peptidase	-
BF33_RS01390 (BF33_193)	spo0A	161110..161904 (+)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
BF33_RS01395 (BF33_194)	-	162202..163728 (+)	1527	WP_000218391.1	glycosyltransferase family 39 protein	-
BF33_RS01400 (BF33_195)	-	163896..164042 (-)	147	WP_001247671.1	YycC family protein	-
BF33_RS01405 (BF33_196)	-	164093..164821 (+)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
BF33_RS01410 (BF33_197)	-	164870..165103 (-)	234	WP_001190185.1	DUF2627 domain-containing protein	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=130607 BF33_RS01390 WP_003161566.1 161110..161904(+) (spo0A) [Bacillus cereus strain S2-8]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=130607 BF33_RS01390 WP_003161566.1 161110..161904(+) (spo0A) [Bacillus cereus strain S2-8]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818