Detailed information NTG0130360

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: SAHC1335_RS04170
• Genome accession: NZ_CP012012
• Coordinates: 856463..857545 (+)
• Length: 360 a.a.
• NCBI ID: WP_001548033.1
• Uniprot ID: A0A0H2XJ41
• Organism: Staphylococcus aureus strain HC1335
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 851463..862545

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAHC1335_RS04150 (SAHC1335_03427)	gdpS	851835..852905 (-)	1071	WP_000460983.1	GGDEF domain-containing protein GdpS	-
SAHC1335_RS04155 (SAHC1335_01635)	-	853223..854278 (+)	1056	WP_000258151.1	glycosyltransferase family 4 protein	-
SAHC1335_RS04160 (SAHC1335_01636)	-	854448..855089 (-)	642	WP_000192947.1	YigZ family protein	-
SAHC1335_RS04165 (SAHC1335_01637)	fakB1	855233..856099 (+)	867	WP_000686342.1	fatty acid kinase binding subunit FakB1	-
SAHC1335_RS04170 (SAHC1335_01639)	comFA	856463..857545 (+)	1083	WP_001548033.1	DEAD/DEAH box helicase	Machinery gene
SAHC1335_RS04175 (SAHC1335_03429)	-	857538..858212 (+)	675	WP_059287708.1	ComF family protein	-
SAHC1335_RS04180 (SAHC1335_01642)	hpf	858273..858845 (+)	573	WP_000617735.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
SAHC1335_RS04185 (SAHC1335_01643)	secA	859259..861790 (+)	2532	WP_000506531.1	preprotein translocase subunit SecA	-
SAHC1335_RS04190	-	861832..861936 (+)	105	WP_001790092.1	hypothetical protein	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 42111.65 Da
• Isoelectric Point: 9.8307

>NTDB_id=130360 SAHC1335_RS04170 WP_001548033.1 856463..857545(+) (comFA) [Staphylococcus aureus strain HC1335]
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVS
PRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETM
IKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKL
ECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE

Nucleotide

• Length: 1083 bp

>NTDB_id=130360 SAHC1335_RS04170 WP_001548033.1 856463..857545(+) (comFA) [Staphylococcus aureus strain HC1335]
ATGGATAATGTAACAAGATATAAAATAACAGAGAGTTCGCAAAGTTCATCACAAGCATATTATCATCTCTCATTTGAATT
GTCGGAACAGCAGTCTTATGCCTCAGAACATATTGTTCGAGCCATTAGAAAGAGACAAACGATTTTGTTATATGCCGTAA
CAGGTGCAGGTAAGACAGAAATGATGTTTCAAGGCATTCAATATGCAAGAATACAGGGAGATAATATAGCTATTGTGTCA
CCACGTGTAGATGTTGTTGTAGAAATTAGTAAACGTATTAAAGACGCATTTCTTAATGAAGATATAGACATACTACACCA
GCAATCAAGACAACAATTTGAAGGGCATTTTGTTGTATGCACAGTGCATCAACTTTACCGATTCAAACAGCACTTTGATA
CTATTTTTATTGATGAAGTCGATGCCTTTCCTTTATCAATGGATAAAAATTTACAACAAGCATTGAAGTCATCTTCTAAA
GTTGAACATGCAACAATTTATATGACAGCAACACCACCGAAACAACTTCTGTCAGAGATTCCCCACGAAAATATAATTAA
ATTGCCAGCTCGCTTTCATAAAAAATCACTTCCAGTTCCTAAATATCGTTATTTCAAACTTAATAATAAGAAGATTCAGA
AAATGTTATACCGAATTTTACAAGATCAAATTAATAATCAACGTTATACACTGGTGTTTTTTAACAATATAGAAACAATG
ATTAAAACATTTTCGGTTTATAAGCAGAAAATTACTAAATTAACATACGTCCATAGCGAGGATGTTTTTCGCTTTGAAAA
AGTTGAACAATTAAGGAATGGACATTTCGATGTCATTTTTACTACGACAATATTAGAACGTGGATTTACAATGGCAAATT
TGGATGTTGTTGTTATCGATGCACATCAATATACTCAAGAGGCTTTAATACAAATTGCTGGACGTGTTGGACGAAAATTA
GAATGTCCTACTGGAAAAGTATTGTTTTTTCATGAAGGGGTAAGTATGAATATGATTCAAGCTAAAAAAGAGATTCAAAG
GATGAACAAATTAGCATTAAAAAGAGGTTGGATTGATGAATAA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (215-318)

• Type III restriction enzyme, res subunit (ResIII) (25-173)

3D structure

• AlphaFold DB: A0A0H2XJ41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Bacillus subtilis subsp. subtilis str. 168	38.938	94.167	0.367