Detailed information NTG0130272

Bioinformatically predicted

Overview

• Name: comFA
• Type: Machinery gene
• Locus tag: SAHC1340_RS04520
• Genome accession: NZ_CP012011
• Coordinates: 901623..902705 (+)
• Length: 360 a.a.
• NCBI ID: WP_001548033.1
• Uniprot ID: A0A0H2XJ41
• Organism: Staphylococcus aureus strain HC1340
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 896623..907705

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAHC1340_RS04500 (SAHC1340_01549)	gdpS	896995..898065 (-)	1071	WP_000460983.1	GGDEF domain-containing protein GdpS	-
SAHC1340_RS04505 (SAHC1340_01550)	-	898383..899438 (+)	1056	WP_000258151.1	glycosyltransferase family 4 protein	-
SAHC1340_RS04510 (SAHC1340_01551)	-	899608..900249 (-)	642	WP_000192947.1	YigZ family protein	-
SAHC1340_RS04515 (SAHC1340_01552)	fakB1	900393..901259 (+)	867	WP_000686342.1	fatty acid kinase binding subunit FakB1	-
SAHC1340_RS04520 (SAHC1340_01554)	comFA	901623..902705 (+)	1083	WP_001548033.1	DEAD/DEAH box helicase	Machinery gene
SAHC1340_RS04525 (SAHC1340_01556)	-	902698..903372 (+)	675	WP_001057965.1	ComF family protein	-
SAHC1340_RS04530 (SAHC1340_01557)	hpf	903433..904005 (+)	573	WP_000617735.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
SAHC1340_RS04535 (SAHC1340_01558)	secA	904419..906950 (+)	2532	WP_000506531.1	preprotein translocase subunit SecA	-
SAHC1340_RS04540	-	906992..907096 (+)	105	WP_001790092.1	hypothetical protein	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 42111.65 Da
• Isoelectric Point: 9.8307

>NTDB_id=130272 SAHC1340_RS04520 WP_001548033.1 901623..902705(+) (comFA) [Staphylococcus aureus strain HC1340]
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVS
PRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSK
VEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETM
IKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKL
ECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE

Nucleotide

• Length: 1083 bp

>NTDB_id=130272 SAHC1340_RS04520 WP_001548033.1 901623..902705(+) (comFA) [Staphylococcus aureus strain HC1340]
ATGGATAATGTAACAAGATATAAAATAACAGAGAGTTCGCAAAGTTCATCACAAGCATATTATCATCTCTCATTTGAATT
GTCGGAACAGCAGTCTTATGCCTCAGAACATATTGTTCGAGCCATTAGAAAGAGACAAACGATTTTGTTATATGCCGTAA
CAGGTGCAGGTAAGACAGAAATGATGTTTCAAGGCATTCAATATGCAAGAATACAGGGAGATAATATAGCTATTGTGTCA
CCACGTGTAGATGTTGTTGTAGAAATTAGTAAACGTATTAAAGACGCATTTCTTAATGAAGATATAGACATACTACACCA
GCAATCAAGACAACAATTTGAAGGGCATTTTGTTGTATGCACAGTGCATCAACTTTACCGATTCAAACAGCACTTTGATA
CTATTTTTATTGATGAAGTCGATGCCTTTCCTTTATCAATGGATAAAAATTTACAACAAGCATTGAAGTCATCTTCTAAA
GTTGAACATGCAACAATTTATATGACAGCAACACCACCGAAACAACTTCTGTCAGAGATTCCCCACGAAAATATAATTAA
ATTGCCAGCTCGCTTTCATAAAAAATCACTTCCAGTTCCTAAATATCGTTATTTCAAACTTAATAATAAGAAGATTCAGA
AAATGTTATACCGAATTTTACAAGATCAAATTAATAATCAACGTTATACACTGGTGTTTTTTAACAATATAGAAACAATG
ATTAAAACATTTTCGGTTTATAAGCAGAAAATTACTAAATTAACATACGTCCATAGCGAGGATGTTTTTCGCTTTGAAAA
AGTTGAACAATTAAGGAATGGACATTTCGATGTCATTTTTACTACGACAATATTAGAACGTGGATTTACAATGGCAAATT
TGGATGTTGTTGTTATCGATGCACATCAATATACTCAAGAGGCTTTAATACAAATTGCTGGACGTGTTGGACGAAAATTA
GAATGTCCTACTGGAAAAGTATTGTTTTTTCATGAAGGGGTAAGTATGAATATGATTCAAGCTAAAAAAGAGATTCAAAG
GATGAACAAATTAGCATTAAAAAGAGGTTGGATTGATGAATAA

Domains

Predicted by InterProScan.

• Helicase conserved C-terminal domain (Helicase_C) (215-318)

• Type III restriction enzyme, res subunit (ResIII) (25-173)

3D structure

• AlphaFold DB: A0A0H2XJ41

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFA	Bacillus subtilis subsp. subtilis str. 168	38.938	94.167	0.367