Detailed information NTG0130073

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: PA50071_RS23630
• Genome accession: NZ_CP012001
• Coordinates: 5125922..5128486 (-)
• Length: 854 a.a.
• NCBI ID: WP_003094682.1
• Uniprot ID: A0A0H2ZHB4
• Organism: Pseudomonas aeruginosa DSM 50071 = NBRC 12689 strain DSM 50071
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 5120922..5133486

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PA50071_RS23630 (PA50071_23640)	clpC	5125922..5128486 (-)	2565	WP_003094682.1	ATP-dependent chaperone ClpB	Regulator
PA50071_RS23635 (PA50071_23645)	pgeF	5128642..5129370 (-)	729	WP_012614543.1	peptidoglycan editing factor PgeF	-
PA50071_RS23640 (PA50071_23650)	rluD	5129367..5130329 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
PA50071_RS23645 (PA50071_23655)	-	5130475..5131500 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
PA50071_RS23650 (PA50071_23660)	-	5131657..5131902 (+)	246	WP_003102591.1	PP0621 family protein	-
PA50071_RS23655 (PA50071_23665)	pilS	5131892..5133484 (+)	1593	WP_003110428.1	two-component system sensor histidine kinase PilS	Regulator

Sequence

Protein

• Length: 854 a.a.
• Molecular weight: 95005.65 Da
• Isoelectric Point: 5.1331

>NTDB_id=130073 PA50071_RS23630 WP_003094682.1 5125922..5128486(-) (clpC) [Pseudomonas aeruginosa DSM 50071 = NBRC 12689 strain DSM 50071]
MRIDRLTSKLQLALSDAQSLAVGHDHPAIEPVHLLSALLEQQGGSIKPLLMQVGFDIAALRSGLNKELDALPKIQSPTGD
VNLSQDLARLLNQADRLAQQKGDQFISSELVLLAAMDENTRLGKLLLGQGVSRKALENAVANLRGGEAVNDPNVEESRQA
LDKYTVDMTKRAEEGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPDGLKDKRLLAL
DMGALIAGAKFRGEFEERLKAVLNELGKQEGRVILFIDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPSEEDTIAILRGLKERYEVHHGVSITDGAIIAAAKLSHRYITDRQLPDKAIDLIDEAASR
IRMEIDSKPEELDRLDRRLIQLKIEREALKKEDDEATRKRLAKLEEDIVKLEREYADLEEIWKSEKAEVQGSAQIQQKIE
QAKQEMEAARRKGDLESMARIQYQTIPDLERSLQMVDQHGKTENQLLRNKVTDEEIAEVVSKWTGIPVSKMLEGEREKLL
RMEQELHRRVIGQDEAVVAVSNAVRRSRAGLADPNRPSGSFLFLGPTGVGKTELCKALAEFLFDTEEALVRIDMSEFMEK
HSVARLIGAPPGYVGFEEGGYLTEAIRRKPYSVVLLDEVEKAHPDVFNILLQVLEDGRLTDSHGRTVDFRNTVVVMTSNL
GSAQIQELAGDREAQRAAVMDAVNAHFRPEFINRIDEVVVFEPLAREQIAGIAEIQLGRLRKRLAERELSLELSQEALDK
LIAVGFDPVYGARPLKRAIQRWIENPLAQLILAGKFAPGASISAKVEGDEIVFA

Nucleotide

• Length: 2565 bp

>NTDB_id=130073 PA50071_RS23630 WP_003094682.1 5125922..5128486(-) (clpC) [Pseudomonas aeruginosa DSM 50071 = NBRC 12689 strain DSM 50071]
ATGCGAATAGACCGTTTGACCAGCAAGCTGCAACTGGCGCTCTCCGACGCCCAGTCCCTGGCCGTTGGCCATGACCATCC
GGCCATCGAGCCGGTGCACCTGCTTTCCGCCCTGCTCGAGCAGCAAGGCGGTTCGATCAAGCCCCTGCTGATGCAGGTCG
GCTTCGATATCGCCGCCCTGCGCAGCGGCCTCAACAAAGAACTCGACGCGCTGCCGAAGATCCAGAGCCCGACCGGCGAC
GTGAACCTGTCCCAGGATCTCGCACGCCTGCTCAACCAGGCTGACCGCCTGGCCCAGCAGAAGGGCGACCAGTTCATCTC
CAGCGAGCTGGTATTGCTGGCCGCGATGGACGAGAACACCAGGCTCGGCAAGCTGCTGCTCGGCCAGGGCGTGTCGCGCA
AGGCGCTGGAGAATGCCGTGGCCAACCTGCGTGGCGGCGAAGCGGTGAACGACCCGAACGTCGAGGAGTCGCGCCAGGCG
CTGGACAAGTACACCGTCGACATGACCAAGCGCGCCGAGGAAGGCAAGCTCGACCCGGTGATCGGTCGCGACGACGAGAT
CCGCCGGACCATCCAGGTCCTGCAGCGGCGGACCAAGAACAACCCGGTGCTGATCGGCGAACCCGGCGTCGGCAAGACCG
CCATCGTCGAGGGCCTGGCCCAGCGCATCATCAACGGCGAAGTGCCGGACGGCCTCAAGGACAAGCGCCTGCTGGCCCTG
GACATGGGGGCGCTGATCGCCGGTGCCAAGTTCCGCGGCGAGTTCGAGGAACGCCTGAAGGCAGTCCTCAACGAACTGGG
CAAGCAGGAAGGCCGGGTCATCCTGTTCATCGACGAACTGCACACCATGGTCGGTGCCGGCAAGGCGGAAGGTGCCATGG
ACGCCGGCAACATGCTCAAGCCGGCTCTGGCGCGCGGCGAGCTGCACTGCGTCGGTGCTACTACCCTCGACGAGTATCGC
CAGTACATCGAGAAGGATGCCGCGCTGGAGCGCCGCTTCCAGAAGGTGCTGGTGGACGAACCGAGCGAGGAAGACACCAT
CGCCATCCTCCGTGGTCTCAAGGAACGCTATGAAGTGCACCATGGGGTGAGCATCACTGACGGCGCGATCATCGCCGCGG
CCAAGCTGTCGCACCGCTACATCACCGATCGGCAACTGCCGGACAAGGCCATCGACCTGATCGACGAGGCCGCCAGCCGC
ATCCGCATGGAGATCGACTCCAAGCCGGAGGAACTGGATCGTCTCGACCGTCGCCTGATCCAGCTGAAGATCGAGCGCGA
GGCGCTGAAGAAGGAAGACGACGAAGCCACCAGGAAGCGCTTGGCCAAGCTGGAGGAGGATATCGTCAAGCTCGAGCGCG
AATACGCCGACCTCGAGGAGATCTGGAAGTCCGAGAAGGCCGAGGTGCAGGGCTCGGCGCAGATCCAGCAGAAGATCGAG
CAGGCCAAGCAGGAGATGGAGGCGGCGCGGCGCAAGGGCGACCTCGAGAGCATGGCGCGCATCCAGTACCAGACCATCCC
GGACCTGGAACGCAGCCTGCAGATGGTCGACCAGCACGGCAAGACCGAGAACCAGTTGCTGCGCAACAAGGTGACCGACG
AGGAAATCGCCGAAGTGGTTTCCAAGTGGACCGGTATCCCGGTGTCGAAGATGCTCGAGGGCGAGCGCGAGAAGCTGCTG
CGCATGGAGCAGGAGCTGCATCGGCGAGTGATCGGCCAGGACGAGGCGGTAGTCGCCGTGTCCAACGCCGTGCGCCGTTC
GCGCGCCGGCCTCGCCGATCCGAACCGGCCGAGCGGCTCGTTCCTCTTCCTCGGCCCGACCGGGGTGGGCAAGACCGAGT
TGTGCAAGGCGCTGGCCGAGTTCCTCTTCGATACCGAGGAGGCGCTGGTGCGGATCGATATGTCCGAGTTCATGGAGAAA
CACTCGGTGGCCCGCCTGATCGGCGCGCCTCCGGGCTACGTCGGCTTCGAGGAAGGCGGCTACCTGACCGAGGCGATCCG
CCGCAAGCCTTACTCGGTGGTGCTGCTGGACGAGGTGGAGAAGGCCCATCCGGATGTATTCAACATTCTCCTCCAGGTGC
TCGAGGACGGACGCCTGACCGACAGTCACGGGCGTACGGTGGACTTCCGCAACACCGTGGTGGTGATGACCTCCAACCTC
GGTTCGGCACAGATCCAGGAGCTGGCCGGCGACCGCGAGGCGCAACGTGCCGCAGTGATGGACGCGGTCAATGCGCACTT
CCGTCCGGAATTCATCAACCGGATCGACGAAGTGGTGGTATTCGAGCCGCTGGCTCGCGAGCAGATCGCCGGCATCGCCG
AGATCCAGCTCGGTCGCCTGCGCAAGCGCCTGGCCGAGCGCGAGCTGAGCCTGGAACTGAGCCAGGAGGCGCTGGACAAG
CTGATCGCCGTCGGCTTCGACCCGGTCTATGGCGCACGCCCGCTGAAGCGGGCCATCCAGCGCTGGATCGAGAACCCGCT
GGCGCAACTGATCCTGGCCGGCAAATTCGCGCCGGGTGCCAGTATCTCGGCGAAGGTGGAAGGCGACGAGATCGTCTTCG
CCTGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (764-842)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-758)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• ATPase family associated with various cellular activities (AAA) (AAA) (203-334)

3D structure

• AlphaFold DB: A0A0H2ZHB4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	48.391	100	0.493
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.417	100	0.436