Detailed information NTG0130073

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: BG01_RS06140
• Genome accession: NZ_CP009544
• Coordinates: 865104..865898 (+)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis strain BA1015
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 860104..870898

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BG01_RS06125 (BG01_958)	argR	860943..861392 (+)	450	WP_001032581.1	arginine repressor ArgR	-
BG01_RS06130 (BG01_959)	recN	861660..863399 (+)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
BG01_RS06135 (BG01_960)	spoIVB	863518..864816 (+)	1299	WP_002037056.1	SpoIVB peptidase	-
BG01_RS06140 (BG01_961)	spo0A	865104..865898 (+)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
BG01_RS06145 (BG01_962)	-	866196..867722 (+)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
BG01_RS06150 (BG01_963)	-	867890..868036 (-)	147	WP_001247671.1	YycC family protein	-
BG01_RS06155 (BG01_964)	-	868087..868815 (+)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
BG01_RS06160 (BG01_965)	-	868864..869097 (-)	234	WP_001190187.1	DUF2627 domain-containing protein	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=130073 BG01_RS06140 WP_003161566.1 865104..865898(+) (spo0A) [Bacillus anthracis strain BA1015]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=130073 BG01_RS06140 WP_003161566.1 865104..865898(+) (spo0A) [Bacillus anthracis strain BA1015]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818