Detailed information NTG0129669

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LG36_RS10980
• Genome accession: NZ_CP009472
• Coordinates: 2274864..2275892 (-)
• Length: 342 a.a.
• NCBI ID: WP_003132657.1
• Uniprot ID: S6FVM6
• Organism: Lactococcus lactis strain AI06
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2269864..2280892

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LG36_RS10955 (LG36_2090)	-	2270149..2270646 (-)	498	WP_038602414.1	nitroreductase family protein	-
LG36_RS10960 (LG36_2091)	-	2270633..2270842 (-)	210	WP_003132661.1	hypothetical protein	-
LG36_RS10965 (LG36_2092)	-	2270839..2271666 (-)	828	WP_026138971.1	radical SAM protein	-
LG36_RS10970 (LG36_2093)	-	2271659..2273782 (-)	2124	WP_038602417.1	MFS transporter	-
LG36_RS10975 (LG36_2094)	-	2273885..2274742 (-)	858	WP_038602420.1	transcriptional regulator	-
LG36_RS10980 (LG36_2095)	sepM	2274864..2275892 (-)	1029	WP_003132657.1	SepM family pheromone-processing serine protease	Regulator
LG36_RS10985 (LG36_2096)	coaD	2275879..2276376 (-)	498	WP_038602423.1	pantetheine-phosphate adenylyltransferase	-
LG36_RS10990 (LG36_2097)	rsmD	2276424..2276963 (-)	540	WP_052053878.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LG36_RS10995 (LG36_2099)	-	2277132..2278352 (-)	1221	WP_038602963.1	MFS transporter	-
LG36_RS11000 (LG36_2100)	lmrP	2278435..2279661 (-)	1227	WP_038602426.1	multidrug efflux MFS transporter LmrP	-
LG36_RS11005 (LG36_2101)	-	2279849..2280343 (+)	495	WP_038602428.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37349.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=129669 LG36_RS10980 WP_003132657.1 2274864..2275892(-) (sepM) [Lactococcus lactis strain AI06]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=129669 LG36_RS10980 WP_003132657.1 2274864..2275892(-) (sepM) [Lactococcus lactis strain AI06]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTTCTGACGACTGTCCAAATTGCGCGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCGGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCCGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

3D structure

• AlphaFold DB: S6FVM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491