Detailed information NTG0129635

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LG36_RS03270
• Genome accession: NZ_CP009472
• Coordinates: 634129..636579 (+)
• Length: 816 a.a.
• NCBI ID: WP_038599607.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain AI06
• Function: degradation of ComX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	637456..646643	634129..636579	flank	877

Gene organization within MGE regions

Location: 634129..646643

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LG36_RS03270 (LG36_0602)	clpC	634129..636579 (+)	2451	WP_038599607.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
LG36_RS03275 (LG36_0603)	hpf	636714..637271 (+)	558	WP_003129564.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
LG36_RS03280 (LG36_0604)	eno	637456..638757 (+)	1302	WP_010905473.1	surface-displayed alpha-enolase	-
LG36_RS03285 (LG36_0605)	-	638872..639543 (-)	672	WP_038599611.1	ABC transporter ATP-binding protein	-
LG36_RS03290 (LG36_0606)	-	639546..640619 (-)	1074	WP_038599614.1	ABC transporter permease	-
LG36_RS03295 (LG36_0607)	-	640631..641200 (-)	570	WP_038599617.1	TetR/AcrR family transcriptional regulator	-
LG36_RS03300 (LG36_0608)	-	641387..642910 (-)	1524	WP_038599620.1	class I adenylate-forming enzyme family protein	-
LG36_RS03305 (LG36_0609)	-	643102..644019 (+)	918	WP_029344951.1	magnesium transporter CorA family protein	-
LG36_RS03310 (LG36_0610)	pflB	644280..646643 (+)	2364	WP_038599623.1	formate C-acetyltransferase	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90464.91 Da
• Isoelectric Point: 6.6286

>NTDB_id=129635 LG36_RS03270 WP_038599607.1 634129..636579(+) (clpC) [Lactococcus lactis strain AI06]
MKFENIKYTPTLDRILEKAEEYAHQYQYGTIESAHLLAAMATTSGSIAYSLLAGMNVDSSDLLIDLEDLSSHVKVKRSTL
RFSPRAEEVMTAASFLAIHNNSEAVGTEHLLYALLQVEDGFGLQLLKLQKINIVSLRKELEKRTGLKVPESKKAVTPMSK
RKMAKGVAENSTTPTLDSVSSDLTEEARLGKLDPMIGREAEIDRLIHILSRRTKNNPVLVGEPGVGKSAIIEGLAQRIVN
GQVPIGLMNSRIMALNMATVVAGTKFRGEFEDRLTAIVEEVSSDPDVIIFIDELHTIIGAGGGMDSVNDAANILKPALAR
GDFQMVGATTYHEYQKYIEKDEALERRLARINVDEPSPDEAIAILRGLREKFEDYHQVKFTDQAIKSAVMLSVRYMTSRK
LPDKAIDLLDEAAAAVKISVKNQQAKRLDLEKELAEAQEELSEAVIKLDIKASRTKEKAVEKIADKIYKFSVKEDKRQEV
TDQAVVAVASTLTGVPITQMTKSESDRLINLEKELHKRVVGQEEAISAVSRAIRRARSGVADSRRPMGSFMFLGPTGVGK
TELAKALADSVFGNEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSVVLLDEVEKAHPDVFNIML
QILDDGFVTDTKGRKVDFRNTIIIMTSNLGATALRDDKTVGFGAKNITADYSAMKSRILEELKRHYRPEFLNRIDENIVF
HSLESQEIEQIVKIMSKSLIKRLAEQDIHVKLTPSAVKLIAEIGFDPEYGARPLRKALQKEVEDLLSEQLLSGEIKAGNH
VSIGASNKKIKIAQIV

Nucleotide

• Length: 2451 bp

>NTDB_id=129635 LG36_RS03270 WP_038599607.1 634129..636579(+) (clpC) [Lactococcus lactis strain AI06]
ATGAAATTTGAAAATATAAAATATACACCAACGCTTGACCGAATTTTAGAAAAAGCGGAAGAGTACGCTCACCAATATCA
ATATGGCACCATTGAAAGTGCACATTTACTGGCTGCAATGGCAACGACCTCAGGCTCAATTGCTTACAGCCTTCTTGCAG
GAATGAATGTTGATTCTTCTGACTTACTGATTGATTTAGAGGATTTATCAAGTCATGTTAAGGTCAAACGTTCAACTTTA
CGTTTTTCACCTCGTGCAGAGGAAGTGATGACTGCGGCAAGTTTTTTAGCAATTCATAATAACTCCGAAGCCGTTGGAAC
AGAACACCTGCTTTATGCCCTACTTCAAGTAGAAGATGGATTTGGTCTTCAACTTCTAAAATTACAAAAAATCAATATTG
TATCTTTGCGAAAAGAGCTTGAGAAAAGAACTGGACTCAAAGTTCCAGAAAGTAAAAAAGCTGTGACTCCAATGTCAAAA
CGCAAGATGGCAAAGGGAGTTGCAGAAAATTCAACGACGCCAACGTTAGACTCTGTATCCTCAGATTTAACCGAAGAAGC
TCGTTTGGGTAAACTTGACCCAATGATTGGACGAGAAGCTGAAATTGACCGTTTGATTCATATTCTCAGCCGCAGAACAA
AAAATAATCCTGTCTTAGTTGGAGAGCCCGGTGTTGGGAAATCAGCAATTATTGAAGGTTTGGCCCAAAGAATTGTCAAT
GGTCAAGTTCCAATTGGTTTGATGAATAGTCGAATTATGGCATTGAATATGGCGACTGTTGTTGCTGGGACAAAATTTAG
AGGTGAATTTGAGGATCGTTTGACAGCTATTGTTGAAGAAGTTAGCAGTGATCCAGATGTCATTATTTTCATTGATGAAT
TACACACAATCATTGGTGCTGGTGGCGGTATGGATTCTGTCAATGATGCCGCAAATATTTTGAAACCAGCGCTTGCTCGT
GGTGATTTTCAAATGGTCGGAGCAACAACCTATCATGAATATCAAAAATATATTGAAAAGGATGAAGCTTTAGAACGCCG
TTTGGCGAGAATAAATGTTGATGAGCCAAGTCCAGATGAAGCGATTGCTATTTTGCGAGGCTTACGTGAAAAATTTGAAG
ACTATCATCAAGTGAAATTTACTGACCAAGCCATTAAAAGTGCTGTAATGCTCAGTGTTCGTTATATGACCAGCAGAAAA
TTGCCTGACAAAGCCATTGATTTACTTGATGAAGCTGCAGCAGCGGTGAAAATTTCTGTCAAAAATCAACAAGCAAAACG
TCTTGATTTAGAAAAAGAACTAGCCGAAGCTCAAGAAGAATTATCAGAAGCTGTCATTAAGCTTGACATCAAAGCGTCTC
GTACAAAAGAAAAAGCAGTTGAAAAAATTGCTGACAAGATTTATAAATTCTCAGTAAAAGAAGATAAACGTCAAGAAGTT
ACTGACCAAGCTGTTGTTGCTGTTGCCTCAACACTGACAGGTGTTCCAATCACACAAATGACTAAGTCTGAAAGTGATCG
TTTAATCAATCTTGAAAAAGAATTACACAAACGAGTTGTTGGACAAGAAGAAGCTATTTCTGCCGTTTCAAGAGCCATTC
GTCGGGCACGTTCTGGTGTTGCTGACAGTCGCCGTCCAATGGGTTCTTTCATGTTCCTTGGACCAACAGGGGTCGGTAAA
ACCGAACTTGCTAAAGCACTGGCTGACAGTGTGTTTGGTAATGAAGATAATATGATTCGTGTTGACATGAGTGAATTCAT
GGAAAAACATTCGACTTCACGCTTGATTGGAGCTCCTCCAGGGTATGTAGGTTATGATGAGGGTGGTCAATTGACAGAAC
GCGTTCGTAATAAACCTTATTCAGTTGTTCTTTTAGATGAAGTCGAAAAAGCTCATCCTGACGTTTTCAACATCATGTTG
CAAATTCTAGATGATGGCTTTGTGACTGATACTAAAGGTCGCAAAGTTGATTTCAGAAATACAATTATTATCATGACTTC
AAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACAGTTGGTTTTGGCGCTAAAAATATCACAGCTGATTATTCAGCCA
TGAAATCAAGAATATTAGAAGAGCTTAAACGTCATTATCGTCCTGAGTTTCTTAATCGAATTGATGAAAATATTGTTTTC
CATTCATTGGAAAGTCAAGAGATTGAACAAATTGTTAAAATTATGAGTAAATCTTTGATTAAACGTCTGGCAGAACAAGA
TATTCATGTTAAACTCACACCATCAGCGGTGAAATTAATTGCTGAAATAGGTTTTGACCCAGAATATGGTGCACGTCCTC
TACGTAAGGCACTTCAAAAAGAAGTCGAAGACCTTTTAAGTGAACAACTGCTCTCTGGTGAAATCAAAGCAGGTAATCAT
GTTTCAATTGGTGCATCTAATAAAAAAATTAAAATCGCTCAAATTGTTTGA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-802)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-69)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-144)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-334)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• AAA lid domain (AAA_lid_9) (357-453)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	99.51	100	0.995
clpC	Streptococcus thermophilus LMG 18311	50.903	100	0.518
clpC	Streptococcus thermophilus LMD-9	50.542	100	0.515
clpC	Streptococcus pneumoniae Rx1	48.798	100	0.498
clpC	Streptococcus pneumoniae D39	48.798	100	0.498
clpC	Streptococcus pneumoniae TIGR4	48.678	100	0.496
clpC	Streptococcus mutans UA159	48.558	100	0.495
clpC	Bacillus subtilis subsp. subtilis str. 168	50.374	98.284	0.495
clpE	Streptococcus mutans UA159	47.692	79.657	0.38
clpC	Lactococcus lactis subsp. cremoris KW2	47.023	80.27	0.377
clpE	Streptococcus pneumoniae TIGR4	47.528	76.838	0.365
clpE	Streptococcus pneumoniae Rx1	47.528	76.838	0.365
clpE	Streptococcus pneumoniae D39	47.528	76.838	0.365
clpE	Streptococcus pneumoniae R6	47.528	76.838	0.365