Detailed information NTG0129197

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: LG33_RS10800
• Genome accession: NZ_CP009423
• Coordinates: 2058595..2059638 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain USA300_SUR1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2053595..2064638

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LG33_RS10770 (LG33_10625)	-	2054013..2055269 (-)	1257	WP_001795438.1	aminopeptidase	-
LG33_RS10775 (LG33_10630)	-	2055272..2055472 (-)	201	WP_000180461.1	DUF1128 family protein	-
LG33_RS10780 (LG33_10635)	-	2055619..2056083 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
LG33_RS10785 (LG33_10640)	-	2056090..2056365 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
LG33_RS10790 (LG33_10645)	-	2056643..2057860 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
LG33_RS10795 (LG33_10650)	vraR	2057976..2058605 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
LG33_RS10800 (LG33_10655)	vraS	2058595..2059638 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
LG33_RS10805 (LG33_10660)	liaF	2059635..2060336 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
LG33_RS10810 (LG33_10665)	-	2060351..2060737 (-)	387	WP_001110179.1	hypothetical protein	-
LG33_RS10815 (LG33_10670)	map	2060954..2061712 (-)	759	WP_050901419.1	type I methionyl aminopeptidase	-
LG33_RS10820 (LG33_10680)	-	2062240..2063226 (+)	987	WP_000999713.1	FUSC family protein	-
LG33_RS10830 (LG33_10685)	-	2063716..2064129 (-)	414	WP_001549145.1	hypothetical protein	-
LG33_RS10835 (LG33_10690)	-	2064158..2064268 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=129197 LG33_RS10800 WP_001017131.1 2058595..2059638(-) (vraS) [Staphylococcus aureus strain USA300_SUR1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=129197 LG33_RS10800 WP_001017131.1 2058595..2059638(-) (vraS) [Staphylococcus aureus strain USA300_SUR1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1