Detailed information NTG0129167

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: M444_RS18795
• Genome accession: NZ_CP011664
• Coordinates: 4364964..4367549 (+)
• Length: 861 a.a.
• NCBI ID: WP_008741407.1
• Uniprot ID: -
• Organism: Streptomyces sp. Mg1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 4359964..4372549

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M444_RS18765 (M444_18745)	grpE	4360054..4360740 (+)	687	WP_008741413.1	nucleotide exchange factor GrpE	-
M444_RS18770 (M444_18750)	dnaJ	4360780..4361970 (+)	1191	WP_008741412.1	molecular chaperone DnaJ	-
M444_RS18775 (M444_18755)	-	4361972..4362436 (+)	465	WP_008741411.1	helix-turn-helix domain-containing protein	-
M444_RS18780 (M444_18760)	-	4362542..4363570 (-)	1029	WP_008741410.1	regulatory protein	-
M444_RS41070	-	4363673..4363930 (+)	258	WP_162493666.1	hypothetical protein	-
M444_RS18785 (M444_18765)	-	4363930..4364244 (+)	315	WP_037793158.1	(2Fe-2S)-binding protein	-
M444_RS18790 (M444_18770)	-	4364406..4364837 (-)	432	WP_037793156.1	pyridoxamine 5'-phosphate oxidase family protein	-
M444_RS18795 (M444_18775)	clpC	4364964..4367549 (+)	2586	WP_008741407.1	ATP-dependent chaperone ClpB	Regulator
M444_RS18800 (M444_18780)	-	4367692..4368939 (+)	1248	WP_158512308.1	ATP-binding protein	-
M444_RS18805 (M444_18785)	-	4368914..4369513 (+)	600	WP_008741404.1	RloB family protein	-
M444_RS18810 (M444_18790)	-	4369614..4370165 (+)	552	WP_008741403.1	YbjN domain-containing protein	-
M444_RS18815 (M444_18795)	-	4370176..4371303 (-)	1128	WP_047960637.1	glycosyltransferase family 39 protein	-
M444_RS18820 (M444_18800)	-	4371300..4372487 (-)	1188	WP_008741401.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 861 a.a.
• Molecular weight: 93477.89 Da
• Isoelectric Point: 4.7067

>NTDB_id=129167 M444_RS18795 WP_008741407.1 4364964..4367549(+) (clpC) [Streptomyces sp. Mg1]
MDAELTNKSRDALNAATSRAVKDGNADLTPAHLLLALLAGQDNENITDLLAATEADQAAVRDGAERLVAALPSVTGSTVA
PPQATRDLLAVLAEADAQAGKLGDEYLSTEHLLIALAAKGAAAGEVLSAEGATAAKLLAAFQNARGGRRVTSPDPEGQYK
ALEKFGTDFTAAAREGKLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLKNKRLVS
LDLGAMVAGAKYRGEFEERLKTVLAEIKSSDGQIITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELRMVGATTLDE
YRERIEKDPALERRFQQVLVAEPSVEDTIAILRGLKGRYEAHHKVVINDSALVAAATLSDRYITSRFLPDKAIDLVDEAA
SRLRMEIDSSPLEIDELQRAVDRLRMEELALKNESDPASLERLDKLRKDLADKEEDLRGLTARWEKEKQSLNRVGELKER
LDDLRGQAERAQRDGDFDAASKLLYGEIPELERELEEATEAEAEASKGTMVKDEVGPDDIADVVGAWTGIPAGRLLEGET
QKLLRMEDELGRRLIGQQEAVRAVSDAVRRTRAGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRIDMSE
YSEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVVLLDEVEKAHPEVFDILLQVLDDGRLTDGQGRTVDFRNTILIL
TSNLGSQFLMDPATSDQDKKARVLEVVRASFKPEFLNRLDDLVVFSALTRDELAHIAELQIGSLARRLAARRLTLDVTPD
ALAWLADKGNDPAYGARPLRRLIQTAIGDRLAKEILSGEVKDGDTVRVAVAGEDLLVGKAL

Nucleotide

• Length: 2586 bp

>NTDB_id=129167 M444_RS18795 WP_008741407.1 4364964..4367549(+) (clpC) [Streptomyces sp. Mg1]
GTGGATGCCGAGCTGACCAACAAGAGCCGGGACGCGCTCAACGCGGCCACCAGCAGGGCCGTCAAGGACGGGAACGCGGA
CCTGACCCCCGCACACCTGCTCCTGGCCCTGCTCGCCGGCCAGGACAACGAGAACATCACCGATCTGCTCGCCGCCACCG
AGGCCGACCAGGCCGCCGTGCGCGACGGCGCGGAGCGGCTCGTCGCCGCCCTGCCCAGCGTCACCGGCTCCACCGTCGCG
CCCCCGCAGGCGACCCGCGACCTCCTCGCCGTACTCGCCGAGGCCGACGCGCAGGCCGGGAAGCTCGGCGACGAGTACCT
GTCCACCGAACACCTCCTCATCGCCCTCGCCGCCAAGGGCGCGGCGGCCGGTGAGGTCCTTTCCGCCGAGGGCGCGACCG
CCGCGAAGCTGCTGGCCGCCTTCCAGAACGCACGAGGAGGCCGGCGGGTGACCAGCCCCGACCCCGAGGGCCAGTACAAG
GCCCTGGAGAAGTTCGGCACGGACTTCACGGCCGCCGCCCGCGAGGGCAAGCTCGACCCGGTCATCGGCCGCGACCAGGA
GATCCGGCGCGTCGTCCAGGTCCTCTCCCGGCGTACGAAGAACAACCCGGTGCTCATCGGCGAGCCCGGCGTCGGCAAGA
CGGCCGTCGTCGAGGGCCTGGCCCAGCGCATCGTCAAGGGCGACGTCCCCGAGTCCCTGAAGAACAAGCGGCTGGTCTCC
CTCGACCTCGGCGCGATGGTCGCGGGCGCCAAGTACCGCGGCGAGTTCGAGGAGCGCCTGAAGACCGTCCTCGCCGAGAT
CAAGTCGAGCGACGGCCAGATCATCACCTTCATCGACGAGCTCCACACCGTCGTCGGCGCGGGCGCCGGCGGGGACTCCG
CCATGGACGCGGGCAACATGCTCAAGCCCATGCTGGCCCGAGGCGAGCTGCGGATGGTCGGCGCGACCACCCTCGACGAG
TACCGCGAGCGCATCGAGAAGGACCCCGCGCTGGAGCGCCGCTTCCAGCAGGTGCTGGTGGCGGAGCCGAGCGTCGAGGA
CACCATCGCGATCCTGCGCGGCCTCAAGGGCCGGTACGAGGCGCACCACAAGGTCGTCATCAACGACAGCGCGCTCGTCG
CCGCGGCCACCCTCTCCGACCGGTACATCACCTCCCGGTTCCTCCCCGACAAGGCCATCGACCTCGTCGACGAGGCCGCG
TCCCGGCTGCGCATGGAGATCGACTCCTCCCCGCTGGAGATCGACGAGCTCCAGCGCGCCGTGGACCGCCTGCGCATGGA
GGAGCTGGCGCTGAAGAACGAGTCCGACCCGGCCTCGCTGGAGCGCCTCGACAAGCTGCGCAAGGACCTCGCGGACAAGG
AGGAGGACCTGCGCGGCCTGACCGCCCGCTGGGAGAAGGAGAAGCAGTCCCTCAACCGGGTCGGCGAGCTCAAGGAGCGC
CTCGACGACCTGCGCGGGCAGGCCGAGCGCGCCCAGCGCGACGGCGACTTCGACGCCGCCTCCAAGCTGCTCTACGGGGA
GATCCCCGAGCTGGAGCGCGAGCTGGAGGAGGCCACCGAGGCCGAGGCCGAGGCCTCCAAGGGGACGATGGTCAAGGACG
AGGTCGGCCCCGACGACATCGCGGACGTGGTGGGCGCCTGGACGGGCATCCCGGCGGGCCGCCTCCTGGAGGGCGAGACG
CAGAAGCTGCTGCGCATGGAGGACGAGCTGGGCCGCCGCCTGATCGGCCAGCAAGAGGCCGTACGGGCCGTCTCGGACGC
CGTGCGCCGCACCCGGGCCGGCATCGCCGACCCGGACCGCCCGACGGGCTCCTTCCTCTTCCTGGGGCCCACGGGCGTCG
GCAAGACGGAGCTGGCGAAGGCCCTCGCGGACTTCCTCTTCGACGACGAGCGGGCCATGGTCCGCATCGACATGTCGGAG
TACTCCGAGAAGCACAGCGTGGCCCGGCTGGTCGGCGCCCCGCCCGGGTACGTGGGCTACGAGGAGGGCGGCCAGCTCAC
CGAGGCCGTCCGGCGCCGCCCGTACAGCGTGGTGCTGCTGGACGAGGTGGAGAAGGCCCACCCCGAGGTCTTCGACATCC
TGCTCCAGGTCCTCGACGACGGCCGCCTCACGGACGGCCAGGGCCGCACCGTGGACTTCCGCAACACCATCCTGATCCTG
ACCTCCAACCTGGGCAGCCAGTTCCTGATGGACCCGGCCACCTCGGACCAGGACAAGAAGGCCAGGGTCCTGGAAGTGGT
CAGGGCCTCCTTCAAGCCCGAGTTCCTCAACCGCCTCGACGACCTCGTGGTCTTCTCCGCCCTGACCCGGGACGAGCTGG
CGCACATCGCCGAGCTCCAGATCGGCTCCCTCGCCAGGCGGCTGGCCGCCCGCCGCCTGACCCTGGACGTCACCCCCGAC
GCCCTGGCCTGGCTCGCGGACAAGGGCAACGACCCCGCCTACGGAGCCCGCCCGCTGCGCCGCCTGATCCAGACGGCGAT
CGGCGACCGCCTGGCCAAGGAGATCCTCTCCGGCGAGGTCAAGGACGGCGACACCGTCCGCGTCGCCGTGGCCGGCGAGG
ACCTCCTGGTCGGCAAGGCCCTCTGA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-67)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-146)

• AAA lid domain (AAA_lid_9) (344-446)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-761)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-338)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (768-848)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.704	100	0.463
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.893	82.23	0.386
clpC	Lactococcus lactis subsp. cremoris KW2	45.816	81.882	0.375
clpE	Streptococcus pneumoniae TIGR4	46.512	79.907	0.372
clpE	Streptococcus mutans UA159	47.478	78.281	0.372