Detailed information NTG0129137

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: M444_RS02060
• Genome accession: NZ_CP011664
• Coordinates: 436979..439618 (-)
• Length: 879 a.a.
• NCBI ID: WP_008734882.1
• Uniprot ID: -
• Organism: Streptomyces sp. Mg1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 431979..444618

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M444_RS02040 (M444_02030)	-	433204..434307 (-)	1104	WP_037789865.1	hypothetical protein	-
M444_RS02045 (M444_02035)	-	434439..436190 (-)	1752	WP_037789624.1	cyclic nucleotide-binding domain-containing thioredoxin-disulfide reductase	-
M444_RS02050 (M444_02040)	-	436190..436453 (-)	264	WP_008734877.1	UBP-type zinc finger domain-containing protein	-
M444_RS02055 (M444_02045)	trxA	436524..436982 (-)	459	WP_008734880.1	thioredoxin	-
M444_RS02060 (M444_02050)	clpC	436979..439618 (-)	2640	WP_008734882.1	ATP-dependent chaperone ClpB	Regulator
M444_RS02065 (M444_02055)	-	439609..440016 (-)	408	WP_008734883.1	chaperone modulator CbpM	-
M444_RS02070 (M444_02060)	-	440016..440963 (-)	948	WP_008734885.1	J domain-containing protein	-
M444_RS02075 (M444_02065)	grpE	440970..441578 (-)	609	WP_008734887.1	nucleotide exchange factor GrpE	-
M444_RS02080 (M444_02070)	dnaK	441587..443488 (-)	1902	WP_008734888.1	molecular chaperone DnaK	-

Sequence

Protein

• Length: 879 a.a.
• Molecular weight: 98458.61 Da
• Isoelectric Point: 5.1296

>NTDB_id=129137 M444_RS02060 WP_008734882.1 436979..439618(-) (clpC) [Streptomyces sp. Mg1]
MDMNRLTQKSQEALQEAQTAAGRMGHTEVDGEHLLLALLDQEDGLIPRLLEQAGKEPKGLREAVREELSRRPKVTGPGAA
PGQVFVTQRLAHLLDAAEREAKRLKDEYVSVEHLLLALAEESSSTAAGRLLKQAGITRDSFLSALTQVRGNQRVTSANPE
VAYEALEKYGRDLVLEARSGRLDPVIGRDAEIRRVTQILSRKTKNNPVLIGDPGVGKTAIVEGLAQRIVRGDVPEGLRDR
TVFALDMGSLVAGAKYRGEFEERLKAVLSEVKAAQGRILLFVDELHTVVGAGAAEGAMDAGNMLKPMLARGELHMVGATT
LDEYRKHIEKDAALERRFQQVLVEEPSVEDTISILRGLRERLEVFHGVKIQDTALVSAATLSHRYITDRFLPDKAIDLVD
EACARLRTEIDSMPAELDEITRRVTRLEIEDAALSKETDPASKTRLEELRRELADLRGEADAKHAQWEAERQAIRRVQEL
RQELEQVRHEAEEAERAYDLNRAAELRYGSLQDLERRLAAEEEQLAAKQGQNRLLREVVTEEEIAEIVAAWTGVPVARLQ
EGEREKLLRLDEILRERVIGQDEAVKLVTDAIIRARSGIRDPRRPIGSFIFLGPTGVGKTELAKTLARTLFDSEENMVRL
DMSEYQERHTVSRLMGAPPGYVGYEEGGQLTEAVRRKPYSVVLFDEIEKAHTDVFNTLLQILDDGRITDAQGRTVDFRNT
VIIMTSNIGSEHLLDGATAEGEIKPDARALVMGELRGHFRPEFLNRVDDIVLFKPLGERQIERIVELQFDELRRRLAERR
ITVELSDVARQVIAHQGYDPVYGARPLRRYISHEVETLVGRALLRGDVQDGATVRVDAEHGELVVTYDQQDRDLEARAA

Nucleotide

• Length: 2640 bp

>NTDB_id=129137 M444_RS02060 WP_008734882.1 436979..439618(-) (clpC) [Streptomyces sp. Mg1]
ATGGACATGAACCGTCTCACCCAGAAGTCCCAGGAAGCCCTCCAGGAGGCCCAGACCGCAGCCGGCCGCATGGGGCACAC
CGAGGTCGACGGTGAACACCTGCTGCTCGCACTTCTCGATCAGGAGGACGGCCTGATCCCGCGGTTGCTGGAGCAGGCCG
GCAAGGAGCCGAAGGGACTGCGCGAGGCCGTGCGCGAGGAACTCTCCCGCCGCCCGAAGGTCACCGGCCCAGGCGCGGCA
CCCGGCCAGGTCTTCGTCACCCAGCGCCTCGCCCACCTGCTTGACGCCGCCGAACGGGAGGCCAAACGCCTCAAGGACGA
GTACGTGTCCGTGGAGCACCTCCTGCTCGCCCTGGCGGAGGAGAGCTCTTCGACCGCCGCCGGGCGACTTCTCAAACAGG
CCGGCATCACCAGGGACTCGTTCCTGAGCGCGCTCACCCAGGTCCGCGGCAACCAGCGCGTCACGTCCGCCAACCCCGAA
GTGGCCTACGAGGCGCTGGAGAAGTACGGACGCGACCTCGTCCTCGAGGCTCGGTCCGGGCGGCTGGACCCGGTCATCGG
CCGTGACGCGGAGATCCGCCGTGTCACCCAGATCCTCAGCCGCAAGACCAAGAACAACCCCGTACTCATCGGCGACCCCG
GCGTCGGCAAGACCGCCATTGTCGAGGGCCTGGCCCAGCGCATCGTCCGCGGCGATGTCCCCGAGGGCCTGCGCGACAGG
ACGGTGTTCGCCCTCGACATGGGCTCCCTGGTCGCTGGCGCCAAGTACCGCGGCGAGTTCGAGGAACGCCTGAAGGCCGT
GCTGTCCGAAGTGAAGGCCGCCCAAGGGCGCATCCTGCTCTTCGTCGACGAACTCCACACCGTCGTCGGCGCAGGCGCCG
CCGAAGGAGCGATGGACGCAGGCAACATGCTCAAGCCGATGCTGGCCCGAGGCGAACTCCACATGGTCGGCGCCACCACC
CTCGACGAGTACCGCAAGCACATCGAGAAGGACGCCGCCCTCGAACGCCGCTTCCAGCAGGTCCTGGTCGAGGAGCCCAG
CGTGGAGGACACCATCTCCATCCTGCGCGGACTGCGCGAACGCCTTGAGGTCTTCCACGGCGTGAAGATCCAGGACACGG
CGCTGGTCTCCGCGGCCACCCTCAGCCACCGTTACATCACCGATCGGTTCCTGCCCGACAAGGCCATCGACCTCGTCGAC
GAGGCGTGCGCCAGGCTGCGTACCGAGATCGACTCGATGCCCGCCGAACTCGACGAGATCACCCGCCGCGTCACGCGGCT
GGAGATCGAGGATGCCGCCCTGTCCAAGGAGACCGATCCCGCCAGCAAGACACGCCTGGAGGAGCTGCGCAGGGAACTGG
CCGACCTGCGCGGCGAGGCCGACGCCAAACACGCCCAGTGGGAGGCCGAACGGCAGGCGATCCGCCGCGTGCAGGAACTG
CGCCAGGAACTGGAACAGGTCCGCCACGAGGCCGAGGAAGCCGAACGCGCCTACGACCTCAACCGCGCCGCCGAACTGCG
CTACGGCAGCCTCCAGGACCTGGAGCGCCGACTCGCCGCGGAGGAGGAGCAACTGGCCGCCAAACAAGGTCAGAACCGGC
TGCTGCGCGAGGTCGTCACCGAGGAGGAGATCGCCGAGATCGTCGCCGCCTGGACCGGCGTCCCCGTCGCTCGCCTCCAG
GAGGGCGAACGCGAGAAGCTGCTGCGCCTCGACGAGATCCTGCGCGAGCGCGTCATCGGCCAGGACGAGGCCGTCAAGCT
CGTCACCGACGCCATCATCCGTGCCCGCTCCGGCATCCGCGACCCTCGCCGCCCCATCGGCTCGTTCATCTTCCTCGGCC
CCACCGGCGTTGGGAAGACCGAGCTTGCCAAGACCCTCGCCCGGACTCTGTTCGACTCCGAGGAGAACATGGTCCGCCTC
GACATGAGCGAGTACCAGGAGCGGCACACCGTCAGCCGGCTCATGGGCGCGCCGCCCGGATACGTCGGCTACGAGGAGGG
CGGCCAGCTCACCGAGGCCGTACGCCGCAAGCCGTACTCGGTCGTCCTGTTCGACGAGATCGAGAAGGCGCACACCGATG
TCTTCAACACGCTGCTGCAGATCCTTGATGACGGTCGCATCACCGACGCCCAGGGCCGTACCGTCGACTTCCGCAACACC
GTGATCATCATGACGTCCAACATCGGCTCCGAGCACCTCCTCGACGGCGCCACCGCCGAGGGTGAGATCAAGCCCGACGC
CCGCGCCTTGGTGATGGGCGAGCTGCGCGGGCACTTCCGCCCGGAGTTCCTCAACCGCGTCGACGACATCGTGCTGTTCA
AGCCGCTCGGTGAGCGGCAGATCGAACGGATCGTGGAACTGCAGTTCGACGAGCTGCGGCGGCGGCTCGCCGAGCGCCGC
ATCACCGTCGAACTGTCGGACGTTGCACGGCAGGTGATCGCCCACCAGGGCTACGACCCGGTGTACGGGGCTCGGCCACT
GCGGCGTTACATCTCCCACGAGGTCGAGACGCTGGTCGGGCGGGCCCTGCTGCGCGGCGATGTCCAGGACGGTGCGACGG
TGCGCGTCGACGCCGAGCACGGAGAGCTGGTGGTCACCTACGACCAGCAGGACCGCGACCTGGAAGCGAGGGCGGCGTGA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (604-770)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (776-856)

• ATPase family associated with various cellular activities (AAA) (AAA) (208-340)

• AAA lid domain (AAA_lid_9) (347-449)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-150)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	45.506	100	0.455
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	40.571	99.545	0.404
clpC	Lactococcus lactis subsp. cremoris KW2	46.619	79.067	0.369