Detailed information NTG0129126

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: ABO05_RS08850
• Genome accession: NZ_CP011535
• Coordinates: 1809114..1809881 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain M28PF1
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1804114..1814881

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABO05_RS08840 (ABO05_08860)	hexB	1804632..1806614 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
ABO05_RS08845 (ABO05_08865)	-	1806709..1807860 (-)	1152	WP_003058754.1	site-specific integrase	-
ABO05_RS10320	-	1808109..1808252 (+)	144	WP_011185066.1	putative holin-like toxin	-
ABO05_RS08850 (ABO05_08870)	irvR	1809114..1809881 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
ABO05_RS08855 (ABO05_08875)	-	1810035..1810241 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
ABO05_RS08860 (ABO05_08880)	-	1810275..1810475 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
ABO05_RS08865 (ABO05_08885)	-	1810496..1810903 (+)	408	WP_002992501.1	hypothetical protein	-
ABO05_RS10325	-	1810916..1811038 (+)	123	WP_011285272.1	hypothetical protein	-
ABO05_RS08870 (ABO05_08890)	-	1811321..1811842 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
ABO05_RS08875 (ABO05_08895)	-	1812090..1812263 (+)	174	WP_000132665.1	hypothetical protein	-
ABO05_RS08880 (ABO05_08900)	-	1812481..1812654 (+)	174	WP_000074663.1	plasmid mobilization protein	-
ABO05_RS08885 (ABO05_08905)	-	1812816..1813247 (+)	432	WP_136302445.1	hypothetical protein	-
ABO05_RS08890 (ABO05_08910)	-	1813349..1813681 (+)	333	WP_011285276.1	hypothetical protein	-
ABO05_RS08895 (ABO05_08915)	-	1813681..1813872 (+)	192	WP_021340709.1	hypothetical protein	-
ABO05_RS08900 (ABO05_08920)	-	1813884..1814213 (+)	330	WP_003058810.1	hypothetical protein	-
ABO05_RS08905 (ABO05_08925)	-	1814216..1814488 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=129126 ABO05_RS08850 WP_003058809.1 1809114..1809881(-) (irvR) [Streptococcus pyogenes strain M28PF1]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=129126 ABO05_RS08850 WP_003058809.1 1809114..1809881(-) (irvR) [Streptococcus pyogenes strain M28PF1]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4