Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   LA24_RS04955 Genome accession   NZ_CP009419
Coordinates   959227..961446 (+) Length   739 a.a.
NCBI ID   WP_152562631.1    Uniprot ID   -
Organism   Neisseria meningitidis M7124     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 954227..966446
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA24_RS04955 (LA24_05225) comA 959227..961446 (+) 2220 WP_152562631.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LA24_RS04960 (LA24_05230) comL 961504..962307 (-) 804 WP_002221259.1 outer membrane protein assembly factor BamD Machinery gene
  LA24_RS04965 (LA24_05235) rluD 962306..963430 (+) 1125 WP_002221257.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  LA24_RS04970 (LA24_05240) - 963582..964529 (-) 948 WP_002221255.1 bile acid:sodium symporter family protein -
  LA24_RS04975 (LA24_05245) pgeF 965136..965915 (+) 780 WP_002221253.1 peptidoglycan editing factor PgeF -
  LA24_RS04980 (LA24_05250) lptE 965967..966446 (+) 480 WP_002214127.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 739 a.a.        Molecular weight: 79788.48 Da        Isoelectric Point: 10.1563

>NTDB_id=129042 LA24_RS04955 WP_152562631.1 959227..961446(+) (comA) [Neisseria meningitidis M7124]
MFRRWFLPCWVVGAAASFALPVVPHWLFWLAAFAVFAVFARRFAFAGLMLCVLAGAAYGVFRTEAALSSQWRAEAVSGVP
LTVEVADMPRSDGRRVQFAAKAVDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGIGGA
GTVGADRVLLHGGSGWGIAVWRSRISRNWQQADADGGLSDGIGLMRALSVGEQSALRPELWQAFRPLGLTHLVSISGLHV
TMVAVMFAWLAKRLLACSPRLPARPRAWVLAAGCAGALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALA
AVLLFDPSAVLGVGTWLSFGLVAALIWACSGRLHEGKRQTAVRGQWAASVLSLVLLGYLFASLPLISPLVNAVAIPWFSW
VLTPLALLGSVVPFAPLQQLGAFLAEYTLRFLVWLADVSPEFAVAAAPLPLLVLAVCAALLLLLPRGLGLRPWAVLLLAG
FVFYRSPGVPENEVAVTVWDAGQGLSVSVQTANHHLLFDTGTAAAAQMGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQA
VGKIPNGGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLMPSERKNIDDNGKSCVLRVVAGGAALLVTGDLDTKGEESLVG
KYGGNLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYANAYKHPTEAVQNRIRAHGIKLLRTDLSGALQFGLGRGG
VKAQRLRGYKFYWQKKPFE

Nucleotide


Download         Length: 2220 bp        

>NTDB_id=129042 LA24_RS04955 WP_152562631.1 959227..961446(+) (comA) [Neisseria meningitidis M7124]
GTGTTCCGTCGTTGGTTTTTGCCGTGTTGGGTTGTCGGCGCGGCGGCTTCGTTTGCGCTGCCGGTCGTGCCGCATTGGCT
GTTTTGGCTGGCGGCTTTTGCGGTTTTTGCTGTGTTTGCAAGGCGTTTTGCGTTTGCCGGTCTGATGCTGTGCGTGTTGG
CGGGCGCGGCTTACGGCGTATTCAGAACGGAAGCGGCACTGTCTTCGCAATGGCGGGCGGAGGCGGTTTCAGGTGTGCCG
TTGACGGTGGAAGTGGCGGATATGCCGAGGTCGGACGGGCGGCGCGTGCAGTTTGCGGCAAAGGCTGTGGACAGCGGTGG
TCGGACGTTTGATTTGCTGCTGTCGGACTACAAACGGCGCGAATGGGCGGTCGGGAGCAGATGGCGGATAACGGCACGTG
TGCACCCCGTCGTCGGCGAATTGAACCTGCGCGGTTTGAACCGTGAGGCGTGGGCATTATCCAACGGGATAGGCGGCGCG
GGGACGGTCGGTGCGGACAGGGTTTTGCTGCATGGCGGAAGCGGTTGGGGGATTGCGGTTTGGCGCAGCCGCATCAGCCG
TAATTGGCAGCAGGCGGATGCGGACGGCGGGCTTTCAGACGGCATCGGGCTGATGCGCGCGTTGAGCGTGGGCGAACAGT
CGGCATTGCGCCCCGAATTGTGGCAGGCGTTCCGGCCGTTGGGGCTGACGCATTTGGTCAGTATTTCGGGTTTGCACGTT
ACGATGGTGGCGGTAATGTTTGCGTGGCTGGCGAAGCGGCTGCTTGCCTGTTCCCCGCGCCTTCCTGCCCGGCCGCGTGC
GTGGGTTTTGGCGGCGGGGTGTGCAGGCGCGCTGTTTTACGCGCTGCTTGCCGGTTTTTCCGTGCCGACGCAGCGCAGCG
TTTTGATGTTGGCGGCGTTTGCGTGGGCTTGGCGCAGGGGAAGATTGTCGGCGTGGGCGACGTGGTGGCAGGCGTTGGCG
GCGGTGCTGCTGTTCGACCCGTCGGCGGTCTTGGGTGTGGGGACTTGGCTGTCTTTCGGTTTGGTGGCGGCCCTGATATG
GGCGTGTTCGGGGCGTTTGCACGAAGGGAAACGGCAAACCGCCGTGCGCGGGCAGTGGGCGGCTTCGGTGTTGTCGCTGG
TTTTGCTCGGTTATCTGTTTGCTTCGCTGCCTTTAATCAGCCCTTTGGTCAATGCGGTGGCGATTCCGTGGTTTTCTTGG
GTATTGACGCCGCTGGCGTTGCTGGGTTCGGTCGTGCCGTTTGCGCCTTTGCAACAGTTGGGGGCATTTTTGGCGGAATA
TACTTTGCGGTTTTTGGTGTGGCTTGCCGATGTGTCGCCCGAGTTTGCCGTTGCCGCCGCACCTTTGCCGCTGTTGGTGT
TGGCGGTGTGTGCCGCTTTGCTGTTGCTGCTGCCGCGCGGCTTGGGTTTGCGTCCGTGGGCGGTGTTGCTGTTGGCAGGG
TTTGTGTTTTACCGTTCACCCGGCGTGCCGGAAAATGAGGTTGCGGTTACGGTTTGGGATGCGGGGCAGGGTTTGTCGGT
GTCGGTTCAGACGGCAAATCATCATCTTTTGTTTGACACCGGAACGGCAGCGGCGGCGCAGATGGGGATTGTGCCGAGTT
TGAATGCGGCGGGTGTCCGCCGTTTGGACAAGCTGGTTCTGTCGCATCACGACAGCGACCACGACGGCGGTTTTCAGGCA
GTCGGCAAGATACCGAACGGCGGGATTTATGCCGGGCAGCCGGAATTTTATGAGGGGGCGCGGCATTGTGCGGAACAGCG
TTGGCAATGGGACGGCGTGGATTTTGAGTTTTTGATGCCGTCTGAACGCAAAAACATCGATGATAATGGGAAAAGTTGTG
TTTTGCGTGTTGTGGCGGGCGGTGCGGCACTGCTGGTAACGGGCGATTTGGATACGAAGGGCGAGGAAAGCCTGGTCGGC
AAGTATGGAGGCAACCTGTACAGCCAGGTTTTGGTTTTGGGACATCACGGCAGCAATACGTCCTCGTCGGGCGTGTTCCT
CAATGCCGTCTCGCCCGAATATGCCGTTGCTTCAAGCGGTTATGCCAACGCCTACAAACATCCGACCGAAGCGGTGCAAA
ACCGTATCCGTGCACACGGCATCAAATTGTTGCGTACCGATTTGTCGGGCGCGCTGCAATTCGGCTTGGGGCGCGGCGGC
GTGAAGGCTCAACGTTTGAGAGGGTATAAATTCTATTGGCAGAAAAAACCGTTTGAATGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(501-677)

Domain of unknown function (DUF4131) (DUF4131)

(8-167)

Competence protein (Competence)

(208-465)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

95.805

100

0.958

Multiple sequence alignment