Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LA50_RS04010 Genome accession   NZ_CP009418
Coordinates   726869..729958 (+) Length   1029 a.a.
NCBI ID   WP_079884993.1    Uniprot ID   -
Organism   Neisseria meningitidis strain NM3686     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 723621..753306 726869..729958 within 0


Gene organization within MGE regions


Location: 723621..753306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LA50_RS03985 (LA50_04190) - 723621..723851 (-) 231 WP_002216898.1 hypothetical protein -
  LA50_RS03990 (LA50_04195) - 724078..724278 (-) 201 WP_002212530.1 hypothetical protein -
  LA50_RS03995 (LA50_04200) - 724282..724593 (-) 312 WP_002212531.1 hypothetical protein -
  LA50_RS04000 (LA50_04205) - 724614..725822 (-) 1209 WP_002212532.1 replication initiation factor domain-containing protein -
  LA50_RS04010 (LA50_04215) pilC 726869..729958 (+) 3090 WP_079884993.1 PilC family type IV pilus tip adhesin Machinery gene
  LA50_RS04015 (LA50_04225) carA 731940..733073 (+) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  LA50_RS04020 (LA50_04230) - 733119..733256 (+) 138 WP_002214606.1 VOC family protein -
  LA50_RS04040 (LA50_04250) - 733836..734225 (+) 390 WP_002221514.1 DUF559 domain-containing protein -
  LA50_RS13810 - 734229..734396 (+) 168 WP_153312129.1 hypothetical protein -
  LA50_RS04050 (LA50_04260) - 734803..735366 (+) 564 WP_002214615.1 ComF family protein -
  LA50_RS04055 (LA50_04265) - 735369..735917 (+) 549 WP_002214617.1 hypothetical protein -
  LA50_RS04060 (LA50_04270) carB 735924..739139 (+) 3216 WP_002221515.1 carbamoyl-phosphate synthase large subunit -
  LA50_RS04065 (LA50_04275) crgA 739366..740265 (-) 900 WP_002214623.1 LysR family transcriptional regulator CrgA -
  LA50_RS04070 (LA50_04280) - 740504..741082 (+) 579 WP_002219825.1 NAD(P)H-dependent oxidoreductase -
  LA50_RS04080 (LA50_04290) queA 741453..742493 (-) 1041 WP_002226712.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  LA50_RS04085 (LA50_04295) - 742610..742867 (+) 258 WP_002254386.1 hypothetical protein -
  LA50_RS04090 (LA50_04300) accB 742849..743304 (+) 456 WP_002221517.1 acetyl-CoA carboxylase biotin carboxyl carrier protein -
  LA50_RS04095 (LA50_04305) accC 743416..744777 (+) 1362 WP_002221518.1 acetyl-CoA carboxylase biotin carboxylase subunit -
  LA50_RS04100 (LA50_04310) prmA 745038..745925 (+) 888 WP_002221520.1 50S ribosomal protein L11 methyltransferase -
  LA50_RS04105 (LA50_04315) orn 745943..746506 (+) 564 WP_002221521.1 oligoribonuclease -
  LA50_RS14355 - 746517..746660 (+) 144 WP_017201132.1 hypothetical protein -
  LA50_RS04110 (LA50_04325) hemL 746912..748195 (-) 1284 WP_002248132.1 glutamate-1-semialdehyde 2,1-aminomutase -
  LA50_RS14645 (LA50_04330) - 748259..748775 (-) 517 Protein_779 glucosamine-fructose-6-phosphate aminotransferase -
  LA50_RS04120 (LA50_04335) miaB 748978..750306 (+) 1329 WP_002234308.1 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB -
  LA50_RS04125 (LA50_04340) dxs 750391..752304 (-) 1914 WP_002248133.1 1-deoxy-D-xylulose-5-phosphate synthase -
  LA50_RS04130 (LA50_04345) xerC 752389..753306 (-) 918 WP_002248540.1 tyrosine recombinase XerC -

Sequence

Protein


Download         Length: 1029 a.a.        Molecular weight: 112444.34 Da        Isoelectric Point: 9.7895

>NTDB_id=128992 LA50_RS04010 WP_079884993.1 726869..729958(+) (pilC) [Neisseria meningitidis strain NM3686]
MNKTLKRRVFRHTALYAAILMFSHTGGGAQAETHNYAIVMNEQNQLKVKQKDSYSTLREKDRERKFIYNKGWQGGGSVLF
DNTDTLVSRQSGTAVFGTATYLPPYGKVSGFDANALKERNNAVDWIHTTRAGLAGYAYTNVICRSHQCPQLVYKTRFSFD
NPDLAKRGGGLDRHTEPSRDNSLIYKLKDHPWLGVSFNLGSENTVKNSQSSSRLISSFSEDNNNQTIVSTTENHPISLGD
GQREHTAVAYYLNAKLHLLDKKGIKDITGKTVRLGVLKPSIDVKTQRTGLGGLLGFHAKWDIKDTGQIPVELGLPQIKAG
RCINKPNPNPKAQALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSLKPLSTSEIK
SKEPTFTGRQTVIRLDGGVQQIKLQGNEVTSFNVNNGNNTFGIVKDLGVDPDASEWKKVLLPWTVRAFNNDGQFNTFNKE
ENNGKPKYSQKYRSRDNGKHERNLGDIVNSPIVAVGEYLATSANDGMVHIFKKNGGSDERSYNLKLSYIPGTMPRKDIES
KDSTLAKELRTFAEKGYVGDRYGVDGGFVLRQVELSGKKHVFMFGAMGFGGRGAYALDLTKADNGNPTAVSLFDVKNDNN
GKNSNNSVQLGYTVGTPQIGKTHDGKYAAFLASGYATKEITSGENTTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLVD
KDLDGTVDIAYAGDRGGSMYRFDLSSDNPSSWTVRTIFQGTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVLSTDEQHI
YGIFDNDTNTGTAQDGQGNGLLEQVLKKDGNTLFLSDYKRSNGSGDKGWVVKLEAGQRVTVKPTVVLRTAFVTIHKYTGN
DKCGAETAILGINTADGGKLTKKSARPIVPKANQAVAQYSGHKQTAKGKSIPIGCMEKDNGIVCPNGYVYDKPVNVRYLD
EKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSRKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3090 bp        

>NTDB_id=128992 LA50_RS04010 WP_079884993.1 726869..729958(+) (pilC) [Neisseria meningitidis strain NM3686]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGGGG
GGGGGCGCAGGCGGAAACCCATAACTACGCTATTGTCATGAACGAACAAAATCAGCTGAAGGTAAAGCAGAAGGATTCAT
ATTCAACCTTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATAATAAAGGCTGGCAGGGTGGAGGCTCTGTCTTGTTC
GACAATACCGATACCCTTGTTTCCCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGGCAA
GGTTTCCGGTTTTGATGCCAACGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCATACCACCCGGGCCGGGCTGG
CAGGCTACGCCTACACCAACGTCATATGCAGAAGCCACCAATGCCCCCAACTTGTCTATAAAACCCGATTTTCCTTCGAT
AATCCCGACTTGGCAAAAAGAGGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCGCGACAATTCGCTCATTTACAAATT
GAAGGATCATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATAGCCAATCATCCAGCAGAT
TGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAAACCACCCTATTTCCCTTGGCGAC
GGGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAAAGGGATTAAAGATAT
CACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGACACAAAGGACGGGGCTTGGCGGCTTGC
TAGGTTTTCATGCTAAGTGGGACATTAAAGATACCGGGCAGATTCCGGTCGAGCTCGGCCTGCCGCAAATCAAAGCAGGC
CGCTGCATCAACAAACCGAACCCCAATCCCAAAGCCCAAGCCCTTTCGCCGGCACTGACTGCCCCCGCGCTGTGGTTCGG
ACCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCAAATTTTCC
TGCAAAACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTACGTCGGAGATTAAA
AGTAAAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATGGCGGCGTACAGCAGATTAAACTTCAAGGCAA
TGAGGTCACTAGTTTTAATGTAAACAACGGCAACAACACTTTCGGCATTGTTAAGGACTTGGGCGTCGATCCTGATGCCA
GCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTTCAATAATGACGGTCAATTTAACACATTCAACAAAGAA
GAAAACAACGGCAAGCCAAAATACAGCCAAAAATACCGCAGCCGCGACAACGGCAAGCACGAGCGCAATTTGGGCGACAT
CGTCAACAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAAAAAA
ACGGCGGCAGTGATGAACGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCAAGGATATTGAAAGC
AAAGACTCCACCCTTGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGG
CTTTGTTTTGCGCCAAGTCGAACTGAGCGGGAAAAAACACGTGTTTATGTTCGGCGCGATGGGTTTTGGCGGCAGAGGTG
CATACGCCTTGGATTTGACCAAAGCCGACAACGGCAACCCAACCGCCGTTTCCCTGTTTGATGTCAAAAATGACAATAAT
GGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACGACGGCAAATA
CGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAGAAATTACCAGCGGCGAGAATACAACCGCGCTGTATGTGTATGATT
TGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGTACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGAT
AAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGCAGTATGTATCGCTTTGATTTGAGCAGCGA
CAATCCGTCCAGCTGGACTGTACGCACTATTTTCCAAGGCACGAAGCCGATTACTTCCGCGCCCGCCATTTCCCAACTGA
AAGACAAACGCGTGGTTATCTTCGGCACGGGCAGTGATTTGAGTGAGGATGATGTACTCAGTACGGATGAACAACATATT
TACGGTATTTTTGACAATGACACAAACACGGGTACGGCGCAAGACGGGCAGGGCAACGGGCTGCTCGAGCAAGTGCTGAA
AAAAGACGGCAATACGCTGTTCTTAAGCGACTACAAAAGGTCTAACGGCTCGGGCGATAAGGGCTGGGTAGTGAAATTGG
AAGCCGGACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCATAAATATACGGGTAAT
GACAAATGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCC
GATTGTGCCGAAAGCCAATCAGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCGCCAAAGGCAAATCCATCCCTATAG
GTTGTATGGAAAAAGACAATGGAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGAC
GAAAAGAAAACAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACC
CGCCCGCAATAACCGGTGCTTCTCCAGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCG
GCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(504-837)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

78.044

100

0.791

Multiple sequence alignment