Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   KQ76_RS10345 Genome accession   NZ_CP009361
Coordinates   2063497..2064213 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain ATCC 25923     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2058497..2069213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ76_RS10315 (KQ76_10505) - 2058710..2059336 (+) 627 WP_000522388.1 nitroreductase family protein -
  KQ76_RS10320 (KQ76_10510) - 2059697..2060482 (+) 786 WP_000867948.1 carbon-nitrogen family hydrolase -
  KQ76_RS15305 hld 2061084..2061164 (-) 81 WP_000046022.1 delta-hemolysin -
  KQ76_RS10330 (KQ76_10520) - 2061454..2062017 (+) 564 WP_001105709.1 accessory gene regulator AgrB -
  KQ76_RS10335 (KQ76_10525) agrD 2062021..2062161 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  KQ76_RS10340 (KQ76_10530) agrC 2062186..2063478 (+) 1293 WP_000387810.1 quorum-sensing sensor histidine kinase AgrC -
  KQ76_RS10345 (KQ76_10535) agrA 2063497..2064213 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  KQ76_RS10350 (KQ76_10540) - 2064587..2065546 (-) 960 WP_001253292.1 carbohydrate kinase family protein -
  KQ76_RS10355 (KQ76_10545) - 2065543..2067027 (-) 1485 WP_001791588.1 sucrose-6-phosphate hydrolase -
  KQ76_RS10360 (KQ76_10550) - 2067176..2068126 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=128926 KQ76_RS10345 WP_000688492.1 2063497..2064213(+) (agrA) [Staphylococcus aureus strain ATCC 25923]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=128926 KQ76_RS10345 WP_000688492.1 2063497..2064213(+) (agrA) [Staphylococcus aureus strain ATCC 25923]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATCAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAAAGATAATAGCGTTGAAACGATTGAGTTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTCAGATGTCATAATAGCTTTGTCGTCAATCGTCATAATATCGAATCTATTG
ATTCGAAAGAGCGTATTGTTTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment