Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   AA958_RS18270 Genome accession   NZ_CP011492
Coordinates   4287330..4289858 (+) Length   842 a.a.
NCBI ID   WP_047017130.1    Uniprot ID   -
Organism   Streptomyces sp. CNQ-509     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 4282330..4294858
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AA958_RS18235 (AA958_18235) - 4282647..4283444 (+) 798 WP_047017125.1 type III pantothenate kinase -
  AA958_RS18240 (AA958_18240) - 4283564..4284370 (+) 807 WP_047017126.1 hypothetical protein -
  AA958_RS37165 (AA958_18245) - 4284522..4284692 (+) 171 WP_047017127.1 hypothetical protein -
  AA958_RS18250 (AA958_18250) - 4284817..4285221 (+) 405 WP_047017128.1 BlaI/MecI/CopY family transcriptional regulator -
  AA958_RS18255 (AA958_18255) - 4285237..4285755 (+) 519 WP_047017129.1 amino-acid N-acetyltransferase -
  AA958_RS35415 (AA958_18260) - 4285876..4286202 (+) 327 WP_027754213.1 Lsr2 family protein -
  AA958_RS37695 (AA958_18265) - 4286141..4286878 (-) 738 WP_186462010.1 hypothetical protein -
  AA958_RS18270 (AA958_18270) clpC 4287330..4289858 (+) 2529 WP_047017130.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  AA958_RS18275 (AA958_18275) - 4290161..4291159 (-) 999 WP_047017131.1 alpha/beta hydrolase -
  AA958_RS18280 (AA958_18280) - 4291260..4291577 (-) 318 WP_047017132.1 putative quinol monooxygenase -
  AA958_RS18285 (AA958_18285) - 4291722..4292627 (+) 906 WP_047017133.1 AraC family transcriptional regulator -
  AA958_RS18290 (AA958_18290) - 4292786..4293535 (+) 750 WP_047020191.1 SDR family oxidoreductase -
  AA958_RS18295 (AA958_18295) - 4293984..4294544 (-) 561 WP_047017134.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 842 a.a.        Molecular weight: 93018.99 Da        Isoelectric Point: 5.3062

>NTDB_id=128537 AA958_RS18270 WP_047017130.1 4287330..4289858(+) (clpC) [Streptomyces sp. CNQ-509]
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYQGGKETATAGGPAEG
TPSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLK
DKHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGAT
TLDEYRKHLEKDAALERRFQPIQVAEPSLQHTIEILKGLRDRYEAHHRVSITDAALVAAAQLADRYISDRFLPDKAIDLI
DEAGSRMRIRRMTAPPDLREFDEKIADVRREKESAIDSQDFELAAGLRDKEKQLLAQKAQREKEWKAGDMDVVAEVDEEL
IAEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQEDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELS
KTLAEFLFGDEDALIQLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILE
DGRLTDSQGRVVDFKNTIIIMTTNLGTKDISKGFGLGFAAGGDVKSGYERMKSKVSEELKQHFRPEFLNRVDDIVVFHQL
TRDDIIEIVDLRLAELDNRLKDRDMAIELSTEAKDLLSKRGFDPVLGARPLRRAIQREIEDVLSEKILFGELRPGHIVVV
DTEGEGDDATFTFRGEEKSALPDAPPVDAAAGGAGPNLSKEA

Nucleotide


Download         Length: 2529 bp        

>NTDB_id=128537 AA958_RS18270 WP_047017130.1 4287330..4289858(+) (clpC) [Streptomyces sp. CNQ-509]
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCCTGATCCACGAGGGTGAGGGTGTCGCCGCAAAGGCACTGGAGAGCCTCGGGA
TCTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGCCAGGGCCAGCAGGCCCCGTCCGGCCACATCCCCTTC
ACGCCCCGGGCGAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCCCTCCAGCTCGGCCACAACTACATCGGCACGGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTCGTGAAGCTGGGCGCCGACCTGAACCGGG
TGCGGCAGCAGGTCATCCAGCTGCTCTCCGGCTACCAGGGCGGCAAGGAGACCGCCACGGCCGGCGGCCCCGCCGAGGGC
ACGCCGTCGACGTCCCTGGTGCTCGACCAGTTCGGCCGGAACCTCACGCAGGCCGCCCGCGAGTCCAAGCTCGACCCGGT
CATCGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGGACGAAGAACAACCCCGTCCTCATCGGCG
AGCCCGGCGTCGGCAAGACCGCCGTCGTCGAGGGCCTGGCGCAGGCCATCGTCAAGGGCGAGGTGCCCGAGACGCTGAAG
GACAAGCACCTCTACACCCTGGACCTCGGCGCCCTGGTCGCGGGCTCCCGCTACCGCGGTGACTTCGAGGAGCGCCTGAA
GAAGGTGCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACCCTGGTGGGCGCGGGGG
CCGCCGAGGGCGCGATCGACGCGGCGAGCATCCTCAAGCCGATGCTGGCCCGCGGCGAGCTGCAGACCATCGGCGCCACC
ACGCTCGACGAGTACCGCAAGCACCTGGAGAAGGACGCGGCCCTGGAGCGCCGCTTCCAGCCGATCCAGGTCGCGGAGCC
GTCGCTGCAGCACACCATCGAGATCCTCAAGGGTCTGCGCGACCGGTACGAGGCGCACCACCGGGTGTCCATCACGGACG
CCGCGCTGGTCGCCGCGGCCCAGCTCGCCGACCGGTACATCTCCGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATC
GACGAGGCGGGCTCGCGGATGCGTATCCGCCGGATGACCGCACCGCCGGACCTGCGGGAGTTCGACGAGAAGATCGCCGA
CGTGCGGCGCGAGAAGGAGTCCGCGATCGACTCGCAGGACTTCGAGCTGGCCGCAGGGCTGCGCGACAAGGAGAAGCAGC
TCCTGGCGCAGAAGGCGCAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTGGACGAGGAGCTC
ATCGCCGAGGTCCTGGCCACCGCCACCGGCATCCCGGTCTTCAAGCTGACCGAGGAGGAGTCCTCGCGGCTGCTGCGCAT
GGAGGACGAGCTGCACAAGCGCGTCATCGGGCAGGAGGACGCCATCAAGGCGCTCTCCCAGGCCATCCGGCGTACGCGGG
CGGGCCTGAAGGACCCGAAGCGCCCCGGCGGTTCGTTCATCTTCGCCGGCCCGTCCGGCGTCGGTAAGACGGAGCTGTCG
AAGACGCTGGCGGAGTTCCTCTTCGGTGACGAGGACGCGCTCATCCAGCTCGACATGTCGGAGTTCAGCGAGAAGCACAC
CGTCTCGCGGCTGTTCGGCTCCCCGCCCGGCTACGTCGGGTACGAGGAGGGCGGTCAGCTCACCGAGAAGGTGCGCCGGA
AGCCGTTCTCCGTGGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCGGACATCTTCAACTCGCTGCTGCAGATCCTGGAG
GACGGTCGCCTGACCGACTCCCAGGGCCGGGTCGTGGACTTCAAGAACACGATCATCATCATGACGACCAACCTCGGCAC
CAAGGACATCTCCAAGGGCTTCGGCCTGGGGTTCGCCGCCGGGGGCGACGTCAAGAGCGGCTACGAGCGGATGAAGTCCA
AGGTCAGCGAGGAGCTCAAGCAGCACTTCCGGCCCGAGTTCCTCAACCGTGTGGACGACATCGTGGTCTTCCACCAGCTC
ACCAGGGACGACATCATCGAGATCGTCGACCTGCGGCTGGCCGAGCTGGACAACCGGCTCAAGGACCGCGACATGGCCAT
CGAGCTCTCCACCGAGGCGAAGGACCTGCTCTCCAAGCGGGGCTTCGACCCGGTGCTGGGCGCCCGGCCGCTGCGCCGCG
CGATCCAGCGGGAGATCGAGGACGTGCTCTCGGAGAAGATCCTCTTCGGCGAGCTGCGCCCGGGCCACATCGTGGTGGTC
GACACCGAGGGCGAGGGTGACGACGCGACGTTCACCTTCCGCGGCGAGGAGAAGTCGGCACTGCCCGACGCCCCGCCGGT
CGACGCCGCCGCGGGCGGCGCGGGCCCGAACCTGAGCAAGGAGGCGTGA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(349-449)

ATPase family associated with various cellular activities (AAA) (AAA)

(210-330)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(720-800)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(93-142)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(16-68)

AAA domain (Cdc48 subfamily) (AAA_2)

(542-714)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

61.05

97.268

0.594
  clpC Streptococcus mutans UA159

44.578

98.575

0.439
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

44.857

95.843

0.43
  clpC Streptococcus thermophilus LMG 18311

42.925

99.881

0.429
  clpC Streptococcus thermophilus LMD-9

42.925

99.881

0.429
  clpC Streptococcus pneumoniae D39

44.11

94.774

0.418
  clpC Streptococcus pneumoniae Rx1

44.11

94.774

0.418
  clpC Streptococcus pneumoniae TIGR4

44.136

94.181

0.416
  clpE Streptococcus pneumoniae TIGR4

51.887

75.534

0.392
  clpE Streptococcus mutans UA159

52.809

73.99

0.391
  clpE Streptococcus pneumoniae R6

51.572

75.534

0.39
  clpE Streptococcus pneumoniae D39

51.572

75.534

0.39
  clpE Streptococcus pneumoniae Rx1

51.572

75.534

0.39
  clpC Lactococcus lactis subsp. cremoris KW2

51.935

73.634

0.382

Multiple sequence alignment