Detailed information NTG0128349

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: AW22_RS03355
• Genome accession: NZ_CP009300
• Coordinates: 421559..422353 (+)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus cereus D17
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 416559..427353

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AW22_RS03340 (AW22_450)	argR	417398..417847 (+)	450	WP_001032581.1	arginine repressor ArgR	-
AW22_RS03345 (AW22_451)	recN	418115..419854 (+)	1740	WP_000947754.1	DNA repair protein RecN	Machinery gene
AW22_RS03350 (AW22_452)	spoIVB	419973..421271 (+)	1299	WP_002054681.1	SpoIVB peptidase	-
AW22_RS03355 (AW22_453)	spo0A	421559..422353 (+)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
AW22_RS03360 (AW22_454)	-	422651..424177 (+)	1527	WP_042510872.1	glycosyltransferase family 39 protein	-
AW22_RS03365 (AW22_455)	-	424345..424491 (-)	147	WP_001247671.1	YycC family protein	-
AW22_RS03370 (AW22_456)	-	424542..425270 (+)	729	WP_000172561.1	glycerophosphodiester phosphodiesterase	-
AW22_RS03375 (AW22_457)	-	425319..425552 (-)	234	WP_001190187.1	DUF2627 domain-containing protein	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=128349 AW22_RS03355 WP_003161566.1 421559..422353(+) (spo0A) [Bacillus cereus D17]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=128349 AW22_RS03355 WP_003161566.1 421559..422353(+) (spo0A) [Bacillus cereus D17]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCGAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGACATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCCGATAAGTTGAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818