Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HPYLSS1_RS02665 Genome accession   NZ_CP009259
Coordinates   529248..531032 (-) Length   594 a.a.
NCBI ID   WP_077231942.1    Uniprot ID   -
Organism   Helicobacter pylori SS1     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 524248..536032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPYLSS1_RS02635 (HPYLSS1_00508) - 524634..524882 (+) 249 WP_000790557.1 RNA-binding protein -
  HPYLSS1_RS02640 (HPYLSS1_00509) - 525100..525921 (-) 822 WP_077231939.1 glycosyltransferase family 25 protein -
  HPYLSS1_RS02645 (HPYLSS1_00510) trxB 526274..527209 (-) 936 WP_077231940.1 thioredoxin-disulfide reductase -
  HPYLSS1_RS02650 (HPYLSS1_00511) trxA 527215..527535 (-) 321 WP_000020199.1 thioredoxin -
  HPYLSS1_RS02655 (HPYLSS1_00512) - 527626..527970 (-) 345 WP_001211689.1 YraN family protein -
  HPYLSS1_RS02660 (HPYLSS1_00513) - 527971..529236 (-) 1266 WP_077231941.1 homoserine dehydrogenase -
  HPYLSS1_RS02665 (HPYLSS1_00514) uvrC 529248..531032 (-) 1785 WP_077231942.1 excinuclease ABC subunit UvrC Machinery gene
  HPYLSS1_RS02670 (HPYLSS1_00515) - 531033..531494 (-) 462 WP_039092475.1 hypothetical protein -
  HPYLSS1_RS02675 - 531486..531665 (+) 180 WP_000468793.1 hypothetical protein -
  HPYLSS1_RS02680 (HPYLSS1_00516) - 531677..532318 (-) 642 WP_077231943.1 ATP-binding cassette domain-containing protein -
  HPYLSS1_RS02685 (HPYLSS1_00517) - 532320..533981 (-) 1662 WP_077231944.1 ABC transporter permease/substrate-binding protein -
  HPYLSS1_RS02690 (HPYLSS1_00518) - 534050..534487 (-) 438 WP_001885597.1 hypothetical protein -
  HPYLSS1_RS02695 (HPYLSS1_00519) motB 534493..535266 (-) 774 WP_077231945.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68689.95 Da        Isoelectric Point: 9.7528

>NTDB_id=127787 HPYLSS1_RS02665 WP_077231942.1 529248..531032(-) (uvrC) [Helicobacter pylori SS1]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKNRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEVLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSSEDRILEEARSLFKLECVPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=127787 HPYLSS1_RS02665 WP_077231942.1 529248..531032(-) (uvrC) [Helicobacter pylori SS1]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCGAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCATCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAATGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAAACAGACTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGCGGGAACAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAGC
GCTTGCTCTAATGAGGTGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAACATCCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
GTGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCTAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAACGCCTTCCAAAAAAATTCTTATCGGCG
CTACCATCTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGAGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATCAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTGAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(206-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.306

100

0.973

Multiple sequence alignment