Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   U069_RS19375 Genome accession   NZ_CP011343
Coordinates   3918967..3919959 (+) Length   330 a.a.
NCBI ID   WP_000224470.1    Uniprot ID   P0ACQ1
Organism   Escherichia coli K-12 substr. GM4792     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 3913967..3924959
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U069_RS19350 (U069_c0138) rbsD 3914091..3914510 (+) 420 WP_001301979.1 D-ribose pyranase -
  U069_RS19355 (U069_c0139) rbsA 3914518..3916023 (+) 1506 WP_000387770.1 ribose ABC transporter ATP-binding protein RbsA -
  U069_RS19360 (U069_c0140) rbsC 3916028..3916993 (+) 966 WP_000211858.1 ribose ABC transporter permease -
  U069_RS19365 (U069_c0141) rbsB 3917018..3917908 (+) 891 WP_001056271.1 ribose ABC transporter substrate-binding protein RbsB -
  U069_RS19370 (U069_c0142) rbsK 3918034..3918963 (+) 930 WP_001300603.1 ribokinase -
  U069_RS19375 (U069_c0143) cytR 3918967..3919959 (+) 993 WP_000224470.1 ribose operon transcriptional repressor RbsR Regulator
  U069_RS19380 (U069_c0144) mdtD 3919925..3921352 (-) 1428 WP_001280852.1 multidrug transporter subunit MdtD -
  U069_RS19385 (U069_c0145) yieP 3921375..3922067 (-) 693 WP_001131164.1 FadR/GntR family transcriptional regulator -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36611.90 Da        Isoelectric Point: 5.2141

>NTDB_id=127786 U069_RS19375 WP_000224470.1 3918967..3919959(+) (cytR) [Escherichia coli K-12 substr. GM4792]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=127786 U069_RS19375 WP_000224470.1 3918967..3919959(+) (cytR) [Escherichia coli K-12 substr. GM4792]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACCGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCTCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTCGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAACCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACTGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATCGCCTGTATTACCGGCCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCTATGCGCCAACTGCTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACCACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTTCAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGCGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364

Multiple sequence alignment