Detailed information NTG0127614

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: AAF13_RS21825
• Genome accession: NZ_CP011331
• Coordinates: 4333221..4334246 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644897.1
• Uniprot ID: B7LA31
• Organism: Escherichia coli O104:H4 str. C227-11 isolate 368 shch
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4328221..4339246

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAF13_RS21815 (AAF13_21815)	rpmE	4330452..4330664 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
AAF13_RS21820 (AAF13_21820)	priA	4330867..4333065 (+)	2199	WP_001350069.1	primosomal protein N'	Machinery gene
AAF13_RS21825 (AAF13_21825)	cytR	4333221..4334246 (+)	1026	WP_000644897.1	DNA-binding transcriptional regulator CytR	Regulator
AAF13_RS21830 (AAF13_21830)	ftsN	4334338..4335297 (+)	960	WP_000068834.1	cell division protein FtsN	-
AAF13_RS21835 (AAF13_21835)	hslV	4335390..4335920 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
AAF13_RS21840 (AAF13_21840)	hslU	4335930..4337261 (+)	1332	WP_001293343.1	HslU--HslV peptidase ATPase subunit	-
AAF13_RS21845 (AAF13_21845)	menA	4337328..4338254 (+)	927	WP_001307494.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
AAF13_RS21850 (AAF13_21850)	rraA	4338347..4338832 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
AAF13_RS21855 (AAF13_21855)	zapB	4338917..4339162 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37800.74 Da
• Isoelectric Point: 6.3001

>NTDB_id=127614 AAF13_RS21825 WP_000644897.1 4333221..4334246(+) (cytR) [Escherichia coli O104:H4 str. C227-11 isolate 368 shch]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALHRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=127614 AAF13_RS21825 WP_000644897.1 4333221..4334246(+) (cytR) [Escherichia coli O104:H4 str. C227-11 isolate 368 shch]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTCGCACCGGAACTGGAG
CTACCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCACTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCATCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: B7LA31

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	63.881	98.24	0.628
cytR	Vibrio cholerae C6706	65.138	95.894	0.625