Detailed information NTG0127477

Bioinformatically predicted

Overview

• Name: pilC
• Type: Machinery gene
• Locus tag: JT17_RS05910
• Genome accession: NZ_CP009237
• Coordinates: 1221868..1223064 (-)
• Length: 398 a.a.
• NCBI ID: WP_005711777.1
• Uniprot ID: B8F826
• Organism: Glaesserella parasuis strain KL0318
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1216868..1228064

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JT17_RS05885 (JT17_06090)	-	1217584..1217973 (-)	390	WP_005711765.1	SufE family protein	-
JT17_RS05890 (JT17_06095)	clpP	1218074..1218655 (+)	582	WP_044009240.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	-
JT17_RS05895 (JT17_06100)	clpX	1218662..1219912 (+)	1251	WP_044009241.1	ATP-dependent protease ATP-binding subunit ClpX	-
JT17_RS05900 (JT17_06105)	dapE	1219986..1221119 (-)	1134	WP_044009242.1	succinyl-diaminopimelate desuccinylase	-
JT17_RS05905 (JT17_06110)	-	1221203..1221871 (-)	669	WP_044009243.1	prepilin peptidase	-
JT17_RS05910 (JT17_06115)	pilC	1221868..1223064 (-)	1197	WP_005711777.1	type II secretion system F family protein	Machinery gene
JT17_RS05915 (JT17_06120)	pilB	1223057..1224442 (-)	1386	WP_044009244.1	GspE/PulE family protein	Machinery gene
JT17_RS05920 (JT17_06125)	pilA	1224490..1224954 (-)	465	WP_005711781.1	pilin	Machinery gene
JT17_RS05925 (JT17_06130)	radA	1225142..1226518 (+)	1377	WP_021110380.1	DNA repair protein RadA	-
JT17_RS05930 (JT17_06135)	gmk	1226571..1227197 (-)	627	WP_035491622.1	guanylate kinase	-

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 45575.38 Da
• Isoelectric Point: 10.1129

>NTDB_id=127477 JT17_RS05910 WP_005711777.1 1221868..1223064(-) (pilC) [Glaesserella parasuis strain KL0318]
MNNIYEFQWKGRNRFGQKQTGRQLAESREVLEKRLQQKGYSQLSISRHFALPTAPKKEEINQFMQQLALLIQAKIPLKQS
LVMLLETCQNRTFYRWQQETIRLIEAGFALSVAFKKQGKYINPQEIQLIKMAETSGNLGLILTNIAQRREKSEKLAKKIK
KILFYPVFILAISITLSILLLLFIVPQFAELYGSKGKSLPLITEILFSLSHFLQHSILTLIILCVLCFLLIHILNKKTDL
IKRLKFIILSHIPILKGIIQYSRIIFFCQNSSLMLASHIRLDTVLHSFLANKSDDILLQGSLATTLTYLKQGYRLADSLD
PKLFPTDMLQMIAIGEQSGKLSPMLQQISDGYQQRLDYQIDILSQLLEPMLMVLMGIIVGTILVGLYLPIFDMGAMIE

Nucleotide

• Length: 1197 bp

>NTDB_id=127477 JT17_RS05910 WP_005711777.1 1221868..1223064(-) (pilC) [Glaesserella parasuis strain KL0318]
ATGAATAACATTTATGAATTTCAATGGAAAGGACGCAACCGCTTTGGGCAAAAGCAGACAGGGCGACAGCTTGCCGAAAG
CCGAGAAGTGCTAGAGAAACGGTTGCAACAAAAAGGATACAGCCAGTTAAGCATTAGCCGACATTTTGCCTTGCCGACTG
CACCAAAAAAGGAAGAAATTAATCAATTTATGCAACAGTTAGCCTTATTAATTCAAGCTAAAATCCCCCTAAAACAGAGT
TTAGTGATGTTGCTTGAAACCTGCCAAAATCGCACTTTTTACCGTTGGCAACAAGAAACAATCCGCTTGATTGAAGCCGG
CTTTGCGTTATCCGTTGCCTTTAAAAAACAGGGAAAATATATTAATCCACAAGAAATCCAATTAATTAAAATGGCAGAAA
CAAGCGGTAATTTAGGGCTAATTTTAACCAATATTGCACAACGCCGTGAAAAATCGGAAAAATTAGCCAAGAAAATTAAA
AAAATTCTCTTTTATCCCGTCTTTATTTTAGCTATTTCAATCACACTCTCTATTTTATTATTGCTTTTTATTGTGCCACA
ATTTGCAGAACTTTATGGTTCAAAAGGAAAATCACTCCCTCTAATTACCGAAATACTCTTTAGCCTATCCCATTTTCTAC
AACACTCTATTTTAACGCTAATTATTTTATGTGTATTATGTTTTCTATTAATTCATATTTTAAATAAAAAAACAGATCTT
ATTAAACGCCTAAAGTTTATTATATTAAGCCATATTCCTATTTTAAAAGGCATTATCCAGTATTCACGCATTATCTTTTT
TTGTCAAAATAGCAGTTTAATGCTGGCTTCACATATTCGTTTAGATACTGTACTTCATTCCTTTTTAGCCAATAAAAGTG
ATGATATTTTATTACAAGGTTCTCTAGCAACTACACTAACTTATTTAAAACAAGGCTATCGTTTAGCCGACAGTTTAGAT
CCAAAACTCTTTCCTACGGATATGTTACAGATGATTGCCATTGGCGAGCAGAGCGGAAAATTATCGCCAATGTTGCAACA
AATCAGCGACGGTTATCAACAGCGGTTAGATTATCAAATTGATATACTTTCCCAATTATTAGAGCCGATGTTAATGGTGT
TAATGGGAATTATTGTAGGAACTATTTTAGTCGGTTTGTATTTGCCGATTTTTGATATGGGAGCAATGATAGAATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (63-186)

• Type II secretion system (T2SS), protein F (T2SSF) (267-389)

3D structure

• AlphaFold DB: B8F826

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilC	Glaesserella parasuis strain SC1401	100	100	1
pilC	Haemophilus influenzae 86-028NP	38.155	100	0.384
pilC	Haemophilus influenzae Rd KW20	38.155	100	0.384