Detailed information NTG0127214

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: SG46_RS18955
• Genome accession: NZ_CP011322
• Coordinates: 3918455..3919447 (+)
• Length: 330 a.a.
• NCBI ID: WP_000224470.1
• Uniprot ID: P0ACQ1
• Organism: Escherichia coli strain SQ110
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 3913455..3924447

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SG46_RS18930 (SG46_3807)	rbsD	3913579..3913998 (+)	420	WP_001301979.1	D-ribose pyranase	-
SG46_RS18935 (SG46_3808)	rbsA	3914006..3915511 (+)	1506	WP_000387770.1	ribose ABC transporter ATP-binding protein RbsA	-
SG46_RS18940 (SG46_3809)	rbsC	3915516..3916481 (+)	966	WP_000211858.1	ribose ABC transporter permease	-
SG46_RS18945 (SG46_3810)	rbsB	3916506..3917396 (+)	891	WP_001056271.1	ribose ABC transporter substrate-binding protein RbsB	-
SG46_RS18950 (SG46_3811)	rbsK	3917522..3918451 (+)	930	WP_001300603.1	ribokinase	-
SG46_RS18955 (SG46_3812)	cytR	3918455..3919447 (+)	993	WP_000224470.1	ribose operon transcriptional repressor RbsR	Regulator
SG46_RS18960 (SG46_3813)	mdtD	3919413..3920840 (-)	1428	WP_001280852.1	multidrug transporter subunit MdtD	-
SG46_RS18965 (SG46_3814)	yieP	3920863..3921555 (-)	693	WP_001131164.1	FadR/GntR family transcriptional regulator	-
SG46_RS18970 (SG46_3815)	hdfR	3921757..3922596 (-)	840	WP_000379245.1	HTH-type transcriptional regulator HdfR	-
SG46_RS18975 (SG46_3816)	maoP	3922715..3923053 (+)	339	WP_000841001.1	macrodomain Ori organization protein MaoP	-

Sequence

Protein

• Length: 330 a.a.
• Molecular weight: 36611.90 Da
• Isoelectric Point: 5.2141

>NTDB_id=127214 SG46_RS18955 WP_000224470.1 3918455..3919447(+) (cytR) [Escherichia coli strain SQ110]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide

• Length: 993 bp

>NTDB_id=127214 SG46_RS18955 WP_000224470.1 3918455..3919447(+) (cytR) [Escherichia coli strain SQ110]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACCGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCTCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACCAATCCTTTCTATTCAGAACTGGTGCGTGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTCGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAACCTTCGCGTGAAATCA
TGCAACGTTATCCGACAGTGCCTACTGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATCGCCTGTATTACCGGCCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCTATGCGCCAACTGCTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACCACTATCCACCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTTCAGCAACAACGATTACAACTT
ACTCCGATTCTGATGGAACGCGGTTCGGCTTAG

Domains

Predicted by InterProScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (169-329)

• Bacterial regulatory proteins, lacI family (LacI) (3-48)

3D structure

• AlphaFold DB: P0ACQ1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	37.048	100	0.373
cytR	Vibrio cholerae C6706	39.088	93.03	0.364