Detailed information NTG0126089

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: VT08_RS08595
• Genome accession: NZ_CP011069
• Coordinates: 1774620..1775387 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain STAB09014
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1769620..1780387

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VT08_RS08585 (VT08_08600)	hexB	1770138..1772120 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
VT08_RS08590 (VT08_08605)	-	1772215..1773366 (-)	1152	WP_003058754.1	tyrosine-type recombinase/integrase	-
VT08_RS09950	-	1773615..1773758 (+)	144	WP_011185066.1	putative holin-like toxin	-
VT08_RS08595 (VT08_08610)	irvR	1774620..1775387 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
VT08_RS08600 (VT08_08615)	-	1775541..1775747 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
VT08_RS08605 (VT08_08620)	-	1775781..1775981 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
VT08_RS08610 (VT08_08625)	-	1776002..1776409 (+)	408	WP_002992501.1	hypothetical protein	-
VT08_RS09955	-	1776422..1776544 (+)	123	WP_011285272.1	hypothetical protein	-
VT08_RS08615 (VT08_08630)	-	1776827..1777348 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
VT08_RS08620 (VT08_08635)	-	1777596..1777769 (+)	174	WP_000132665.1	hypothetical protein	-
VT08_RS08625 (VT08_08640)	-	1777987..1778160 (+)	174	WP_000074663.1	plasmid mobilization protein	-
VT08_RS08630 (VT08_08645)	-	1778322..1778753 (+)	432	WP_136302445.1	hypothetical protein	-
VT08_RS08635 (VT08_08650)	-	1778855..1779187 (+)	333	WP_011285276.1	hypothetical protein	-
VT08_RS08640 (VT08_08655)	-	1779187..1779378 (+)	192	WP_021340709.1	hypothetical protein	-
VT08_RS08645 (VT08_08660)	-	1779390..1779719 (+)	330	WP_003058810.1	hypothetical protein	-
VT08_RS08650 (VT08_08665)	-	1779722..1779994 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=126089 VT08_RS08595 WP_003058809.1 1774620..1775387(-) (irvR) [Streptococcus pyogenes strain STAB09014]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=126089 VT08_RS08595 WP_003058809.1 1774620..1775387(-) (irvR) [Streptococcus pyogenes strain STAB09014]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4