Detailed information NTG0125997

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: VU19_RS09100
• Genome accession: NZ_CP011068
• Coordinates: 1862983..1863750 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain STAB10015
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1857983..1868750

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VU19_RS09090 (VU19_09085)	hexB	1858501..1860483 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
VU19_RS09095 (VU19_09090)	-	1860578..1861729 (-)	1152	WP_003058754.1	site-specific integrase	-
VU19_RS10695	-	1861978..1862121 (+)	144	WP_011185066.1	putative holin-like toxin	-
VU19_RS09100 (VU19_09095)	irvR	1862983..1863750 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
VU19_RS09105 (VU19_09100)	-	1863904..1864110 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
VU19_RS09110 (VU19_09105)	-	1864144..1864344 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
VU19_RS09115 (VU19_09110)	-	1864365..1864772 (+)	408	WP_002992501.1	hypothetical protein	-
VU19_RS10700	-	1864785..1864907 (+)	123	WP_011285272.1	hypothetical protein	-
VU19_RS09120 (VU19_09115)	-	1865190..1865711 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
VU19_RS09125 (VU19_09120)	-	1865959..1866132 (+)	174	WP_000132665.1	hypothetical protein	-
VU19_RS09130 (VU19_09125)	-	1866294..1866725 (+)	432	WP_136302445.1	hypothetical protein	-
VU19_RS09135 (VU19_09130)	-	1866827..1867159 (+)	333	WP_011285276.1	hypothetical protein	-
VU19_RS09140 (VU19_09135)	-	1867159..1867350 (+)	192	WP_021340709.1	hypothetical protein	-
VU19_RS09145 (VU19_09140)	-	1867362..1867691 (+)	330	WP_003058810.1	hypothetical protein	-
VU19_RS09150 (VU19_09145)	-	1867694..1867966 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=125997 VU19_RS09100 WP_003058809.1 1862983..1863750(-) (irvR) [Streptococcus pyogenes strain STAB10015]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=125997 VU19_RS09100 WP_003058809.1 1862983..1863750(-) (irvR) [Streptococcus pyogenes strain STAB10015]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4