Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   FORC12_RS06545 Genome accession   NZ_CP010998
Coordinates   1251744..1252457 (+) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain FORC_012 isolate human sputum     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1246744..1257457
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC12_RS14470 - 1247947..1248210 (-) 264 WP_001205732.1 hypothetical protein -
  FORC12_RS06490 (FORC12_1165) - 1248219..1248479 (-) 261 WP_000291510.1 DUF1108 family protein -
  FORC12_RS06495 (FORC12_1166) - 1248484..1248786 (-) 303 WP_000165371.1 DUF2482 family protein -
  FORC12_RS06500 (FORC12_1167) - 1248881..1249042 (-) 162 WP_000048129.1 DUF1270 family protein -
  FORC12_RS06505 (FORC12_1168) - 1249039..1249362 (-) 324 WP_001120201.1 DUF771 domain-containing protein -
  FORC12_RS06510 (FORC12_1169) - 1249417..1249797 (+) 381 WP_000762519.1 DUF2513 domain-containing protein -
  FORC12_RS06515 (FORC12_1170) - 1249784..1249981 (-) 198 WP_001148862.1 hypothetical protein -
  FORC12_RS06520 (FORC12_1171) - 1249997..1250749 (-) 753 WP_001148605.1 phage antirepressor KilAC domain-containing protein -
  FORC12_RS06525 (FORC12_1172) - 1250800..1251129 (+) 330 WP_000128907.1 hypothetical protein -
  FORC12_RS06530 (FORC12_1173) - 1251118..1251333 (-) 216 WP_001025404.1 MW1434 family type I TA system toxin -
  FORC12_RS06535 (FORC12_1174) - 1251330..1251611 (-) 282 WP_000854074.1 helix-turn-helix transcriptional regulator -
  FORC12_RS06540 - 1251608..1251781 (-) 174 WP_001801500.1 hypothetical protein -
  FORC12_RS06545 (FORC12_1175) irvR 1251744..1252457 (+) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  FORC12_RS06550 (FORC12_1176) - 1252473..1253405 (+) 933 WP_000759682.1 exonuclease domain-containing protein -
  FORC12_RS06555 (FORC12_1177) - 1253411..1253752 (+) 342 WP_000591749.1 hypothetical protein -
  FORC12_RS06560 (FORC12_1178) - 1253956..1254138 (+) 183 WP_000705248.1 hypothetical protein -
  FORC12_RS06565 (FORC12_1179) - 1254238..1254702 (+) 465 WP_000825947.1 hypothetical protein -
  FORC12_RS06570 (FORC12_1180) - 1254761..1255798 (+) 1038 WP_000857191.1 site-specific integrase -
  FORC12_RS06575 (FORC12_1181) sph 1255849..1256679 (+) 831 Protein_1250 sphingomyelin phosphodiesterase -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=125567 FORC12_RS06545 WP_001031454.1 1251744..1252457(+) (irvR) [Staphylococcus aureus strain FORC_012 isolate human sputum]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=125567 FORC12_RS06545 WP_001031454.1 1251744..1252457(+) (irvR) [Staphylococcus aureus strain FORC_012 isolate human sputum]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401

Multiple sequence alignment