Detailed information NTG0124439

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GT95_RS09675
• Genome accession: NZ_CP008813
• Coordinates: 1858991..1861438 (-)
• Length: 815 a.a.
• NCBI ID: WP_000020288.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain C001
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1853991..1866438

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GT95_RS09650 (GT95_09350)	-	1854272..1855528 (+)	1257	WP_001285395.1	toxic anion resistance protein	-
GT95_RS09655 (GT95_09355)	hslO	1855668..1856543 (+)	876	WP_000357827.1	Hsp33 family molecular chaperone HslO	-
GT95_RS09660 (GT95_09360)	dusB	1856527..1857504 (+)	978	WP_000192735.1	tRNA dihydrouridine synthase DusB	-
GT95_RS09665 (GT95_09365)	-	1857625..1858266 (+)	642	WP_000909522.1	deoxynucleoside kinase	-
GT95_RS09670 (GT95_09370)	-	1858280..1858771 (+)	492	WP_000586896.1	GNAT family N-acetyltransferase	-
GT95_RS09675 (GT95_09375)	clpC	1858991..1861438 (-)	2448	WP_000020288.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GT95_RS09680 (GT95_09380)	-	1861435..1861899 (-)	465	WP_000985641.1	CtsR family transcriptional regulator	-
GT95_RS09685 (GT95_09385)	-	1862072..1862533 (+)	462	WP_001106578.1	small multi-drug export protein	-
GT95_RS09690 (GT95_09390)	tsf	1862693..1863733 (-)	1041	WP_000808080.1	translation elongation factor Ts	-
GT95_RS09695 (GT95_09395)	rpsB	1863827..1864597 (-)	771	WP_000268452.1	30S ribosomal protein S2	-
GT95_RS09700 (GT95_09400)	ahpC	1864874..1865434 (+)	561	WP_000060538.1	alkyl hydroperoxide reductase subunit C	-

Sequence

Protein

• Length: 815 a.a.
• Molecular weight: 90574.14 Da
• Isoelectric Point: 6.1486

>NTDB_id=124439 GT95_RS09675 WP_000020288.1 1858991..1861438(-) (clpC) [Streptococcus agalactiae strain C001]
MSHYSIKLQEVFRLAQFQAARYESHYLESWHLLLAMVLVHDSVAGLTFAEYESEVAIEEYEAATILALGRAPKEEITNYQ
FLEQSPALKKILKLAENISIVVGAEDVGTEHVLLAMLVNKDLLATRILELVGFRGQDDGESVRMVDLRKALERHAGFTKD
DIKAIYELRNPKKAKSGASFSDMMKPPSTAGDLADFTRDLSQMAVDGEIEPVIGRDKEISRMVQVLSRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGNIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFIDELHTIMGSGSG
IDSTLDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVLVEEPNLEDAYEILLGLKPAYEAFHNVTISDE
AVMTAVKVAHRYLTSKNLPDSAIDLLDEASATVQMMIKKNAPSLLTEVDQAILDDDMKSASKALKASHKGKKRKPIAVTE
DHIMATLSRLSGIPVEKLTQADSKKYLNLEKELHKRVIGQDDAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDISHDYTAMQKRIMEELKKAYRPEFINRIDEKVVFHS
LSQDNMREVVKIMVKPLILALKDKGMDLKFQPSALKHLAEDGYDIEMGARPLRRTIQTQVEDHLSELLLANQVKEGQVIK
IGVSKGKLKFDIAKS

Nucleotide

• Length: 2448 bp

>NTDB_id=124439 GT95_RS09675 WP_000020288.1 1858991..1861438(-) (clpC) [Streptococcus agalactiae strain C001]
ATGAGTCATTATTCCATAAAATTACAAGAAGTATTCAGATTGGCGCAATTTCAAGCAGCACGCTATGAAAGTCACTATTT
AGAAAGCTGGCATCTTCTTTTAGCAATGGTTTTAGTTCATGATTCAGTAGCTGGTTTGACATTTGCTGAATATGAGTCTG
AAGTTGCAATTGAAGAGTACGAAGCAGCAACAATTTTAGCTTTAGGTAGAGCACCGAAAGAAGAGATTACCAATTATCAA
TTTTTAGAGCAATCACCAGCTTTGAAAAAGATCTTAAAGTTAGCAGAAAATATTAGTATCGTAGTAGGAGCTGAAGATGT
GGGTACTGAACATGTCTTGCTTGCTATGTTGGTTAATAAAGATTTATTAGCCACACGTATCTTAGAATTAGTTGGCTTTA
GAGGTCAAGACGATGGTGAATCAGTTCGTATGGTTGATTTACGTAAGGCTCTAGAACGTCATGCCGGTTTTACAAAAGAT
GATATCAAAGCAATTTATGAATTACGTAATCCTAAAAAAGCAAAGTCGGGTGCTTCTTTTTCTGATATGATGAAACCACC
AAGTACTGCTGGTGATTTAGCTGATTTCACACGTGATTTATCACAGATGGCGGTTGATGGGGAAATTGAACCTGTTATTG
GGCGTGATAAAGAAATTTCACGTATGGTCCAAGTCTTAAGTCGTAAAACAAAGAATAATCCTGTCTTAGTTGGAGATGCG
GGTGTCGGTAAAACAGCTTTGGCGTACGGTCTAGCACAACGTATTGCTAATGGAAATATTCCTTATGAGCTTAGAGATAT
GCGTGTTCTAGAGTTAGATATGATGAGCGTTGTTGCTGGAACTCGTTTTCGTGGTGATTTTGAGGAACGTATGAATCAAA
TCATTGCAGATATTGAAGAAGACGGTCATATTATTCTTTTCATTGATGAACTGCATACTATTATGGGTTCTGGCTCTGGT
ATTGATAGCACACTTGATGCTGCTAATATTTTAAAACCAGCTTTGGCTCGAGGCACTTTACGCACTGTTGGAGCAACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAAGATGCTGCTTTATCCCGTCGCTTTGCAAAAGTTTTAGTAGAAGAACCAA
ATCTTGAAGACGCATATGAAATTCTACTTGGATTGAAGCCAGCGTATGAAGCCTTTCATAATGTTACTATTTCAGATGAA
GCAGTTATGACTGCTGTAAAAGTGGCTCATCGTTATTTGACAAGTAAGAATTTACCAGACTCAGCTATAGACTTACTTGA
TGAAGCTTCTGCCACTGTGCAAATGATGATTAAGAAAAATGCTCCTTCGCTTTTAACAGAAGTTGACCAAGCTATTTTAG
ATGATGATATGAAATCTGCTTCTAAAGCTCTAAAAGCAAGTCATAAGGGTAAAAAGCGTAAGCCTATTGCCGTAACAGAA
GATCATATTATGGCAACTCTCAGTCGTCTATCTGGTATTCCTGTTGAAAAATTGACACAAGCTGATAGTAAAAAATACCT
CAATTTAGAAAAAGAATTGCATAAACGTGTTATCGGTCAAGATGATGCAGTTACTGCCATTAGTCGTGCTATCCGTCGCA
ATCAATCTGGCATTCGTACTGGTAAGCGTCCTATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTTGGTAAGACAGAG
TTAGCAAAAGCCTTGGCAGAAGTGTTGTTTGATGATGAATCAGCCCTAATTCGTTTTGATATGTCGGAATATATGGAAAA
ATTCGCAGCTTCTCGCCTGAATGGGGCACCTCCAGGTTATGTTGGTTATGATGAAGGAGGAGAGTTGACTGAAAAAGTAC
GCAATAAACCATATTCAGTTTTACTTTTTGATGAAGTTGAAAAAGCTCATCCAGATATTTTTAATGTATTATTACAAGTG
CTTGATGATGGCGTTTTAACAGATAGTCGAGGACGAAAAGTTGACTTTTCAAATACTATAATCATTATGACTTCTAATTT
AGGAGCAACTGCATTACGTGACGATAAAACAGTTGGTTTTGGAGCTAAGGATATCAGCCATGATTATACTGCTATGCAAA
AACGTATTATGGAGGAGCTTAAAAAAGCTTATCGACCGGAGTTTATCAATCGTATTGATGAGAAAGTTGTATTCCATAGT
CTCAGTCAAGATAATATGCGTGAAGTTGTGAAAATTATGGTTAAACCTTTAATTTTAGCGCTTAAAGATAAAGGTATGGA
TCTGAAATTCCAGCCTTCAGCCTTGAAACACTTGGCAGAGGATGGCTATGATATAGAAATGGGTGCTCGTCCACTGCGTA
GAACTATTCAAACGCAAGTAGAGGATCATTTATCAGAACTACTATTGGCAAATCAAGTGAAAGAGGGGCAAGTAATTAAG
ATTGGCGTATCCAAAGGCAAATTGAAATTTGATATTGCAAAATCATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• AAA lid domain (AAA_lid_9) (375-470)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-367)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (105-132)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.478	99.632	0.762
clpC	Streptococcus thermophilus LMG 18311	72.883	100	0.729
clpC	Streptococcus thermophilus LMD-9	72.761	100	0.728
clpC	Streptococcus pneumoniae TIGR4	68.673	99.877	0.686
clpC	Streptococcus pneumoniae Rx1	68.673	99.877	0.686
clpC	Streptococcus pneumoniae D39	68.673	99.877	0.686
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.678	100	0.497
clpC	Bacillus subtilis subsp. subtilis str. 168	45.728	100	0.466
clpE	Streptococcus mutans UA159	46.238	78.282	0.362