Detailed information    

insolico Bioinformatically predicted

Overview

Name   rec2   Type   Machinery gene
Locus tag   C645_RS00320 Genome accession   NZ_CP008740
Coordinates   66166..68532 (-) Length   788 a.a.
NCBI ID   WP_005657747.1    Uniprot ID   A0A0H3PCV2
Organism   Haemophilus influenzae 2019     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 61166..73532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C645_RS00305 (C645_00310) kdsB 62456..63220 (-) 765 WP_005657753.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  C645_RS00310 (C645_00315) lpxK 63291..64289 (-) 999 WP_005657751.1 tetraacyldisaccharide 4'-kinase -
  C645_RS00315 (C645_00320) msbA 64362..66125 (-) 1764 WP_005657750.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  C645_RS00320 (C645_00325) rec2 66166..68532 (-) 2367 WP_005657747.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  C645_RS00325 (C645_00330) dksA 68792..69229 (+) 438 WP_005657744.1 RNA polymerase-binding protein DksA -
  C645_RS00330 (C645_00335) pcnB 69477..70835 (+) 1359 WP_005657742.1 polynucleotide adenylyltransferase PcnB -
  C645_RS00335 (C645_00340) folK 70844..71326 (+) 483 WP_005689907.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase -
  C645_RS00340 (C645_00345) tsaE 71402..71878 (+) 477 WP_005693857.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  C645_RS00345 (C645_00350) - 71886..73184 (+) 1299 WP_046067527.1 N-acetylmuramoyl-L-alanine amidase -

Sequence

Protein


Download         Length: 788 a.a.        Molecular weight: 89341.04 Da        Isoelectric Point: 10.0762

>NTDB_id=123943 C645_RS00320 WP_005657747.1 66166..68532(-) (rec2) [Haemophilus influenzae 2019]
MKLNLITLAVLLIVADLTLLFLPQPLLLPWQVALVIALVLIFLFIFLRRNFLVSLAFFVASLGYFHYSALSLLQQAQNIT
AQKQVVTFKIQEILHQQDYQTLIATATLANNLQEQRIFLNWKAKEVPQLSEIWQAEISLRPLSARLNFGGFDRQQWYFSK
GITVVGTVKSAVKIADVSSLRAEKLQQVKKQTEGLSLQGLLIALAFGERAWLDKTTWSIYQQTNTAHLIAISGLHIGLAM
GIGFCLVRVMQVFLPTRFIHPYFPLVFGVLLALIYAYLAGFSVPTFRAISALVFVLFIQIMRRHYSPIQLFTVVVGFLLF
CNPLMPLSVSFWLSCGAVGCLILWYRYVPFSLFQWKNRPFSPKVRWILSLFHLQFGLLLFFTPLQLFLFNGLSLSGFLAN
LMAVPIYSFLLVPLILFAVFTNGTMFSWQLANKLAEGITGLISVFQGNWLTVSFNLALFLTALCAGIFMLIIWRIYREPE
ASSSTWKIKRPRFFTLNLSKPLLKNDRINVLRCSFGIILLCFTILLFKQFSKPAWQVDTLDVGQGLATLIVKNGKGILYD
TGSSWRGGSMAELEILPYLQREGIVLEKLILSHDDNDHAGGASTILKAYPNVELITPSRKNYGENYRTFCTAGRDWHWQG
LHFQILSPHNVVTRADNPHSCVILVDDGKNSVLLTGDAEAKNEQIFARTLGKIDVLQVGHHGSKTSTSEYLLSQVRPDVA
IISSGRWNPWKFPHYSVMERLHRYKSAVENTAVSGQVRVNFFKDRLEIQQARTEFSPWYARVIGLSKE

Nucleotide


Download         Length: 2367 bp        

>NTDB_id=123943 C645_RS00320 WP_005657747.1 66166..68532(-) (rec2) [Haemophilus influenzae 2019]
ATGAAATTAAACTTAATAACTTTAGCTGTCTTGTTAATTGTCGCGGATTTAACGTTGTTATTTCTACCGCAACCGTTGCT
ATTGCCTTGGCAAGTTGCTCTCGTTATTGCGCTTGTTTTGATTTTTCTTTTTATTTTCTTGCGTAGAAATTTCTTAGTTA
GCCTTGCTTTTTTTGTTGCCTCTCTTGGCTATTTTCATTATTCGGCTTTGAGTTTATTACAACAAGCTCAAAATATTACC
GCTCAAAAGCAAGTGGTAACTTTTAAGATTCAAGAAATTTTGCACCAACAGGATTATCAAACGCTTATCGCCACAGCAAC
ATTGGCGAATAATTTGCAAGAACAACGAATTTTCTTAAATTGGAAAGCGAAAGAGGTGCCTCAATTATCGGAAATTTGGC
AAGCTGAAATTTCTTTACGTCCCCTTTCTGCACGATTAAATTTTGGTGGGTTTGATCGGCAACAATGGTATTTTTCAAAA
GGAATTACTGTTGTTGGAACGGTAAAAAGTGCGGTGAAAATTGCGGATGTTTCATCATTGCGTGCAGAAAAATTGCAACA
AGTAAAGAAGCAAACGGAAGGATTATCTCTACAAGGTTTATTGATTGCCTTAGCTTTTGGCGAACGGGCTTGGTTAGATA
AAACCACTTGGTCAATTTACCAACAAACCAATACCGCACATCTTATTGCTATTTCTGGCTTACATATTGGGTTGGCTATG
GGAATTGGATTTTGCTTGGTGCGTGTTATGCAAGTATTTTTACCCACCCGTTTTATTCATCCTTATTTTCCTTTAGTTTT
TGGTGTTTTATTGGCTTTAATTTATGCGTATTTGGCTGGTTTTAGCGTGCCAACTTTTCGTGCCATTTCAGCACTTGTTT
TCGTTTTATTTATTCAAATAATGAGGCGACATTATTCGCCCATTCAGCTTTTTACGGTGGTTGTCGGATTCTTGCTTTTC
TGCAATCCATTAATGCCGCTTTCGGTCAGTTTTTGGCTTTCTTGTGGGGCGGTTGGGTGTTTGATCCTCTGGTATCGTTA
TGTGCCTTTTTCTCTTTTTCAATGGAAAAATCGCCCCTTTTCACCAAAAGTGCGGTGGATTTTGAGTTTATTTCATTTGC
AATTTGGGTTATTGCTCTTTTTTACACCTTTGCAACTTTTTCTATTTAATGGCTTATCGTTGAGTGGATTTTTAGCCAAT
CTTATGGCGGTTCCAATTTATAGTTTTTTGCTTGTGCCATTAATTTTATTTGCCGTTTTTACTAACGGCACAATGTTTTC
TTGGCAACTAGCAAACAAGTTAGCCGAAGGAATTACTGGGTTAATTTCTGTTTTTCAAGGAAATTGGCTCACGGTTTCAT
TTAATTTAGCATTATTTTTAACCGCACTTTGTGCAGGAATTTTTATGTTAATTATTTGGCGTATTTATCGAGAACCAGAG
GCTTCATCATCAACTTGGAAAATTAAACGACCAAGATTTTTTACATTAAATCTCAGTAAACCTTTGCTAAAAAATGATCG
AATCAACGTTTTGCGATGTTCTTTCGGCATTATCTTACTGTGTTTTACGATTTTGTTGTTTAAACAATTTAGTAAGCCAG
CTTGGCAGGTAGATACTTTAGATGTGGGGCAGGGCTTGGCAACGCTGATTGTGAAAAATGGCAAAGGGATTCTTTATGAT
ACGGGTTCTTCTTGGCGAGGTGGAAGTATGGCTGAGTTGGAAATTTTGCCTTATTTACAAAGAGAAGGGATTGTTTTGGA
AAAATTGATTTTAAGCCACGACGATAACGATCACGCAGGTGGTGCTTCGACAATTTTAAAGGCGTATCCCAATGTGGAAT
TGATTACCCCTTCACGGAAAAACTATGGGGAAAATTACCGCACTTTTTGTACTGCTGGGCGTGATTGGCATTGGCAAGGG
TTGCATTTTCAAATACTTTCTCCTCACAATGTTGTGACACGAGCTGATAATCCCCATTCTTGTGTGATTTTAGTCGATGA
TGGAAAGAATAGTGTTTTGCTAACTGGCGATGCTGAAGCAAAAAATGAGCAAATTTTTGCCCGCACTTTAGGCAAAATCG
ATGTGTTGCAAGTGGGGCATCATGGGAGTAAAACATCGACAAGTGAATACTTGCTTTCTCAGGTTAGACCAGATGTAGCG
ATTATTTCTAGTGGGCGTTGGAATCCGTGGAAATTCCCTCATTATTCGGTTATGGAAAGGCTTCATCGCTATAAAAGTGC
GGTAGAAAATACCGCTGTTTCAGGGCAAGTGCGGGTAAATTTTTTTAAAGACCGATTAGAAATCCAACAAGCACGCACAG
AATTTTCCCCTTGGTATGCGCGTGTAATTGGATTATCAAAGGAATAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(204-473)

Domain of unknown function (DUF4131) (DUF4131)

(28-171)

Metallo-beta-lactamase superfamily (Lactamase_B)

(541-725)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3PCV2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rec2 Haemophilus influenzae Rd KW20

96.447

100

0.964

Multiple sequence alignment