Detailed information    

experimental Experimentally validated

Overview

Name   Cj1211   Type   Unclear
Locus tag   Cj1211 Genome accession   NC_002163
Coordinates   1139621..1140880 (+) Length   419 a.a.
NCBI ID   YP_002344602.1    Uniprot ID   -
Organism   Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819     
Function   require for natural transformation   
Unclear

Function

Insertional mutagenesis of Cj1211, a Helicobacter pylori ComH3 homolog, abolished natural transformation in C. jejuni. A mutation of Cj1211 or the addition of DNase I in culture media completely inhibited the formation of progenies that were resistant to both antibiotics, indicating that the horizontal transfer of the resistance determinants is mediated by natural transformation.


Genomic Context

Location: 1134621..1145880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Cj1206c ftsY 1135449..1136315 (-) 867 YP_002344597.1 signal recognition particle protein -
  Cj1207c - 1136315..1136872 (-) 558 YP_002344598.1 lipoprotein thiredoxin -
  Cj1208 - 1136955..1137581 (+) 627 YP_002344599.1 5-formyltetrahydrofolate cyclo-ligase -
  Cj1209 - 1137502..1139055 (+) 1554 YP_002344600.1 ribonuclease Y -
  Cj1210 - 1139064..1139621 (+) 558 YP_002344601.1 integral membrane protein -
  Cj1211 Cj1211 1139621..1140880 (+) 1260 YP_002344602.1 competence family protein Unclear
  Cj1212c rbn 1140824..1141630 (-) 807 YP_002344603.1 ribonuclease BN -
  Cj1213c glcD 1141634..1143016 (-) 1383 YP_002344604.1 glycolate oxidase subunit D -
  Cj1214c - 1143019..1143744 (-) 726 YP_002344605.1 exporting protein -
  Cj1215 - 1143866..1145026 (+) 1161 YP_002344606.1 peptidase M23 family protein -
  Cj1216c - 1145023..1145226 (-) 204 YP_002344607.1 hypothetical protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 50159.87 Da        Isoelectric Point: 9.6115

>NTDB_id=1238 Cj1211 YP_002344602.1 1139621..1140880(+) (Cj1211) [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]
MSLWNSFSYSFKEFHYLFFSVVVIFIFNILLEYNNFLNFKNQKHYLIDNALLTHQYIKYNKKNKKYWVLKLQTENFTFYT
TSFKDLNLSKNQFLSLRIITHNINFKDYLSKSFYAPSYDFEKLKEKEYNPIISYFLNQHTNEKIKEFYGALFFALPISLE
LRNDVNYYGIAHLIAISGYHIGLLFSLIFFILAPIYSFFQKRYFPYRNLRLDLSILIFALLLAYACLIGFVPSFVRSLIM
AFWVFYLLCKNIKIINFVTLFCSILLCISLYPRLLFSIGFLFSILGVFYIFLYMHHFANKFNNLINIILLNIWTFFAMVL
PVLYFFPLISYQQILGIILSGIFVIFYPLVLFLHLINYGDLLNFILDEFFKFKIYGTNIHIPFWIFISYLIASLISVRFK
YLAFLCIFANFIPFIMIVI

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1238 Cj1211 YP_002344602.1 1139621..1140880(+) (Cj1211) [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]
ATGTCTCTATGGAATTCTTTTTCTTACTCTTTTAAAGAATTTCATTATTTATTTTTCTCTGTTGTTGTTATTTTTATTTT
TAATATCCTTTTAGAATATAATAATTTTTTAAACTTTAAAAACCAAAAACATTACCTTATAGACAACGCTCTATTAACGC
ACCAATATATAAAATATAATAAAAAAAATAAAAAATACTGGGTTTTAAAGTTACAAACTGAAAACTTCACTTTTTATACT
ACAAGTTTTAAGGATTTAAATTTAAGCAAGAATCAATTTTTGAGCCTTAGAATTATCACCCATAATATTAACTTTAAAGA
CTATCTGAGTAAAAGTTTTTACGCACCTTCTTATGATTTTGAAAAATTAAAAGAAAAAGAATACAATCCCATTATATCTT
ACTTCTTAAATCAACATACAAATGAAAAGATTAAAGAATTTTATGGTGCTTTATTTTTTGCACTGCCCATATCTTTAGAG
CTTAGAAACGATGTAAATTACTACGGTATAGCACACCTTATAGCAATTAGCGGTTATCACATAGGCTTACTTTTTAGTTT
AATTTTCTTTATTTTAGCTCCAATTTATAGTTTTTTCCAAAAAAGATATTTTCCTTATAGAAATTTACGTTTAGATTTAA
GTATTTTAATTTTTGCACTACTTTTAGCTTATGCTTGTTTAATAGGATTTGTCCCTTCTTTTGTGCGCTCCTTGATTATG
GCTTTTTGGGTTTTTTATCTATTGTGTAAAAATATAAAAATCATTAATTTCGTTACGCTTTTTTGTAGTATTTTATTGTG
CATTTCTCTTTACCCTAGACTTTTATTTAGTATTGGATTTTTATTTTCTATTTTAGGTGTTTTTTATATTTTTTTATATA
TGCATCATTTTGCAAATAAATTTAATAATCTTATAAATATTATTTTGCTTAATATTTGGACTTTTTTTGCTATGGTTTTA
CCTGTGCTTTATTTTTTTCCACTTATAAGCTACCAACAAATTTTAGGTATTATTTTGAGTGGAATTTTTGTAATATTTTA
TCCTTTAGTATTATTTTTGCATCTTATAAACTATGGAGATTTGCTCAATTTTATCTTAGATGAATTTTTTAAATTTAAAA
TTTATGGAACTAATATCCATATCCCATTTTGGATTTTTATAAGTTATCTTATTGCTTCTTTAATCTCTGTGCGATTTAAA
TATCTAGCTTTTCTTTGTATTTTTGCGAATTTTATTCCCTTCATTATGATTGTGATTTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(158-358)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value

References

[1] Byeonghwa Jeon et al. (2008) Role of Cj1211 in natural transformation and transfer of antibiotic resistance determinants in Campylobacter jejuni. Antimicrobial Agents And Chemotherapy 52(8):2699-708. [PMID: 18505858]