Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   CAQ16704_RS02590 Genome accession   NZ_CP007769
Coordinates   490884..492677 (-) Length   597 a.a.
NCBI ID   WP_039666756.1    Uniprot ID   A0A0A8GWJ0
Organism   Campylobacter sp. RM16704     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 485884..497677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAQ16704_RS02565 (CAQ16704_0513) dnaJ 486155..487276 (-) 1122 WP_039666751.1 molecular chaperone DnaJ -
  CAQ16704_RS02570 (CAQ16704_0514) - 487395..488066 (+) 672 WP_039666752.1 response regulator transcription factor -
  CAQ16704_RS02575 (CAQ16704_0515) - 488063..489298 (+) 1236 WP_039666753.1 ArsS family sensor histidine kinase -
  CAQ16704_RS02580 (CAQ16704_0516) recR 489300..489872 (+) 573 WP_039666754.1 recombination mediator RecR -
  CAQ16704_RS02585 (CAQ16704_0517) - 489859..490887 (-) 1029 WP_039666755.1 hypothetical protein -
  CAQ16704_RS02590 (CAQ16704_0518) uvrC 490884..492677 (-) 1794 WP_039666756.1 excinuclease ABC subunit UvrC Machinery gene
  CAQ16704_RS02595 (CAQ16704_0519) - 492664..493116 (-) 453 WP_052244975.1 hypothetical protein -
  CAQ16704_RS02605 (CAQ16704_0520) nhaD 493260..494615 (+) 1356 WP_039666759.1 sodium:proton antiporter NhaD -
  CAQ16704_RS02610 (CAQ16704_0521) guaA 494625..496160 (+) 1536 WP_039666760.1 glutamine-hydrolyzing GMP synthase -
  CAQ16704_RS02615 (CAQ16704_0522) - 496161..496712 (-) 552 WP_039666761.1 methyltransferase domain-containing protein -

Sequence

Protein


Download         Length: 597 a.a.        Molecular weight: 69992.48 Da        Isoelectric Point: 9.9288

>NTDB_id=123167 CAQ16704_RS02590 WP_039666756.1 490884..492677(-) (uvrC) [Campylobacter sp. RM16704]
MLENELKTLPNLPGIYQYFDIQGRLLYVGKAKNLKNRVKSYFNFAPKLCPNPNNSLRIQKMISQTHHLEFITTNSEADAL
ILENSFIKQLHPKYNILLRDDKTYPYIYIDFSDDFPRFEITRKIIKKNKIKYFGPFFKGAKELINALYLTFPLRQKKTCK
ELCLFYQIKRCKGPCKEKISKQEYEKIIQKATQALLNPLSLVKNLESKMLEYAKNENYEDAAIIRDQIKTIQELSVKIQI
DLAKLEDFDIFAIYCEENILSMVRFVVNNGKVISSNYKILVLKNHNEFDKNAIYKQYILENYTKEAPINSNHIYTYEEFE
DMKLLQDLLSKRFSKKFYIKTPKLREKKDLCSLALENAKINIQKHLKNEHYLILKEIKEYFKLQNFPNRIEIFDNSHMQG
IANVGGLVVFKDGGFDKKSYRHYHLKHKNDYEQMLEILSKRALSFDKNPPPDLWIIDGGSALLKLANDIIKSSGANVDIL
AISKEKIDAKAHRAKGSAKDKLYTLEGKIQLLPEDKKLQFFQKLRDEAHRFAISFHQRTKRKQDLQSSKLIQLGISQGYI
KKFLDYYGSFDKILNADFNELKLLSNTKIAKLIKENL

Nucleotide


Download         Length: 1794 bp        

>NTDB_id=123167 CAQ16704_RS02590 WP_039666756.1 490884..492677(-) (uvrC) [Campylobacter sp. RM16704]
ATGCTAGAAAATGAACTTAAAACTTTACCCAATTTACCAGGTATATATCAGTATTTTGATATTCAAGGTAGGCTTTTATA
TGTAGGAAAGGCTAAAAATTTAAAAAATAGAGTAAAAAGTTATTTTAATTTTGCCCCAAAGCTTTGTCCTAATCCAAATA
ATAGTTTAAGAATTCAAAAAATGATTAGCCAAACTCATCATTTAGAATTCATCACAACAAATAGTGAAGCTGATGCTTTA
ATTTTGGAAAATTCTTTCATAAAACAACTTCATCCAAAATATAACATACTATTAAGAGATGATAAAACTTATCCTTATAT
TTATATAGATTTTAGTGATGACTTTCCAAGATTTGAAATTACAAGAAAAATTATTAAAAAAAACAAAATCAAATATTTTG
GACCTTTTTTTAAAGGAGCAAAAGAACTTATAAATGCTTTATATCTAACCTTTCCATTGAGACAAAAAAAAACTTGTAAA
GAACTTTGTCTGTTTTATCAAATAAAACGTTGTAAAGGACCTTGTAAAGAAAAAATTTCCAAGCAAGAATATGAAAAAAT
CATACAAAAAGCAACACAAGCTCTTTTAAACCCTTTATCTTTGGTAAAAAATTTAGAAAGTAAAATGCTTGAATATGCAA
AAAATGAAAACTATGAAGATGCTGCTATTATTAGGGATCAAATTAAAACCATTCAAGAATTAAGTGTAAAAATACAAATT
GATCTTGCTAAATTAGAAGATTTTGATATTTTTGCTATATATTGCGAAGAAAACATACTTTCTATGGTACGTTTTGTAGT
AAATAATGGAAAAGTAATTAGCTCAAATTATAAAATTTTAGTTTTGAAAAATCACAATGAATTTGATAAAAATGCAATCT
ATAAACAATATATTTTAGAAAATTACACCAAAGAAGCACCTATAAATTCAAATCATATTTATACATATGAAGAATTTGAA
GATATGAAACTCTTACAAGATTTACTTAGCAAAAGGTTTTCTAAAAAATTTTATATCAAAACACCAAAACTTAGAGAAAA
AAAAGATCTATGTAGTTTAGCTCTAGAAAATGCAAAAATTAATATACAAAAACATTTAAAAAATGAACATTATTTAATCT
TAAAAGAAATCAAAGAATATTTTAAATTGCAAAATTTTCCTAATCGTATAGAGATTTTTGATAATTCTCATATGCAAGGA
ATTGCAAATGTTGGTGGATTGGTGGTATTTAAAGATGGAGGTTTTGATAAAAAATCTTATAGACACTATCATTTAAAACA
TAAAAATGATTACGAACAAATGCTTGAAATTCTTAGCAAAAGAGCTTTGTCCTTTGACAAAAACCCACCACCTGATTTAT
GGATTATTGATGGAGGGAGTGCGTTATTAAAACTAGCAAATGATATTATAAAAAGTTCAGGGGCAAATGTAGATATATTA
GCTATATCTAAAGAAAAAATTGATGCAAAAGCCCATAGAGCAAAAGGGAGTGCTAAAGATAAACTTTATACATTAGAAGG
TAAAATCCAACTTTTACCTGAAGACAAAAAACTACAATTTTTTCAAAAATTACGTGATGAAGCACACCGCTTTGCTATTA
GTTTTCATCAAAGAACAAAAAGAAAACAAGATTTACAAAGTTCAAAATTGATACAACTTGGGATTTCTCAAGGATATATT
AAAAAATTTTTAGATTATTATGGTAGTTTTGATAAAATCTTAAATGCTGATTTTAATGAATTAAAACTACTTTCTAACAC
AAAAATTGCAAAATTAATTAAGGAAAATTTATGA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(13-95)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(379-533)

UvrB/uvrC motif (UVR)

(201-233)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0A8GWJ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

49.231

97.99

0.482

Multiple sequence alignment