Detailed information NTG0122743

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EX97_RS14250
• Genome accession: NZ_CP007690
• Coordinates: 2769216..2770103 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2764216..2775103

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EX97_RS14215	-	2764235..2764327 (+)	93	WP_010956583.1	hypothetical protein	-
EX97_RS14220 (EX97_13395)	-	2764435..2764932 (-)	498	WP_001065268.1	glutathione peroxidase	-
EX97_RS14225	-	2764942..2765202 (-)	261	WP_001789910.1	hypothetical protein	-
EX97_RS14230	-	2765584..2765697 (-)	114	WP_001791776.1	hypothetical protein	-
EX97_RS14240 (EX97_13400)	-	2766356..2768356 (-)	2001	WP_000776751.1	ABC transporter permease	-
EX97_RS14245 (EX97_13405)	-	2768353..2769108 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EX97_RS14250 (EX97_13410)	braS	2769216..2770103 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EX97_RS14255 (EX97_13415)	braR	2770114..2770779 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EX97_RS14260 (EX97_13420)	-	2770805..2771005 (-)	201	WP_000604728.1	hypothetical protein	-
EX97_RS14270 (EX97_13425)	-	2771203..2772627 (+)	1425	WP_038410201.1	alkaline phosphatase	-
EX97_RS15895	-	2772687..2772788 (-)	102	WP_000731972.1	SE2200 family small protein	-
EX97_RS14275 (EX97_13435)	-	2772910..2773365 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EX97_RS14280 (EX97_13440)	-	2773610..2774371 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=122743 EX97_RS14250 WP_000143419.1 2769216..2770103(-) (braS) [Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=122743 EX97_RS14250 WP_000143419.1 2769216..2770103(-) (braS) [Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997