Detailed information NTG0122738

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EX97_RS10215
• Genome accession: NZ_CP007690
• Coordinates: 2026902..2027945 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2021902..2032945

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EX97_RS10185 (EX97_09710)	-	2022320..2023576 (-)	1257	WP_001795438.1	aminopeptidase	-
EX97_RS10190 (EX97_09715)	-	2023579..2023779 (-)	201	WP_000180461.1	DUF1128 family protein	-
EX97_RS10195 (EX97_09720)	-	2023926..2024390 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
EX97_RS10200 (EX97_09725)	-	2024397..2024672 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
EX97_RS10205 (EX97_09730)	-	2024950..2026167 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
EX97_RS10210 (EX97_09735)	vraR	2026283..2026912 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
EX97_RS10215 (EX97_09740)	vraS	2026902..2027945 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
EX97_RS10220 (EX97_09745)	liaF	2027942..2028643 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
EX97_RS10225 (EX97_09750)	-	2028658..2029044 (-)	387	WP_001110179.1	hypothetical protein	-
EX97_RS10230 (EX97_09755)	map	2029261..2030019 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
EX97_RS10240 (EX97_09760)	-	2030547..2031533 (+)	987	WP_000999713.1	FUSC family protein	-
EX97_RS10245 (EX97_09765)	-	2032023..2032436 (-)	414	WP_001549145.1	hypothetical protein	-
EX97_RS10250	-	2032465..2032575 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=122738 EX97_RS10215 WP_001017131.1 2026902..2027945(-) (vraS) [Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=122738 EX97_RS10215 WP_001017131.1 2026902..2027945(-) (vraS) [Staphylococcus aureus strain UA-S391_USA300 isolate abscess/wound isolate]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1