Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   ER12_RS04925 Genome accession   NZ_CP007676
Coordinates   1003288..1003857 (-) Length   189 a.a.
NCBI ID   WP_000287265.1    Uniprot ID   A0A7U7EXU5
Organism   Staphylococcus aureus strain HUV05     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 998288..1008857
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ER12_RS04905 (ER12_004665) - 999793..1001151 (+) 1359 WP_048520576.1 TrkH family potassium uptake protein -
  ER12_RS04910 (ER12_004670) - 1001290..1002801 (+) 1512 WP_000414177.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
  ER12_RS04925 (ER12_004685) comK/comK1 1003288..1003857 (-) 570 WP_000287265.1 competence protein ComK Regulator
  ER12_RS04930 (ER12_004690) - 1004067..1004285 (+) 219 WP_000876826.1 IDEAL domain-containing protein -
  ER12_RS04935 (ER12_004695) - 1004366..1005352 (-) 987 WP_000668820.1 lipoate--protein ligase -
  ER12_RS04940 - 1005551..1005727 (+) 177 WP_000214898.1 YkvS family protein -
  ER12_RS04945 (ER12_004705) - 1005742..1006344 (+) 603 WP_001033867.1 CPBP family glutamic-type intramembrane protease -
  ER12_RS15970 - 1006660..1006722 (+) 63 WP_228764722.1 hypothetical protein -
  ER12_RS04955 - 1007261..1007362 (+) 102 WP_001790623.1 hypothetical protein -
  ER12_RS15175 - 1007384..1007644 (+) 261 WP_130137088.1 lactococcin 972 family bacteriocin -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 22601.83 Da        Isoelectric Point: 9.6091

>NTDB_id=122422 ER12_RS04925 WP_000287265.1 1003288..1003857(-) (comK/comK1) [Staphylococcus aureus strain HUV05]
MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFKVQKIIERSCKFYGNTYLGKKAETNRITGISSKPPIL
LTPLFPTYFFPTHSDRQNENIWLNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
KNPDQPIDYNKATLNVFEALTRYSLFEDK

Nucleotide


Download         Length: 570 bp        

>NTDB_id=122422 ER12_RS04925 WP_000287265.1 1003288..1003857(-) (comK/comK1) [Staphylococcus aureus strain HUV05]
ATGTATTCTCAAAATATTTATGTGATACGCAAAGGAGACATGGTTATTCGACCAGCATTTGATGATGACGATCAAAGAAA
CGGTAGTGAAATAATTCGGTTTGACAAAACGCGTATTCAAAATCCTTTTAAAGTCCAGAAAATCATTGAACGCTCTTGCA
AATTTTATGGTAATACTTATCTTGGCAAGAAAGCAGAGACAAACCGCATTACTGGCATTTCTAGTAAACCACCTATTTTA
CTAACACCATTATTTCCAACTTATTTTTTCCCAACACATTCTGACAGACAAAATGAAAATATTTGGTTAAATATGCATTA
TATCGAAAGTATTAAAGAATTAAAAAATCGTAAATGTAAAGTGACATTTATTAATAATGAATCAATCATTCTTCATGTTT
CATACCACAGTTTATGGCATCAATATAACAATTCCATTTTTTACTATTACATGGTAGATAAACAATCTCGCATGATATCA
AAAAATCCCGACCAACCAATAGATTATAATAAAGCCACATTGAATGTGTTTGAAGCATTGACACGCTATTCTTTATTTGA
AGATAAATAA

Domains

Predicted by InterproScan.

ComK protein (ComK)

(5-156)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

100

100

1
  comK/comK1 Staphylococcus aureus N315

100

100

1

Multiple sequence alignment