Detailed information NTG0122367

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EQ80_RS14065
• Genome accession: NZ_CP007672
• Coordinates: 2736612..2737499 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CA12
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2731612..2742499

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQ80_RS14030	-	2731631..2731723 (+)	93	WP_010956583.1	hypothetical protein	-
EQ80_RS14035 (EQ80_013185)	-	2731831..2732328 (-)	498	WP_001065268.1	glutathione peroxidase	-
EQ80_RS14040	-	2732338..2732598 (-)	261	WP_001789910.1	hypothetical protein	-
EQ80_RS14045	-	2732980..2733093 (-)	114	WP_001791776.1	hypothetical protein	-
EQ80_RS14055 (EQ80_013190)	-	2733752..2735752 (-)	2001	WP_000776751.1	ABC transporter permease	-
EQ80_RS14060 (EQ80_013195)	-	2735749..2736504 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EQ80_RS14065 (EQ80_013200)	braS	2736612..2737499 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EQ80_RS14070 (EQ80_013205)	braR	2737510..2738175 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EQ80_RS14075 (EQ80_013210)	-	2738201..2738401 (-)	201	WP_000604728.1	hypothetical protein	-
EQ80_RS14085 (EQ80_013215)	-	2738599..2740023 (+)	1425	Protein_2669	alkaline phosphatase	-
EQ80_RS15825	-	2740083..2740184 (-)	102	WP_000731972.1	SE2200 family small protein	-
EQ80_RS14090 (EQ80_013225)	-	2740306..2740761 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EQ80_RS14095 (EQ80_013230)	-	2741006..2741767 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=122367 EQ80_RS14065 WP_000143419.1 2736612..2737499(-) (braS) [Staphylococcus aureus strain CA12]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=122367 EQ80_RS14065 WP_000143419.1 2736612..2737499(-) (braS) [Staphylococcus aureus strain CA12]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997