Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   M0579_RS07145 Genome accession   NZ_CP007668
Coordinates   1424756..1427851 (-) Length   1031 a.a.
NCBI ID   WP_002224080.1    Uniprot ID   -
Organism   Neisseria meningitidis M0579     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1419756..1432851
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M0579_RS07120 (M0579_01317) - 1420854..1421243 (-) 390 WP_002224081.1 endonuclease domain-containing protein -
  M0579_RS07130 (M0579_01318) - 1421802..1421939 (-) 138 WP_002214606.1 VOC family protein -
  M0579_RS07135 (M0579_01319) carA 1421985..1423118 (-) 1134 WP_002217954.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  M0579_RS07145 (M0579_01320) pilC 1424756..1427851 (-) 3096 WP_002224080.1 PilC family type IV pilus tip adhesin Machinery gene
  M0579_RS07160 (M0579_01322) apbC 1429108..1430187 (-) 1080 WP_025458580.1 iron-sulfur cluster carrier protein ApbC -
  M0579_RS07170 (M0579_01324) - 1430552..1431061 (+) 510 WP_002224078.1 protein disulfide oxidoreductase -
  M0579_RS07180 (M0579_01325) nadR 1431404..1431844 (+) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  M0579_RS07185 (M0579_01326) hpaC 1431959..1432459 (+) 501 WP_002224077.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -

Sequence

Protein


Download         Length: 1031 a.a.        Molecular weight: 113113.04 Da        Isoelectric Point: 9.7512

>NTDB_id=122240 M0579_RS07145 WP_002224080.1 1424756..1427851(-) (pilC) [Neisseria meningitidis M0579]
MNKTLKRQVFRHTALYAAILMFSHTGGGAQAETHNYAIVMNEQNQLKVKQKGLYSTLREKDRERKFIYNKSWQGGGSVFF
DNTDTLVSRQSGTAVFGTATYLPPYGKVSGFDANALKERNNAVDWIHTTRAGLAGYAYTNVICRSHQCPQLVYKTRFSFD
NPDLAKRGGGLDRHTEPSRDNSLIYKLKDHPWLGVSFNLGSENTVKNSQSSSRLISSFSEDNNNQTIVSTTENHPISLGD
RQREHTAVAYYLNAKLHLLDKKGIKDITGKTVRLGVLKPSIDVKTQRTGLGGLLGFHAKWDIKDTGQIPVELGLPQIKAG
RCINKPNPNPKAQALSPALTAPALWFGPVQNGKVQMYSASVSTYPDSSSSQIFLQNLSRKDDTSKPGRYSLKPLSTSEIK
SKEPTFTGRQTVIRLDGGVQQIKLQGNEVTSFNVNNGNNTFGIVKDLGVDPDASEWKKVLLPWTVRASNDDNQFKTINQQ
LNQQKIQYSQRYRIRDNGNRDLGDIVNSPIVAVGEYLATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRQYFDNDTS
ALKDSTLAKELRTFAEKGYVGDRYGVDGGFVLRQVNNLNGQDRVFMFGAMGFGGRGAYALDLSKIDSNNPTAVSLFDVKN
DDKNNNGVKLGYTVGTPQIGKTHNGKYAAFLASGYATKKIDDQTNKTALYVYDLESNNGTPIATINVPDGKGGLSSPTLV
DKDLDGTVDIAYAGDRGGNMYRFDLSSQDPKQWSARAIFKGDKPITSAPAISQLKDKRVVIFGTGSDLSEEDVDKKDEQY
IYGIFDDDTATTGSVNFSGSGGGLLEQHLTQEDKTLFLTDYKRSDGSGNKGWIVKLKDGQRVTVKPTVVLRTAFVTIRKY
TDNGCGAETAILGINTADGGKLTKKSARPIVPEANQAVAQYSGHKQTAKGKSIPIGCMEKDNGIVCPNGYVYDKPVNVRY
LDEKKTDGFSTTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 3096 bp        

>NTDB_id=122240 M0579_RS07145 WP_002224080.1 1424756..1427851(-) (pilC) [Neisseria meningitidis M0579]
ATGAATAAAACTTTAAAAAGGCAGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGGGG
GGGGGCGCAGGCGGAAACCCATAACTACGCTATTGTCATGAACGAACAAAATCAGCTGAAGGTAAAGCAGAAGGGTTTAT
ATTCAACCTTAAGGGAAAAAGACAGGGAACGCAAATTTATCTATAATAAAAGCTGGCAGGGTGGAGGCTCTGTCTTTTTC
GACAATACCGATACCCTTGTTTCCCGACAAAGCGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGGCAA
GGTTTCCGGTTTTGATGCCAACGCTCTGAAAGAGCGCAACAATGCCGTCGATTGGATTCATACCACCCGGGCCGGGCTGG
CAGGCTACGCCTACACCAACGTCATATGCAGAAGCCACCAATGCCCCCAACTTGTCTATAAAACCCGATTTTCCTTCGAT
AATCCCGACTTGGCAAAAAGAGGAGGCGGGCTGGATAGGCACACAGAGCCAAGCCGCGACAATTCGCTCATTTACAAATT
GAAGGATCATCCATGGTTGGGCGTATCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATAGCCAATCATCCAGCAGAT
TGATATCTTCTTTTAGTGAAGACAATAATAATCAAACCATCGTCTCTACGACAGAAAACCACCCTATTTCCCTTGGCGAC
AGGCAGCGCGAACATACCGCCGTGGCCTATTATCTGAACGCCAAACTGCACCTGCTGGATAAAAAAGGGATTAAAGATAT
CACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGACACAAAGGACGGGGCTTGGCGGCTTGC
TAGGTTTTCATGCTAAGTGGGACATTAAAGATACCGGGCAGATTCCGGTCGAGCTCGGCCTGCCGCAAATCAAAGCAGGC
CGCTGCATCAACAAACCGAACCCCAATCCCAAAGCCCAAGCCCTTTCGCCGGCACTGACTGCCCCCGCGCTGTGGTTCGG
ACCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCCACCTACCCCGACAGTTCGAGCAGCCAAATTTTCC
TGCAAAACCTTTCCCGCAAGGATGACACAAGCAAACCGGGCCGCTATTCCCTCAAACCCTTGAGTACGTCGGAGATTAAA
AGTAAAGAGCCGACTTTCACAGGGCGGCAAACCGTCATCCGATTGGATGGCGGCGTACAGCAGATTAAACTTCAAGGCAA
TGAGGTCACTAGTTTTAATGTAAACAACGGCAACAACACTTTCGGCATTGTTAAGGACTTGGGCGTCGATCCTGATGCCA
GCGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTCCAATGATGACAATCAATTTAAAACAATTAACCAACAA
CTTAACCAACAAAAAATCCAATACAGCCAAAGATACCGCATCCGCGACAACGGCAATCGCGATTTGGGCGACATCGTCAA
CAGCCCCATCGTGGCGGTCGGCGAGTATTTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAACAAAGCGGCG
GGGACAAGCGCAGCTACAATCTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACTTCC
GCTCTCAAAGACTCCACCCTCGCCAAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGA
CGGCGGCTTTGTCTTGCGCCAAGTTAACAACTTAAATGGGCAAGACCGCGTGTTTATGTTCGGCGCGATGGGCTTTGGCG
GCAGAGGCGCATACGCCTTGGATTTAAGCAAAATCGACAGCAATAACCCGACCGCCGTTTCCCTGTTTGATGTCAAAAAT
GACGATAAAAACAATAATGGCGTGAAATTAGGCTACACCGTCGGCACGCCGCAAATCGGCAAAACCCACAACGGCAAATA
CGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAAAAATTGACGACCAAACAAATAAAACCGCGCTGTATGTGTATGATT
TGGAAAGCAACAACGGTACGCCGATTGCAACAATCAACGTACCCGACGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTG
GATAAAGATTTGGACGGCACGGTCGATATCGCCTATGCCGGCGATCGCGGCGGGAATATGTACCGCTTTGATTTGAGCAG
TCAAGATCCTAAACAATGGTCTGCACGCGCCATTTTTAAAGGCGACAAACCGATTACTTCCGCGCCCGCCATTTCCCAAC
TGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGCGATTTGAGTGAGGAGGATGTGGACAAAAAGGACGAACAATAT
ATTTACGGTATCTTCGACGACGATACGGCGACGACGGGTTCTGTAAACTTCAGCGGTTCGGGAGGCGGGCTGCTCGAGCA
ACACCTTACTCAGGAAGATAAAACCTTATTCCTGACCGATTACAAGCGATCCGACGGATCGGGCAATAAGGGCTGGATAG
TGAAATTGAAGGACGGACAACGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTAACCATCCGCAAATAT
ACTGACAACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGC
GCGCCCGATTGTGCCGGAAGCCAATCAGGCTGTCGCGCAATATTCCGGCCATAAGCAAACCGCCAAAGGCAAATCCATCC
CTATAGGTTGTATGGAAAAAGACAATGGAATCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGTTAT
CTGGATGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCGATGCGGGCGGCAGCGGAACATTCAAAGAGGGTAA
AAAACCCGCCCGCAATAACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGACA
TTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGTCTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(502-839)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

78.086

100

0.791

Multiple sequence alignment