Detailed information
Bioinformatically predicted
Overview
| Name | pilH | Type | Machinery gene |
| Locus tag | B6116_RS06525 | Genome accession | NZ_CP007667 |
| Coordinates | 1258368..1259033 (+) | Length | 221 a.a. |
| NCBI ID | WP_047957332.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis strain B6116/77 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 1256653..1318354 | 1258368..1259033 | within | 0 |
Gene organization within MGE regions
Location: 1256653..1318354
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| B6116_RS06520 (B6116_01227) | dnaB | 1256653..1258059 (+) | 1407 | WP_002227431.1 | replicative DNA helicase | - |
| B6116_RS06525 (B6116_01228) | pilH | 1258368..1259033 (+) | 666 | WP_047957332.1 | GspH/FimT family pseudopilin | Machinery gene |
| B6116_RS06530 (B6116_01229) | pilV | 1259066..1259677 (+) | 612 | WP_047957366.1 | type IV pilus modification protein PilV | Machinery gene |
| B6116_RS06535 (B6116_01230) | pilJ | 1259674..1260654 (+) | 981 | WP_047957333.1 | PilW family protein | Machinery gene |
| B6116_RS06540 (B6116_01231) | pilK | 1260633..1261226 (+) | 594 | WP_047957334.1 | pilus assembly PilX family protein | Machinery gene |
| B6116_RS06545 (B6116_01232) | pilX | 1261231..1261704 (+) | 474 | WP_193376947.1 | PilX family type IV pilin | Machinery gene |
| B6116_RS06555 (B6116_01233) | - | 1264804..1265232 (-) | 429 | Protein_1237 | AzlC family ABC transporter permease | - |
| B6116_RS06560 (B6116_01234) | dut | 1265375..1265827 (+) | 453 | WP_002226436.1 | dUTP diphosphatase | - |
| B6116_RS06565 (B6116_01235) | dapC | 1265903..1267090 (+) | 1188 | WP_002222650.1 | succinyldiaminopimelate transaminase | - |
| B6116_RS15435 | - | 1267178..1267303 (+) | 126 | Protein_1240 | IS5/IS1182 family transposase | - |
| B6116_RS06570 (B6116_01236) | yaaA | 1267352..1268131 (+) | 780 | WP_002220681.1 | peroxide stress protein YaaA | - |
| B6116_RS06585 (B6116_01239) | - | 1268663..1269859 (+) | 1197 | WP_002238460.1 | tyrosine-type recombinase/integrase | - |
| B6116_RS06590 (B6116_01240) | - | 1270014..1270394 (+) | 381 | WP_002220683.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| B6116_RS06605 (B6116_01241) | - | 1270830..1271309 (+) | 480 | WP_002244521.1 | DUF4760 domain-containing protein | - |
| B6116_RS06610 (B6116_01242) | - | 1272177..1273094 (+) | 918 | WP_002220686.1 | KilA-N domain-containing protein | - |
| B6116_RS06615 (B6116_01243) | - | 1273152..1273361 (-) | 210 | WP_002220687.1 | hypothetical protein | - |
| B6116_RS06620 (B6116_01244) | - | 1273358..1273498 (-) | 141 | WP_002220688.1 | hypothetical protein | - |
| B6116_RS06625 (B6116_01245) | - | 1273498..1273689 (-) | 192 | WP_002219435.1 | type ISP restriction/modification enzyme | - |
| B6116_RS06630 (B6116_01246) | - | 1273692..1273985 (-) | 294 | WP_002220689.1 | hypothetical protein | - |
| B6116_RS06635 (B6116_01247) | - | 1273982..1274242 (-) | 261 | WP_002220690.1 | NGO1622 family putative holin | - |
| B6116_RS06640 (B6116_01248) | - | 1274278..1274493 (-) | 216 | WP_002220692.1 | hypothetical protein | - |
| B6116_RS06645 (B6116_01249) | - | 1274565..1275419 (-) | 855 | WP_002220693.1 | YfdQ family protein | - |
| B6116_RS06650 (B6116_01250) | - | 1275444..1275803 (-) | 360 | WP_002220694.1 | hypothetical protein | - |
| B6116_RS06655 (B6116_01251) | - | 1275871..1276071 (-) | 201 | WP_002219431.1 | hypothetical protein | - |
| B6116_RS06660 (B6116_01252) | - | 1276302..1276727 (-) | 426 | WP_002220695.1 | hypothetical protein | - |
| B6116_RS06665 (B6116_01253) | - | 1276830..1277546 (-) | 717 | WP_002220696.1 | LexA family transcriptional regulator | - |
| B6116_RS06670 (B6116_01254) | - | 1277946..1278293 (+) | 348 | WP_002220698.1 | hypothetical protein | - |
| B6116_RS06675 (B6116_01255) | - | 1278408..1281254 (+) | 2847 | WP_002220699.1 | primase-helicase family protein | - |
| B6116_RS06680 (B6116_01256) | - | 1281271..1281480 (+) | 210 | WP_002220700.1 | hypothetical protein | - |
| B6116_RS06685 (B6116_01257) | - | 1281483..1281869 (+) | 387 | WP_002220701.1 | DUF3310 domain-containing protein | - |
| B6116_RS06690 (B6116_01258) | - | 1281856..1282110 (+) | 255 | WP_002220702.1 | hypothetical protein | - |
| B6116_RS06695 (B6116_01259) | - | 1282119..1283681 (+) | 1563 | WP_002220703.1 | phage portal protein | - |
| B6116_RS06700 (B6116_01260) | - | 1283662..1285554 (+) | 1893 | WP_002220704.1 | phage major capsid protein | - |
| B6116_RS06705 (B6116_01261) | - | 1285612..1285839 (+) | 228 | WP_002220705.1 | hypothetical protein | - |
| B6116_RS06710 (B6116_01262) | - | 1285832..1286134 (+) | 303 | WP_002244523.1 | head-tail joining protein | - |
| B6116_RS06715 (B6116_01263) | - | 1286115..1286534 (+) | 420 | WP_002244524.1 | hypothetical protein | - |
| B6116_RS06720 (B6116_01264) | - | 1286566..1287207 (+) | 642 | WP_002220708.1 | phage tail protein | - |
| B6116_RS06725 (B6116_01265) | - | 1287271..1287582 (+) | 312 | WP_002220709.1 | phage tail assembly chaperone | - |
| B6116_RS06730 | - | 1287630..1287902 (+) | 273 | WP_002220710.1 | DUF1799 domain-containing protein | - |
| B6116_RS06735 (B6116_01266) | - | 1287895..1291113 (+) | 3219 | WP_002224445.1 | phage tail length tape measure family protein | - |
| B6116_RS06740 (B6116_01267) | - | 1291135..1291404 (+) | 270 | WP_002217457.1 | phage tail protein | - |
| B6116_RS06745 (B6116_01268) | - | 1291464..1292186 (+) | 723 | WP_002217456.1 | phage minor tail protein L | - |
| B6116_RS06750 (B6116_01269) | - | 1292183..1292938 (+) | 756 | WP_002244525.1 | C40 family peptidase | - |
| B6116_RS06755 (B6116_01270) | - | 1292935..1293657 (+) | 723 | WP_002220716.1 | tail assembly protein | - |
| B6116_RS06760 (B6116_01271) | gpJ | 1293793..1298058 (+) | 4266 | WP_002244526.1 | TipJ family phage tail tip protein | - |
| B6116_RS06765 (B6116_01272) | - | 1298129..1298575 (+) | 447 | WP_002241437.1 | hypothetical protein | - |
| B6116_RS15290 (B6116_01273) | - | 1298592..1298798 (+) | 207 | WP_002217448.1 | hypothetical protein | - |
| B6116_RS06775 (B6116_01274) | - | 1298866..1299237 (+) | 372 | WP_002217445.1 | hypothetical protein | - |
| B6116_RS06780 (B6116_01275) | - | 1299301..1299726 (+) | 426 | WP_002220721.1 | hypothetical protein | - |
| B6116_RS06785 (B6116_01276) | - | 1299723..1299998 (+) | 276 | WP_002217443.1 | hypothetical protein | - |
| B6116_RS06790 (B6116_01277) | - | 1300137..1300610 (+) | 474 | WP_002220733.1 | D-Ala-D-Ala carboxypeptidase family metallohydrolase | - |
| B6116_RS06795 (B6116_01278) | - | 1300622..1301131 (+) | 510 | WP_002220734.1 | hypothetical protein | - |
| B6116_RS06800 (B6116_01279) | - | 1301184..1301531 (-) | 348 | WP_002217440.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| B6116_RS06805 (B6116_01280) | - | 1301533..1301769 (-) | 237 | WP_002217439.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| B6116_RS06810 (B6116_01281) | - | 1302128..1302766 (-) | 639 | WP_002244527.1 | DUF4760 domain-containing protein | - |
| B6116_RS14745 | - | 1302871..1303041 (-) | 171 | WP_164728559.1 | hypothetical protein | - |
| B6116_RS06815 (B6116_01282) | - | 1303057..1303425 (-) | 369 | WP_002217436.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| B6116_RS15210 (B6116_01283) | - | 1303422..1303553 (-) | 132 | WP_002217434.1 | hypothetical protein | - |
| B6116_RS06825 (B6116_01284) | - | 1303969..1304963 (-) | 995 | Protein_1289 | IS5 family transposase | - |
| B6116_RS06830 (B6116_01285) | - | 1305004..1305843 (+) | 840 | WP_002214477.1 | hypothetical protein | - |
| B6116_RS06835 (B6116_01287) | - | 1306113..1307375 (-) | 1263 | WP_002214479.1 | HlyD family secretion protein | - |
| B6116_RS06840 (B6116_01288) | - | 1307377..1309473 (-) | 2097 | WP_002244529.1 | peptidase domain-containing ABC transporter | - |
| B6116_RS06845 | - | 1309690..1310025 (-) | 336 | WP_002214483.1 | hypothetical protein | - |
| B6116_RS06855 | - | 1310618..1310953 (-) | 336 | WP_014574212.1 | hypothetical protein | - |
| B6116_RS06860 (B6116_01291) | - | 1311195..1312343 (-) | 1149 | WP_025462963.1 | JmjC domain-containing protein | - |
| B6116_RS06865 (B6116_01292) | - | 1312519..1312722 (-) | 204 | WP_002214489.1 | hypothetical protein | - |
| B6116_RS14890 | - | 1312765..1313058 (-) | 294 | WP_002214491.1 | hypothetical protein | - |
| B6116_RS15295 | - | 1313071..1313172 (-) | 102 | Protein_1298 | peptide transporter | - |
| B6116_RS14895 (B6116_01293) | - | 1313185..1313409 (-) | 225 | WP_002234261.1 | AAA family ATPase | - |
| B6116_RS06880 (B6116_01294) | - | 1313756..1314763 (-) | 1008 | WP_047957336.1 | IS5 family transposase | - |
| B6116_RS13865 | - | 1314827..1314961 (-) | 135 | Protein_1301 | IS110 family transposase | - |
| B6116_RS06885 (B6116_01295) | - | 1316129..1318354 (-) | 2226 | WP_002244532.1 | NADP-dependent isocitrate dehydrogenase | - |
Sequence
Protein
Download Length: 221 a.a. Molecular weight: 24556.04 Da Isoelectric Point: 9.4348
>NTDB_id=122201 B6116_RS06525 WP_047957332.1 1258368..1259033(+) (pilH) [Neisseria meningitidis strain B6116/77]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKGGAPN
NKCDFGKKGQGMLAFGDKNGNKTYDGDTADVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYST
NQDLTNTSRFVYSDGYIQIVLTDARAVSDADKKFRSAVVLIDSSGRVEVCPRNDRRAVCQH
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAEQVANLLRFSRGEAVRLNLPVYICPVQVKKGGAPN
NKCDFGKKGQGMLAFGDKNGNKTYDGDTADVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYST
NQDLTNTSRFVYSDGYIQIVLTDARAVSDADKKFRSAVVLIDSSGRVEVCPRNDRRAVCQH
Nucleotide
Download Length: 666 bp
>NTDB_id=122201 B6116_RS06525 WP_047957332.1 1258368..1259033(+) (pilH) [Neisseria meningitidis strain B6116/77]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGAGAAGCCGTCCGGCTCAATCTTCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGGCGGTGCGCCCAAC
AATAAATGTGACTTCGGCAAGAAGGGGCAGGGAATGTTGGCTTTTGGCGATAAGAATGGCAATAAGACATATGACGGCGA
TACGGCGGATGTTCTCCTTCGCAGTGTGGTATTGAATGATGATATCAATGATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTTGGTCAGACTCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATTCTACC
AATCAGGATCTCACGAATACTTCCAGATTTGTTTACTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGCCCTAGAAACG
ATAGGCGTGCCGTATGCCAACATTAA
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCAGGTTGCCAACCTTTTGCGTT
TCTCCAGGGGAGAAGCCGTCCGGCTCAATCTTCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGGCGGTGCGCCCAAC
AATAAATGTGACTTCGGCAAGAAGGGGCAGGGAATGTTGGCTTTTGGCGATAAGAATGGCAATAAGACATATGACGGCGA
TACGGCGGATGTTCTCCTTCGCAGTGTGGTATTGAATGATGATATCAATGATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTTGGTCAGACTCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATTCTACC
AATCAGGATCTCACGAATACTTCCAGATTTGTTTACTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGCCCTAGAAACG
ATAGGCGTGCCGTATGCCAACATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilH | Neisseria gonorrhoeae MS11 |
86.425 |
100 |
0.864 |