Detailed information NTG0122116

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ER16_RS14005
• Genome accession: NZ_CP007659
• Coordinates: 2745898..2746785 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain H-EMRSA-15
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2740898..2751785

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ER16_RS13970	-	2740916..2741004 (+)	89	Protein_2663	hypothetical protein	-
ER16_RS13975 (ER16_13330)	-	2741112..2741609 (-)	498	WP_001065267.1	glutathione peroxidase	-
ER16_RS13980	-	2741619..2741879 (-)	261	WP_072434822.1	hypothetical protein	-
ER16_RS13985	-	2742261..2742374 (-)	114	WP_072384844.1	hypothetical protein	-
ER16_RS13995 (ER16_13335)	-	2743038..2745038 (-)	2001	WP_000776746.1	ABC transporter permease	-
ER16_RS14000 (ER16_13340)	-	2745035..2745790 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
ER16_RS14005 (ER16_13345)	braS	2745898..2746785 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ER16_RS14010 (ER16_13350)	braR	2746796..2747461 (-)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ER16_RS14015 (ER16_13355)	-	2747487..2747687 (-)	201	WP_000604723.1	hypothetical protein	-
ER16_RS14025 (ER16_13360)	-	2747885..2749309 (+)	1425	WP_000953731.1	alkaline phosphatase	-
ER16_RS15655	-	2749369..2749470 (-)	102	WP_000731972.1	SE2200 family small protein	-
ER16_RS14030 (ER16_13370)	-	2749592..2750047 (-)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
ER16_RS14035 (ER16_13375)	-	2750293..2751054 (-)	762	WP_000323451.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=122116 ER16_RS14005 WP_000143420.1 2745898..2746785(-) (braS) [Staphylococcus aureus strain H-EMRSA-15]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=122116 ER16_RS14005 WP_000143420.1 2745898..2746785(-) (braS) [Staphylococcus aureus strain H-EMRSA-15]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993