Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ER16_RS10760 Genome accession   NZ_CP007659
Coordinates   2123168..2123884 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain H-EMRSA-15     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2118168..2128884
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ER16_RS10730 (ER16_10285) - 2118476..2119102 (+) 627 WP_000522384.1 nitroreductase family protein -
  ER16_RS10735 (ER16_10290) - 2119372..2120157 (+) 786 WP_000867943.1 carbon-nitrogen family hydrolase -
  ER16_RS15645 hld 2120756..2120836 (-) 81 WP_000046022.1 delta-hemolysin -
  ER16_RS10745 (ER16_10300) agrB 2121126..2121695 (+) 570 WP_001105713.1 accessory gene regulator AgrB -
  ER16_RS10750 (ER16_10305) agrD 2121692..2121832 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  ER16_RS10755 agrC 2121857..2123149 (+) 1293 WP_001670396.1 quorum-sensing sensor histidine kinase AgrC -
  ER16_RS10760 (ER16_10315) agrA 2123168..2123884 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ER16_RS10765 - 2123956..2124063 (+) 108 WP_031789494.1 hypothetical protein -
  ER16_RS10770 (ER16_10320) - 2124252..2125211 (-) 960 WP_001253301.1 carbohydrate kinase family protein -
  ER16_RS10775 (ER16_10325) - 2125208..2126692 (-) 1485 WP_000141410.1 sucrose-6-phosphate hydrolase -
  ER16_RS10780 (ER16_10330) - 2126841..2127791 (-) 951 WP_000790322.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=122112 ER16_RS10760 WP_000688492.1 2123168..2123884(+) (agrA) [Staphylococcus aureus strain H-EMRSA-15]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=122112 ER16_RS10760 WP_000688492.1 2123168..2123884(+) (agrA) [Staphylococcus aureus strain H-EMRSA-15]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATCCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCATAGTGAACTTACGTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACACGTATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATCGAATCTATAG
ATTCGAAAGAGCGCATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment