Detailed information NTG0122073

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EP20_RS14000
• Genome accession: NZ_CP007657
• Coordinates: 2727274..2728161 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain V2200
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2722274..2733161

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EP20_RS13965	-	2722293..2722385 (+)	93	WP_010956583.1	hypothetical protein	-
EP20_RS13970 (EP20_013150)	-	2722493..2722990 (-)	498	WP_001065268.1	glutathione peroxidase	-
EP20_RS13975	-	2723000..2723260 (-)	261	WP_001789910.1	hypothetical protein	-
EP20_RS13980	-	2723642..2723755 (-)	114	WP_001791776.1	hypothetical protein	-
EP20_RS13990 (EP20_013155)	-	2724414..2726414 (-)	2001	WP_000776751.1	ABC transporter permease	-
EP20_RS13995 (EP20_013160)	-	2726411..2727166 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
EP20_RS14000 (EP20_013165)	braS	2727274..2728161 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EP20_RS14005 (EP20_013170)	braR	2728172..2728837 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EP20_RS14010 (EP20_013175)	-	2728863..2729063 (-)	201	WP_000604728.1	hypothetical protein	-
EP20_RS14020 (EP20_013180)	-	2729261..2730685 (+)	1425	WP_000953744.1	alkaline phosphatase	-
EP20_RS15615	-	2730755..2730865 (+)	111	WP_001791296.1	hypothetical protein	-
EP20_RS14025 (EP20_013190)	-	2730968..2731423 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
EP20_RS14030 (EP20_013195)	-	2731668..2732429 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=122073 EP20_RS14000 WP_000143419.1 2727274..2728161(-) (braS) [Staphylococcus aureus strain V2200]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=122073 EP20_RS14000 WP_000143419.1 2727274..2728161(-) (braS) [Staphylococcus aureus strain V2200]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997