Detailed information NTG0121977

Bioinformatically predicted

Overview

• Name: luxQ
• Type: Regulator
• Locus tag: EN18_RS16145
• Genome accession: NZ_CP007635
• Coordinates: 382253..384826 (-)
• Length: 857 a.a.
• NCBI ID: WP_001026306.1
• Uniprot ID: Q9KLK7
• Organism: Vibrio cholerae strain 2012EL-2176
• Function: autoinducer sensor (predicted from homology) Competence regulation

Genomic Context

Location: 377253..389826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EN18_RS16120 (EN18_02005)	-	379676..379981 (-)	306	WP_001181134.1	hypothetical protein	-
EN18_RS16125 (EN18_02010)	-	380184..380582 (+)	399	WP_000831416.1	YgiW/YdeI family stress tolerance OB fold protein	-
EN18_RS16135 (EN18_02020)	-	380834..381352 (+)	519	WP_000914961.1	hypothetical protein	-
EN18_RS16140 (EN18_02025)	-	381596..382261 (+)	666	WP_000268204.1	flagellar brake protein	-
EN18_RS16145 (EN18_02030)	luxQ	382253..384826 (-)	2574	WP_001026306.1	quorum-sensing autoinducer 2 sensor kinase/phosphatase LuxQ	Regulator
EN18_RS16150 (EN18_02035)	luxP	384844..385938 (-)	1095	WP_000823678.1	autoinducer 2-binding periplasmic protein LuxP	Regulator
EN18_RS16155 (EN18_02040)	traF	386150..387310 (-)	1161	WP_001025860.1	conjugal transfer protein TraF	-
EN18_RS22000	-	387412..387717 (-)	306	Protein_407	GIY-YIG nuclease family protein	-
EN18_RS16160 (EN18_02050)	-	387734..388384 (-)	651	WP_001025631.1	YceH family protein	-
EN18_RS16165 (EN18_02055)	-	388426..388623 (-)	198	WP_001246071.1	hypothetical protein	-
EN18_RS16170 (EN18_02060)	-	388811..389131 (+)	321	WP_001089529.1	DUF496 family protein	-
EN18_RS16180 (EN18_02070)	-	389544..389795 (+)	252	WP_001882582.1	YgjV family protein	-

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 96929.73 Da
• Isoelectric Point: 6.0197

>NTDB_id=121977 EN18_RS16145 WP_001026306.1 382253..384826(-) (luxQ) [Vibrio cholerae strain 2012EL-2176]
MNIRPSQIKHKQRIASFITHAVVVVMGVLIVSVLFQSYQISSRLMAQEGQRTSVQTSSLIQSLFDFRLAALRIHQDSTAK
NASLINALVSRDSSRLDEFFSSVDELELSNAPDLRFISSHDNILWDDGNASFYGIAQQELNKLIRRVAISGNWHLVQTPS
EGKSVHILMRRSSLIEAGTGQVVGYLYVGIVLNDNFALLENIRSGSNSENLVLAVDTTPLVSTLKGNEPYSLDYVVHSAK
DAMRDSFIVGQTFLEVESVPTYLCVYSIQTNQNVLTLRDNFYFWMAFALISMIGVSIASRWWLQKRIQREIETLMNYTHK
LMDLDTKSEFIGSKIYEFDYFGRTLEQSFRRLANKEKQFEDLFNFALSPTMLWNTSGRLIRMNPSAQIQFLREDAQNHFL
FEILERQLLPTITNAAQGNNPSDVTTEVDGRVYRWNLSPIMVEGQIISIITQGQDITTIAEAEKQSQAARREAEESARVR
AEFLAKMSHELRTPLNGVLGVSQLLKRTPLNDEQREHVAVLCSSGEHLLAVLNDILDFSRLEQGKFRIQKNEFRLKELVC
AIDRIYRPLCNEKGLELVVNSNITTAAIVRSDQIRINQILFNLLNNAIKFTHQGSIRVELQLIEGDPLAQLVIQVVDTGI
GIREQDLTVIFEPFMQAESTTTREYGGSGLGLTIVHSLVEMLSGQLHVSSEYGIGTRFEIQLPIELVEKPDAPQQLLPAP
DPQPLFDKTLRVLLVEDNHTNAFIAQAFCRKYGLDVSWVTDGLQAIEELKIHDYDLVLMDNQLPYLDGVETTRTIKKVLH
LPVVVYACTADGLEETRQAFFHAGAEYVLVKPLKEQTLHKALEHFKHHHGQKNAGLN

Nucleotide

• Length: 2574 bp

>NTDB_id=121977 EN18_RS16145 WP_001026306.1 382253..384826(-) (luxQ) [Vibrio cholerae strain 2012EL-2176]
TTGAACATTCGACCTAGCCAAATCAAGCATAAACAGCGCATCGCTTCTTTTATCACCCATGCTGTCGTGGTGGTGATGGG
CGTTCTGATCGTCAGTGTATTATTCCAAAGTTACCAGATCAGTAGCCGCTTGATGGCTCAAGAAGGACAACGCACTTCAG
TTCAAACCTCCAGCTTGATTCAAAGTTTGTTTGATTTTCGTCTTGCGGCACTGCGAATTCACCAGGACAGCACAGCCAAG
AACGCCAGTTTAATCAACGCACTTGTCAGCCGAGATTCGAGTCGGCTGGATGAATTCTTTTCCAGTGTTGATGAACTTGA
ACTCTCTAATGCGCCAGATCTGCGTTTTATCTCCAGTCACGACAACATCTTGTGGGATGATGGCAACGCCTCTTTTTACG
GCATTGCCCAGCAAGAGCTGAATAAGCTTATCCGCAGAGTGGCGATTAGTGGCAATTGGCACTTGGTTCAAACGCCCAGC
GAGGGAAAATCAGTCCATATTTTGATGCGTCGTTCATCGCTGATTGAAGCGGGAACCGGGCAGGTTGTTGGGTATCTGTA
TGTAGGCATCGTACTCAATGATAACTTTGCGCTGTTGGAAAATATCCGCAGTGGCAGTAACTCAGAAAACCTAGTCCTTG
CCGTGGATACTACGCCGCTGGTTTCTACCTTGAAAGGCAATGAACCTTATTCGCTGGACTATGTGGTGCACAGCGCCAAA
GATGCTATGCGAGACAGCTTTATTGTTGGGCAAACCTTCTTAGAAGTGGAAAGTGTACCGACCTATCTGTGCGTCTACTC
GATTCAGACCAACCAAAATGTGCTCACCCTGCGGGATAATTTCTATTTTTGGATGGCGTTTGCGCTGATCAGTATGATCG
GTGTTTCCATAGCGTCACGCTGGTGGCTACAAAAACGCATTCAGCGTGAAATTGAAACCTTGATGAATTACACCCATAAA
TTGATGGATCTGGATACGAAAAGTGAGTTTATCGGTTCAAAAATTTATGAGTTCGACTATTTTGGGCGAACGTTGGAACA
ATCATTCCGTCGTCTCGCCAATAAAGAAAAGCAGTTTGAAGATCTGTTTAACTTTGCGCTTTCACCGACCATGCTTTGGA
ATACCTCTGGTCGGCTGATCCGCATGAACCCCTCAGCGCAAATCCAGTTTTTGCGCGAAGATGCGCAAAACCATTTCTTA
TTTGAGATTCTTGAACGCCAACTGTTGCCGACCATCACTAATGCGGCACAGGGCAATAATCCGAGTGACGTCACAACCGA
AGTGGATGGTCGTGTGTACCGCTGGAACCTTTCACCGATCATGGTGGAAGGGCAGATCATTTCCATCATTACTCAAGGGC
AAGATATCACCACCATCGCGGAAGCGGAGAAGCAAAGCCAAGCCGCAAGGCGCGAAGCGGAAGAGTCGGCACGGGTCAGG
GCCGAGTTTTTGGCCAAAATGAGTCACGAATTGCGCACGCCGCTCAATGGTGTGCTCGGTGTTTCCCAACTGCTAAAACG
GACCCCACTCAATGATGAACAGCGCGAACACGTGGCTGTGTTATGCAGCAGTGGTGAACATTTGCTCGCGGTGCTGAATG
ACATCTTGGATTTCTCACGCTTAGAGCAGGGCAAATTCCGTATTCAAAAGAATGAGTTTCGCCTTAAAGAGTTGGTGTGC
GCGATTGACCGCATTTATCGACCTTTATGTAATGAAAAAGGCTTGGAACTGGTGGTGAATTCCAATATCACTACCGCAGC
GATTGTGCGCAGCGATCAGATCCGGATTAACCAAATCTTGTTCAATTTGCTCAATAACGCGATCAAGTTTACTCACCAAG
GTTCGATACGTGTCGAATTGCAATTAATTGAAGGTGATCCATTAGCTCAGCTGGTGATTCAAGTCGTCGATACGGGGATT
GGTATCCGCGAACAAGATTTAACGGTGATTTTTGAACCCTTCATGCAAGCTGAATCGACCACCACTCGAGAGTACGGCGG
AAGTGGTTTAGGCTTAACGATTGTGCACAGTTTAGTGGAAATGCTCAGTGGTCAACTGCACGTCAGCTCCGAGTATGGCA
TTGGTACACGTTTTGAAATTCAGTTACCGATTGAGCTGGTAGAAAAACCGGATGCGCCGCAGCAGTTGTTACCAGCTCCT
GATCCTCAACCGTTATTTGATAAAACTCTGCGTGTACTGTTGGTGGAGGATAACCACACCAATGCCTTTATTGCTCAAGC
ATTCTGTCGTAAATATGGCTTAGATGTGAGCTGGGTAACGGATGGACTACAGGCGATTGAAGAGCTCAAAATACATGACT
ACGACTTAGTGCTGATGGATAACCAGTTACCCTATTTGGATGGCGTTGAGACCACGCGCACCATCAAAAAAGTGCTGCAC
CTTCCGGTGGTGGTGTATGCCTGCACTGCGGATGGCTTAGAAGAAACACGGCAAGCATTTTTCCATGCGGGCGCGGAATA
TGTGTTAGTGAAGCCACTGAAAGAGCAGACTTTGCATAAAGCGCTGGAGCATTTCAAACATCATCATGGCCAAAAAAACG
CTGGCTTAAATTGA

Domains

Predicted by InterproScan.

• LuxQ, periplasmic (LuxQ-periplasm) (41-277)

• Response regulator receiver domain (Response_reg) (732-842)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (592-705)

• His Kinase A (phospho-acceptor) domain (HisKA) (480-544)

3D structure

• PDB: 3C30
• PDB: 3C38

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
luxQ	Vibrio cholerae strain A1552	100	100	1