Detailed information    

insolico Bioinformatically predicted

Overview

Name   hapR   Type   Regulator
Locus tag   EN18_RS14075 Genome accession   NZ_CP007634
Coordinates   3035368..3035979 (-) Length   203 a.a.
NCBI ID   WP_000340098.1    Uniprot ID   B2CKP3
Organism   Vibrio cholerae strain 2012EL-2176     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3030368..3040979
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN18_RS14050 (EN18_19880) - 3030892..3031461 (-) 570 WP_000836326.1 BON domain-containing protein -
  EN18_RS14055 (EN18_19885) - 3031464..3032054 (-) 591 WP_000887295.1 phosphoheptose isomerase -
  EN18_RS14060 (EN18_19890) - 3032058..3032426 (-) 369 WP_001893625.1 YraN family protein -
  EN18_RS14065 (EN18_19895) - 3032413..3034218 (-) 1806 WP_001015481.1 penicillin-binding protein activator -
  EN18_RS14070 (EN18_19900) rsmI 3034288..3035154 (+) 867 WP_000131542.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  EN18_RS14075 (EN18_19905) hapR 3035368..3035979 (-) 612 WP_000340098.1 quorum-sensing master transcriptional regulator HapR Regulator
  EN18_RS14080 (EN18_19910) hpt 3036275..3036808 (+) 534 WP_000683351.1 hypoxanthine phosphoribosyltransferase -
  EN18_RS14085 (EN18_19915) can 3036883..3037551 (-) 669 WP_001114117.1 carbonate dehydratase -
  EN18_RS14090 (EN18_19920) - 3037699..3039345 (+) 1647 WP_000484911.1 SulP family inorganic anion transporter -
  EN18_RS14095 (EN18_19925) - 3039729..3040646 (+) 918 WP_000271063.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 203 a.a.        Molecular weight: 23692.39 Da        Isoelectric Point: 6.6356

>NTDB_id=121972 EN18_RS14075 WP_000340098.1 3035368..3035979(-) (hapR) [Vibrio cholerae strain 2012EL-2176]
MDASIEKRPRTRLSPQKRKLQLMEIALEVFAKRGIGRGGHADIAEIAQVSVATVFNYFPTREDLVDDVLNFVVRQYSNFL
TDHIDLDLDVKTNLQTLCKEMVKLAMTDCHWLKVWFEWSASTRDEVWPLFVSTNRTNQLLIRNMFMKAMERGELCEKHDV
DNMASLFHGIFYSIFLQVNRLGEQEAVYKLADSYLNMLCIYKN

Nucleotide


Download         Length: 612 bp        

>NTDB_id=121972 EN18_RS14075 WP_000340098.1 3035368..3035979(-) (hapR) [Vibrio cholerae strain 2012EL-2176]
ATGGACGCATCAATCGAAAAACGCCCTCGAACTCGGCTATCGCCTCAAAAACGCAAACTACAACTGATGGAAATCGCGTT
GGAAGTGTTTGCTAAACGCGGCATTGGTCGTGGTGGTCACGCAGATATTGCCGAGATTGCGCAAGTCTCCGTTGCAACAG
TGTTCAACTACTTCCCAACTCGTGAAGACTTGGTTGACGATGTGCTGAATTTTGTGGTTCGTCAGTACTCCAACTTCTTG
ACCGATCACATCGATCTTGATTTGGATGTGAAAACCAACCTACAAACTCTGTGCAAAGAGATGGTGAAATTGGCGATGAC
CGATTGTCACTGGCTCAAAGTCTGGTTTGAGTGGAGTGCTTCAACCCGTGACGAAGTTTGGCCACTGTTTGTTTCCACCA
ACCGAACTAACCAACTGCTGATCAGAAACATGTTTATGAAAGCGATGGAGCGTGGCGAATTGTGTGAGAAACACGATGTC
GATAACATGGCCAGCCTGTTCCACGGCATCTTCTACTCCATCTTCTTACAAGTGAACCGTTTAGGTGAACAAGAAGCAGT
GTATAAGTTGGCCGATAGCTACCTCAATATGCTGTGTATCTATAAGAACTAG

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, tetR family (TetR_N)

(23-67)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 6D7R
  PDB 7XXN
  PDB 7XXO
  PDB 7XXS
  PDB 7XXT
  PDB 7XY0
  PDB 7XY5
  PDB 7XYI
  PDB 7Y4J

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hapR Vibrio cholerae C6706

100

100

1
  hapR Vibrio cholerae strain A1552

100

100

1
  opaR Vibrio parahaemolyticus RIMD 2210633

72.222

97.537

0.704

Multiple sequence alignment