Detailed information NTG0121956

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: EN18_RS10525
• Genome accession: NZ_CP007634
• Coordinates: 2314596..2315603 (-)
• Length: 335 a.a.
• NCBI ID: WP_000224452.1
• Uniprot ID: A0A085RG68
• Organism: Vibrio cholerae strain 2012EL-2176
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 2309596..2320603

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EN18_RS10500 (EN18_16365)	rraA	2310171..2310686 (-)	516	WP_000456236.1	ribonuclease E activity regulator RraA	-
EN18_RS10505 (EN18_16370)	-	2310761..2311678 (-)	918	WP_001066162.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
EN18_RS10510 (EN18_16375)	hslU	2311782..2313113 (-)	1332	WP_001293370.1	HslU--HslV peptidase ATPase subunit	-
EN18_RS10515 (EN18_16380)	hslV	2313179..2313736 (-)	558	WP_000208249.1	ATP-dependent protease subunit HslV	-
EN18_RS10520 (EN18_16385)	-	2313873..2314424 (-)	552	WP_001884022.1	SPOR domain-containing protein	-
EN18_RS10525 (EN18_16390)	cytR	2314596..2315603 (-)	1008	WP_000224452.1	DNA-binding transcriptional regulator CytR	Regulator
EN18_RS10530 (EN18_16395)	priA	2315909..2318113 (-)	2205	WP_001247858.1	primosomal protein N'	-
EN18_RS10535 (EN18_16400)	rpmE	2318368..2318586 (+)	219	WP_000643446.1	50S ribosomal protein L31	-
EN18_RS10540 (EN18_16405)	-	2318894..2320171 (+)	1278	WP_001278588.1	malic enzyme-like NAD(P)-binding protein	-
EN18_RS10545 (EN18_16410)	metJ	2320282..2320599 (-)	318	WP_000796267.1	met regulon transcriptional regulator MetJ	-

Sequence

Protein

• Length: 335 a.a.
• Molecular weight: 37018.59 Da
• Isoelectric Point: 7.0759

>NTDB_id=121956 EN18_RS10525 WP_000224452.1 2314596..2315603(-) (cytR) [Vibrio cholerae strain 2012EL-2176]
MATMKDVAQLAGVSTATVSRALMNPEKVSSSTRKRVEEAVLEAGYSPNSLARNLRRNESKTIVAIVPDICDPYFSEIIRG
IEDAAMEHGYLVLLGDSGQQKRRENSFVNLVFTKQADGMLLLGTDLPFDVSKPEQKNLPPMVMACEFAPELELPTVHIDN
LTSAFEAVNYLTQLGHKRIAQISGPQHAALCQFRHQGYQQALRRAGITMNPTYCTFGDFTFEAGAKAVRQLLALPEQPTA
IFCHNDTMAIGAIQEAKRLGLRVPQDLSVVGFDDIQFAQYCDPPLTTISQPRYEIGRQAMLMMLELLRGHDVRAGSRLLE
TKLVVRESAAPPSKK

Nucleotide

• Length: 1008 bp

>NTDB_id=121956 EN18_RS10525 WP_000224452.1 2314596..2315603(-) (cytR) [Vibrio cholerae strain 2012EL-2176]
ATGGCGACAATGAAGGATGTTGCCCAGCTTGCTGGAGTTTCAACCGCGACCGTGTCTCGTGCGTTGATGAATCCAGAGAA
AGTCTCGTCGTCCACTCGTAAACGAGTGGAAGAGGCCGTGCTGGAAGCGGGTTACTCACCCAATTCTTTGGCGCGCAATT
TGCGCCGTAATGAATCGAAAACCATCGTTGCTATCGTGCCAGATATCTGTGATCCCTACTTTTCTGAGATCATTCGCGGT
ATTGAAGATGCCGCGATGGAGCACGGTTATCTGGTGCTGTTGGGGGATAGTGGTCAACAGAAGCGTCGGGAGAACTCGTT
CGTTAATCTGGTGTTTACCAAACAGGCAGACGGTATGTTGCTGCTGGGGACAGATTTGCCGTTTGATGTGAGTAAACCTG
AGCAGAAAAACCTACCGCCTATGGTGATGGCGTGTGAATTTGCGCCAGAGCTGGAATTGCCAACGGTACACATTGATAAC
CTGACCTCGGCATTTGAGGCGGTAAACTATCTCACTCAGCTTGGGCACAAACGGATTGCGCAGATCTCAGGTCCACAACA
TGCTGCGCTGTGCCAATTCCGTCATCAAGGCTATCAACAGGCGTTGCGTCGTGCTGGCATCACCATGAACCCGACTTACT
GCACTTTTGGCGATTTCACTTTTGAAGCCGGGGCAAAAGCGGTGCGTCAGCTGTTGGCATTGCCTGAGCAGCCGACCGCG
ATTTTCTGTCATAACGATACGATGGCGATTGGCGCAATTCAGGAAGCGAAGCGACTTGGCTTGCGCGTACCGCAAGATCT
CTCTGTGGTCGGTTTTGACGATATTCAGTTTGCCCAGTACTGCGATCCCCCATTAACCACCATTTCGCAGCCGCGTTATG
AGATTGGCCGTCAAGCCATGCTGATGATGCTTGAGCTGCTTCGCGGACACGATGTACGTGCTGGATCGCGTCTTTTGGAG
ACCAAGCTGGTCGTGCGTGAGAGTGCTGCGCCGCCAAGCAAGAAGTAA

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (3-48)

• Periplasmic binding protein-like domain (Peripla_BP_3) (168-328)

3D structure

• AlphaFold DB: A0A085RG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio cholerae C6706	100	100	1
cytR	Vibrio parahaemolyticus RIMD 2210633	90.719	99.701	0.904